Young adults who said they used cannabis medically were less likely to use illicit drugs

Among young adult cannabis users in Los Angeles, self-reported medical use was associated with lower odds of illicit drug use, while use of cannabis concentrates and edibles predicted higher odds of other drug use.

Fedorova, Ekaterina V et al.·Drug and alcohol dependence·2019·Moderate EvidenceCross-Sectional
RTHC-02029Cross SectionalModerate Evidence2019RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Self-reported medical cannabis use was associated with 50% lower odds of illicit drug use (AOR 0.5). Use of cannabis concentrates increased odds of illicit drug use 2.8x, and edible use doubled the odds of prescription drug misuse. Using cannabis alone (vs. socially) halved prescription misuse odds.

Key Numbers

210 medical cannabis patients, 156 non-patient users, aged 18-26. Medical use: AOR 0.5 for illicit drugs. Concentrate use: AOR 2.8 for illicit drugs. Edible use: AOR 2.0 for prescription misuse. Solitary use: AOR 0.5 for prescription misuse. White race: AOR 3.0 for illicit drugs.

How They Did This

Baseline survey of 210 medical cannabis patients and 156 non-patient cannabis users aged 18-26 in Los Angeles (2014-15), using logistic regression to examine associations between cannabis practices and other drug use.

Why This Research Matters

This distinguishes between different cannabis use patterns rather than treating all use as equivalent. The finding that cannabis form (concentrates, edibles) matters more than frequency challenges the gateway drug framing that focuses on amount of use.

The Bigger Picture

The pattern suggests that how and why people use cannabis matters more than whether they use it. Medical users and solitary users appeared lower-risk, while concentrate and edible users showed higher-risk profiles, possibly reflecting different underlying motivations.

What This Study Doesn't Tell Us

Cross-sectional design cannot determine directionality. Small sample from one city. Self-reported medical use may reflect rationalization rather than genuine medical motivation. Baseline data only from a longitudinal study.

Questions This Raises

  • ?Does medical cannabis access actually reduce illicit drug use, or do lower-risk people self-select into medical use?
  • ?Why are concentrate users at higher risk for other drug use?
  • ?Would these patterns hold in older populations?

Trust & Context

Key Stat:
Medical cannabis users had 50% lower odds of illicit drug use; concentrate users had 2.8x higher odds
Evidence Grade:
Moderate: reasonably sized cross-sectional study with appropriate statistical controls, but cannot establish causation.
Study Age:
Published in 2019, using 2014-15 data.
Original Title:
Illicit drug use and prescription drug misuse among young adult medical cannabis patients and non-patient users in Los Angeles.
Published In:
Drug and alcohol dependence, 198, 21-27 (2019)
Database ID:
RTHC-02029

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does medical cannabis lead to other drug use?

This study found the opposite: self-reported medical cannabis use was associated with 50% lower odds of illicit drug use. However, the form of cannabis mattered, with concentrate use linked to higher other drug use.

Why might the form of cannabis matter?

The study found that concentrate and edible use, but not frequency of overall cannabis use, predicted other drug use. This may reflect different risk profiles or motivations among people who seek out newer, more potent cannabis forms.

Read More on RethinkTHC

Cite This Study

RTHC-02029·https://rethinkthc.com/research/RTHC-02029

APA

Fedorova, Ekaterina V; Schrager, Sheree M; Robinson, Lucy F; Cepeda, Alice; Wong, Carolyn F; Iverson, Ellen; Lankenau, Stephen E. (2019). Illicit drug use and prescription drug misuse among young adult medical cannabis patients and non-patient users in Los Angeles.. Drug and alcohol dependence, 198, 21-27. https://doi.org/10.1016/j.drugalcdep.2019.01.026

MLA

Fedorova, Ekaterina V, et al. "Illicit drug use and prescription drug misuse among young adult medical cannabis patients and non-patient users in Los Angeles.." Drug and alcohol dependence, 2019. https://doi.org/10.1016/j.drugalcdep.2019.01.026

RethinkTHC

RethinkTHC Research Database. "Illicit drug use and prescription drug misuse among young ad..." RTHC-02029. Retrieved from https://rethinkthc.com/research/fedorova-2019-illicit-drug-use-and

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.