Nearly half of medical cannabis patients who used tobacco reported reducing or quitting

Among 650 Canadian medical cannabis patients who used tobacco or nicotine, 49% reported reducing use and 24.6% reported quitting after starting medical cannabis.

Lucas, Philippe et al.·Journal of substance abuse treatment·2021·Moderate EvidenceCross-Sectional
RTHC-03301Cross SectionalModerate Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Of 650 current or former tobacco/nicotine users, 320 (49%) self-reported reductions in use after initiating medical cannabis, with 160 (24.6%) reporting no tobacco/nicotine use in the prior 30 days. Those who specifically intended to use cannabis to quit tobacco had nearly 3 times the odds of reducing use.

Key Numbers

2,102 total participants; 650 current/former T/N users; 49% reported reductions; 24.6% reported cessation; intent to quit via cannabis aOR = 2.79; age 55+ aOR = 2.56; >25 T/N uses/day aOR = 2.11

How They Did This

An online cross-sectional survey of 2,102 Canadian medical cannabis patients examined demographics, cannabis use patterns, and changes in tobacco/nicotine use before and after medical cannabis initiation. Univariate and multivariate logistic regressions assessed associations between key variables and tobacco reduction/cessation.

Why This Research Matters

Tobacco remains the leading preventable cause of death globally. If medical cannabis genuinely helps some people reduce or quit tobacco, it could represent a novel harm reduction strategy, though this study's retrospective design means the association needs further investigation.

The Bigger Picture

The finding that intentional use of cannabis for tobacco cessation predicted greater odds of quitting is intriguing. It also challenges the common assumption that cannabis use necessarily promotes tobacco use.

What This Study Doesn't Tell Us

Cross-sectional retrospective design cannot establish causation. Self-reported data subject to recall bias. No biochemical verification of tobacco cessation. Self-selected medical cannabis patient population. No control group.

Questions This Raises

  • ?Would a randomized trial confirm these associations?
  • ?Which cannabis components or delivery methods are most effective for tobacco reduction?
  • ?Why was involvement with traditional cessation treatments negatively associated with quitting?

Trust & Context

Key Stat:
49% of tobacco-using medical cannabis patients reported reducing tobacco use
Evidence Grade:
Large sample with multivariate analysis, but retrospective cross-sectional design and self-reported outcomes limit causal inference.
Study Age:
Published in 2021.
Original Title:
Self-reported reductions in tobacco and nicotine use following medical cannabis initiation: Results from a cross-sectional survey of authorized medical cannabis patients in Canada.
Published In:
Journal of substance abuse treatment, 130, 108481 (2021)
Database ID:
RTHC-03301

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Did people who intended to use cannabis for quitting tobacco do better?

Yes. Those who specifically intended to use medical cannabis to quit tobacco had 2.79 times the odds of reducing use compared to those without that intention.

Did traditional quit methods help?

Surprisingly, involvement with traditional pharmacological or psychobehavioral cessation treatments was negatively associated with tobacco cessation in this sample (aOR = 0.39), though this likely reflects that people who had already failed other methods turned to cannabis as an alternative.

Read More on RethinkTHC

Cite This Study

RTHC-03301·https://rethinkthc.com/research/RTHC-03301

APA

Lucas, Philippe; Walsh, Zach; Hendricks, Peter S; Boyd, Susan; Milloy, M-J. (2021). Self-reported reductions in tobacco and nicotine use following medical cannabis initiation: Results from a cross-sectional survey of authorized medical cannabis patients in Canada.. Journal of substance abuse treatment, 130, 108481. https://doi.org/10.1016/j.jsat.2021.108481

MLA

Lucas, Philippe, et al. "Self-reported reductions in tobacco and nicotine use following medical cannabis initiation: Results from a cross-sectional survey of authorized medical cannabis patients in Canada.." Journal of substance abuse treatment, 2021. https://doi.org/10.1016/j.jsat.2021.108481

RethinkTHC

RethinkTHC Research Database. "Self-reported reductions in tobacco and nicotine use followi..." RTHC-03301. Retrieved from https://rethinkthc.com/research/lucas-2021-selfreported-reductions-in-tobacco

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.