A Cannabis Check-Up Program for Young Adults With Psychosis Showed High Acceptance and Completion
A two-session motivational intervention adapted for young adults with psychosis (CCU-P) achieved 92% completion and high satisfaction, using a nonjudgmental approach to provide science-based information about cannabis-psychosis interactions.
Quick Facts
What This Study Found
The Cannabis Check-Up for Psychosis (CCU-P) — a two-session motivational enhancement therapy intervention — demonstrated 92% completion rate (11 of 12 completed both sessions), high satisfaction ratings, and all participants said they would recommend it to others in Coordinated Specialty Care.
Key Numbers
12 participants in the pilot. 92% completed both sessions (11 of 12). All participants would recommend to others. Optimizations included psychosis-specific infographics on rehospitalization risk and harm reduction strategies.
How They Did This
One-arm pilot study with 12 young adults experiencing psychosis who were regular cannabis users enrolled in Coordinated Specialty Care. The intervention was optimized from the Teen Marijuana Check-Up using qualitative interview and focus group data, reviewed by a Stakeholder Advisory Board.
Why This Research Matters
Cannabis use is common among young adults with psychosis and associated with worse outcomes, but few effective interventions exist for this population. Most approaches are too confrontational. This nonjudgmental intervention respects autonomy while providing information to support informed choices.
The Bigger Picture
The cannabis-psychosis relationship is well-established, but telling young adults to 'just stop' doesn't work. Motivational approaches that present information neutrally and support self-directed decision-making may be more effective and better aligned with psychiatric rehabilitation principles.
What This Study Doesn't Tell Us
Very small pilot (n=12), no control group or cannabis use outcome data. Measured feasibility and acceptability, not efficacy. One-arm design cannot determine if the intervention actually changes behavior. Specific to Coordinated Specialty Care settings.
Questions This Raises
- ?Will CCU-P actually reduce cannabis use or related harms in a larger trial?
- ?Would the intervention work outside Coordinated Specialty Care?
- ?Could the nonjudgmental approach be adapted for other substances in psychosis populations?
Trust & Context
- Key Stat:
- Evidence Grade:
- Small feasibility pilot with no control group or efficacy outcomes, but strong acceptability data supporting progression to a larger trial.
- Study Age:
- Published 2025.
- Original Title:
- Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.
- Published In:
- Psychiatric rehabilitation journal, 48(4), 244-253 (2025)
- Authors:
- Walker, Denise D(6), Petros, Ryan(3), Bennett, Melanie(2), Tennison, Mackenzie, Monroe-DeVita, Maria
- Database ID:
- RTHC-07902
Evidence Hierarchy
Frequently Asked Questions
How does this differ from telling someone with psychosis to stop using cannabis?
Instead of demanding abstinence, CCU-P provides science-based information about cannabis-psychosis interactions through infographics and motivational interviewing, then supports the participant in making their own informed decisions — which research shows is more effective.
Does cannabis make psychosis worse?
Research shows cannabis use is associated with increased rehospitalization risk and recovery challenges in young adults with psychosis. This intervention presents that evidence nonjudgmentally so participants can weigh it against their reasons for use.
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Cite This Study
https://rethinkthc.com/research/RTHC-07902APA
Walker, Denise D; Petros, Ryan; Bennett, Melanie; Tennison, Mackenzie; Monroe-DeVita, Maria. (2025). Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.. Psychiatric rehabilitation journal, 48(4), 244-253. https://doi.org/10.1037/prj0000654
MLA
Walker, Denise D, et al. "Development of a motivational enhancement therapy cannabis-reduction intervention for young adults experiencing psychosis: A feasibility pilot study.." Psychiatric rehabilitation journal, 2025. https://doi.org/10.1037/prj0000654
RethinkTHC
RethinkTHC Research Database. "Development of a motivational enhancement therapy cannabis-r..." RTHC-07902. Retrieved from https://rethinkthc.com/research/walker-2025-development-of-a-motivational
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.