A Cannabis Check-Up Program for Young Adults With Psychosis Showed High Acceptance and Completion

A two-session motivational intervention adapted for young adults with psychosis (CCU-P) achieved 92% completion and high satisfaction, using a nonjudgmental approach to provide science-based information about cannabis-psychosis interactions.

Walker, Denise D et al.·Psychiatric rehabilitation journal·2025·Preliminary Evidenceclinical-trial
RTHC-07902Clinical TrialPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
clinical-trial
Evidence
Preliminary Evidence
Sample
N=12

What This Study Found

The Cannabis Check-Up for Psychosis (CCU-P) — a two-session motivational enhancement therapy intervention — demonstrated 92% completion rate (11 of 12 completed both sessions), high satisfaction ratings, and all participants said they would recommend it to others in Coordinated Specialty Care.

Key Numbers

12 participants in the pilot. 92% completed both sessions (11 of 12). All participants would recommend to others. Optimizations included psychosis-specific infographics on rehospitalization risk and harm reduction strategies.

How They Did This

One-arm pilot study with 12 young adults experiencing psychosis who were regular cannabis users enrolled in Coordinated Specialty Care. The intervention was optimized from the Teen Marijuana Check-Up using qualitative interview and focus group data, reviewed by a Stakeholder Advisory Board.

Why This Research Matters

Cannabis use is common among young adults with psychosis and associated with worse outcomes, but few effective interventions exist for this population. Most approaches are too confrontational. This nonjudgmental intervention respects autonomy while providing information to support informed choices.

The Bigger Picture

The cannabis-psychosis relationship is well-established, but telling young adults to 'just stop' doesn't work. Motivational approaches that present information neutrally and support self-directed decision-making may be more effective and better aligned with psychiatric rehabilitation principles.

What This Study Doesn't Tell Us

Very small pilot (n=12), no control group or cannabis use outcome data. Measured feasibility and acceptability, not efficacy. One-arm design cannot determine if the intervention actually changes behavior. Specific to Coordinated Specialty Care settings.

Questions This Raises

  • ?Will CCU-P actually reduce cannabis use or related harms in a larger trial?
  • ?Would the intervention work outside Coordinated Specialty Care?
  • ?Could the nonjudgmental approach be adapted for other substances in psychosis populations?

Trust & Context

Key Stat:
Evidence Grade:
Small feasibility pilot with no control group or efficacy outcomes, but strong acceptability data supporting progression to a larger trial.
Study Age:
Published 2025.
Original Title:
Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.
Published In:
Psychiatric rehabilitation journal, 48(4), 244-253 (2025)
Database ID:
RTHC-07902

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

How does this differ from telling someone with psychosis to stop using cannabis?

Instead of demanding abstinence, CCU-P provides science-based information about cannabis-psychosis interactions through infographics and motivational interviewing, then supports the participant in making their own informed decisions — which research shows is more effective.

Does cannabis make psychosis worse?

Research shows cannabis use is associated with increased rehospitalization risk and recovery challenges in young adults with psychosis. This intervention presents that evidence nonjudgmentally so participants can weigh it against their reasons for use.

Read More on RethinkTHC

Cite This Study

RTHC-07902·https://rethinkthc.com/research/RTHC-07902

APA

Walker, Denise D; Petros, Ryan; Bennett, Melanie; Tennison, Mackenzie; Monroe-DeVita, Maria. (2025). Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.. Psychiatric rehabilitation journal, 48(4), 244-253. https://doi.org/10.1037/prj0000654

MLA

Walker, Denise D, et al. "Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.." Psychiatric rehabilitation journal, 2025. https://doi.org/10.1037/prj0000654

RethinkTHC

RethinkTHC Research Database. "Development of a motivational enhancement therapy cannabis-r..." RTHC-07902. Retrieved from https://rethinkthc.com/research/walker-2025-development-of-a-motivational

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.