Cannabis Research Database
6641 Peer-Reviewed Studies
Every study in our database is verified, summarized in plain English, and linked to our articles.
Showing 6641 of 6641 studies
Page 1 of 266
CBD Affects Your Body's Own Cannabis Molecules—But Differently in Men and Women
A rigorous crossover trial found that even 20 mg of CBD altered the body's natural cannabinoid levels—with men and women showing different dose-response patterns.
Abboud, Anita; Chester, Lucy Ann; Hébert, Francois-Olivier; Jutras-Aswad, Didier · Journal of cannabis research
Mayo Clinic Review: Can CBD Help Treat Heart Disease?
Mayo Clinic review of CBD's potential in cardiovascular medicine, covering anti-inflammatory and cardioprotective mechanisms across pericarditis, ischemic heart disease, and heart failure.
Abdalla, Hesham M; Bacon, Adam; VanDolah, Hunter; Dreher, Luke; Pathangey, Girish; Abdelnabi, Mahmoud; Ibrahim, Ramzi; Pereyra, Milagros; Farina, Juan M; Luis, S Allen; Arsanjani, Reza; Ayoub, Chadi · Mayo Clinic proceedings
Should Teens with Tourette Syndrome Try Medical Cannabis? Experts Urge Caution
Expert commentary urging caution about medical cannabis for adolescent Tourette syndrome, highlighting the gap between adult evidence and adolescent safety concerns.
Abi-Jaoude, Elia · BJPsych open
Does Teen Cannabis Exposure Change How Rats Respond to Alcohol Later?
Rat study finds adolescent THC vapor exposure doesn't increase alcohol consumption but alters the psychological framework of drinking behavior differently in males and females.
Acosta-Vargas, Jairo S; de Las Heras-Martínez, Natalia; Marcos, Alberto; Nozal, Leonor; Crego, Antonio L; Ucha, Marcos; Higuera-Matas, Alejandro · Neuropharmacology
Older Adults Using Cannabis for Chronic Pain Had More Depression and Pain Interference Over Time
Among 353 older adults with chronic pain, the small minority using cannabis had more pain interference and depression over time—though the tiny sample size limits conclusions.
Aebischer, Jonathan H; Anderson, Lyndsey M; Dieckmann, Nathan F; Mattek, Nora C; Kaye, Jeffrey A · Clinical gerontologist
Cannabinoid Treatments for Rare and Less-Common Diseases: What We Know So Far
Review of cannabinoid therapies for rare and less-common disorders including unusual epilepsies, movement disorders, and skin diseases, with focus on advanced drug delivery strategies.
Afonso, Silvia; Gonçalves, Joana; Brinca, Ana T; Rosendo, Luana M; Rosado, Tiago; Duarte, Ana Paula; Gallardo, Eugenia · Diseases (Basel
CBD Plus Exercise May Protect Insulin-Producing Cells in Obesity
Rat study shows CBD and aerobic exercise synergistically protect insulin-producing beta cells in obesity through the PI3K/AKT/PDX1 pathway, with CBD driving functional improvement.
Akbarzadeh Zarei, Hamid Reza; Gholami, Mandana; Ghazalian, Farshad; Ghareh, Sahar · Molecular biology reports
How CBD Protects the Heart from Damage After Blood Flow Restoration
Rat study demonstrates CBD protects the heart from ischemia-reperfusion injury by boosting mitochondrial biogenesis and suppressing inflammation through the SIRT-1/PGC-1α pathway.
Aksoy, Fatih; Savran, Mehtap; Uysal, Dincer; Bagci, Ali; Ilhan, Ilter; Imeci, Orhan; Sevuk, Mehmet A; Ozmen, Ozlem; Tepebasi, Muhammet Y; Asci, Halil · Journal of cardiovascular pharmacology
1 in 6 Pregnancies in Michigan Involved Cannabis Use
Statewide Michigan study using both self-report and urine testing finds 1 in 6 pregnancies involved cannabis use, strongly linked to depression, adverse childhood experiences, and socioeconomic factors.
Al-Sahab, Ban; Kerver, Jean M; Alshaarawy, Omayma; Bohnert, Kipling M; Elliott, Michael R; Qiu, Hongxiang; Jaber, Audriyana; Neelam, Harish; Paneth, Nigel · Addiction (Abingdon
Why Pregnant Women Use Cannabis: Mental Health and Emotional Coping Drive Decisions
Qualitative study reveals low-income pregnant cannabis users are primarily motivated by emotional regulation and mental health needs, highlighting systemic barriers to support and informed decision-making.
Alaniz, Kristine; Ngui, Emmanuel M; Laestadius, Linnea; Kako, Peninnah M; Yahaya, Musa; Vance, Tessa · Journal of public health research
Mapping How 100+ Cannabis Plant Compounds Interact with the Body
Review of how cannabis's 100+ compounds interact with molecular targets in the body, highlighting major gaps in understanding beyond THC and CBD, especially for acid cannabinoids.
Alexander, Stephen P H · Current topics in behavioral neurosciences
Cannabis-Based Treatments Reduce MS Spasticity, Meta-Analysis Confirms
Meta-analysis of 9 trials with 2,544 MS patients confirms cannabis-based therapies improve spasticity, especially with longer treatment duration, with mild side effects like dizziness and dry mouth.
AlHabil, Yazan; Saadeddin, Liza; Ishkirat, Hana; Alqam, Mariam; Hossoon, Obada; Hameedi, Seema; Yacoub, Hamzeh; Yasin, Diana; Bahbah, Anita; Oweidat, Majd; Mosa, Hanadi · Clinical therapeutics
Synthetic CBD Alternatives Show Less Toxicity and Protect Brain Cells from Alcohol Damage
Synthetic CBD analogues are over 13 times less toxic than natural CBD to brain cells while maintaining protective effects against alcohol-induced damage, supporting their development for alcohol use disorder.
Almeida, Carolina Aparecida Faria; Salles, Gabriela; Bruno, Vitor; Ribeiro, Jessyca Milene; Silva, Alessandra Oliveira; de Assis Braz, Giulia; Castelhano, Felype Valentim Duarte; Dos Reis Rosa Franco, Graziella; Viegas, Cláudio; Marcourakis, Tania; Torres, Larissa Helena Lobo; Garcia, Raphael Caio Tamborelli · Neurotoxicology
Cannabis Use During Pregnancy Suppresses Key Immune Signals in Mothers
Study finds cannabis use during pregnancy suppresses both pro- and anti-inflammatory immune signals in mothers, providing a potential biological mechanism for adverse birth outcomes.
Alshaarawy, Omayma; Sotzen, Morgan; Kurjan, Emily; Padmanabhan, Vasantha; Ruden, Douglas M; Olson, L Karl · Cannabis and cannabinoid research
Cannabis and Opioid Receptors May Work Through Separate Brain Circuits, Not Direct Interaction
Knockout mouse study challenges the theory that cannabis and opioid receptors interact directly, finding limited brain co-expression and no functional cross-dependence for pain relief or other effects.
Alton, Hannah; Linz, Emily; Bi, Guo-Hua; Soler-Cedeno, Omar; Maras, Maia; Xi, Zheng-Xiong · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Prenatal Cannabis Exposure Linked to Altered Brain Reward Processing and Psychotic Experiences in Youth
Large ABCD Study finds prenatal cannabis exposure alters brain reward processing in children, with blunted striatal responses predicting psychotic-like experiences over 4 years of follow-up.
Amir, Carolyn M; Ghahremani, Dara G; Chang, Sarah E; Cooper, Ziva D; Bearden, Carrie E · Biological psychiatry
Teen Cannabis Use Has Dropped Since 1999 — But Girls Now Use More Than Boys
Three decades of national survey data show US teen cannabis use peaked in 1999 and declined since, but a historic shift has occurred — girls now use more than boys.
Amrock, Stephen M; Sajkiewicz, Agata J · Addictive behaviors
What Would Happen If Sweden Decriminalized Cannabis? A Predictive Model
Predictive model using data from 12 countries estimates that cannabis decriminalization in Sweden would spike experimental use temporarily but could drive sustained increases in regular use.
Andersson, Filip; Ramstedt, Mats; Thiesmeier, Robert; Magnusson, Cecilia; Orsini, Nicola; Galanti, Maria Rosaria · Journal of cannabis research
When Cannabis Causes Both Psychosis and Uncontrollable Vomiting: A Psychiatric Case
Case report of cannabis hyperemesis syndrome developing during psychiatric admission for drug-induced psychosis, highlighting diagnostic challenges and the need for multidisciplinary cannabis-related care.
Anibueze, Bibian K; Emmanuel, Adebayo · Cureus
Adding Cannabis to Alcohol During Pregnancy Increases Risk of Small Babies
California birth data from 2007-2021 shows combining cannabis with alcohol during pregnancy adds 21% higher risk of small babies, while adding tobacco raises preterm birth risk by 44-68%.
Anunziata, Florencia; Frankeberger, Jessica; Baer, Rebecca J; Chambers, Christina; Bandoli, Gretchen · Preventive medicine
First Real-World Driving Study to Test Whether Medical Cannabis Impairs Patients
Protocol for the first real-world on-track driving study testing whether medical cannabis patients are impaired at therapeutic doses, compared to alcohol at the legal driving limit.
Arkell, Thomas R; Hayley, Amie C; Aitken, Blair; Hu, Xinyun; Manning, Brooke; Downey, Luke A · Trials
Canada's Impaired Driving Rose After Legalization — But Enhanced Enforcement May Be Why
Canadian impaired driving reports rose after 2018 cannabis legalization, but analysis suggests enhanced police enforcement and pandemic effects drove the increase more than cannabis sales themselves.
Armstrong, Michael J · American journal of preventive medicine
Depression Predicts Cannabis Initiation in Mexican American Young Adults
Among 616 Mexican American college students who'd never used cannabis, depressive symptoms predicted starting cannabis a year later—family factors didn't buffer it.
Arora, Srishty; North, Caroline; Marti, C Nathan; Schwartz, Seth J; Bataineh, Bara S; Talavera-Garza, Liza; Loukas, Alexandra; Wilkinson, Anna V · Substance use & misuse
Cannabis-Related Psychosis Has a More Chronic Course Than Expected for 'Substance-Induced' Diagnoses
Five-year study of 1,379 first-psychosis patients finds cannabis-related psychosis follows a more chronic course than expected for substance-induced conditions, challenging treatment assumptions.
Aschenbrenner, Erich J; Voluse, Andrew C · Schizophrenia research
Hypothetical Cannabis Purchase Tasks Accurately Predict Real Smoking Behavior
Lab study validates the Marijuana Purchase Task by showing hypothetical cannabis demand closely predicts actual purchasing and smoking behavior, with self-report explaining 66% of consumption variance.
Aston, Elizabeth R; Berey, Benjamin L; Amlung, Michael; Swift, Robert; MacKillop, James; Metrik, Jane · Addiction (Abingdon
This database is maintained by the RethinkTHC research team. All studies listed here have been verified against their original publications. If you notice an error or would like to suggest a study for inclusion, please contact us.
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.