Veterans with PTSD used more cannabis at baseline and were slower to cut back after a quit attempt

Among 104 cannabis-dependent veterans, PTSD did not predict faster relapse, but those with PTSD used more cannabis at the start and reduced their use more slowly after quitting.

Bonn-Miller, Marcel O et al.·The American journal of drug and alcohol abuse·2015·Moderate EvidenceProspective Cohort
RTHC-00925Prospective CohortModerate Evidence2015RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Prospective Cohort
Evidence
Moderate Evidence
Sample
N=104

What This Study Found

Researchers followed 104 cannabis-dependent veterans through a self-guided quit attempt, assessing them weekly for the first month and then monthly through 6 months. Veterans with PTSD used more cannabis at baseline and showed a slower initial decline in use following their quit attempt.

However, PTSD diagnosis was not associated with the time to first lapse (any use after quitting) or the time to full relapse (return to regular use). The slower reduction pattern occurred even after accounting for alcohol and tobacco use, as well as co-occurring mood and anxiety disorders.

The findings suggest that PTSD does not necessarily make quitting cannabis harder in terms of relapse timing, but it does affect the trajectory of reduction, meaning veterans with PTSD may need more intensive early support.

Key Numbers

104 veterans studied. Mean age 50.9 years. PTSD was associated with higher baseline cannabis use and slower initial decline. PTSD was not associated with time to first lapse or relapse. Results held after controlling for alcohol, tobacco, mood, and anxiety disorders.

How They Did This

Prospective cohort study of 104 predominantly male, cannabis-dependent US veterans (mean age 50.9). Assessments occurred before a self-guided quit attempt, weekly for 4 weeks, and monthly through 6 months. Analyses controlled for alcohol and tobacco use and co-occurring psychiatric diagnoses.

Why This Research Matters

Understanding how PTSD affects cannabis cessation patterns helps tailor treatment approaches. The finding that PTSD slows early reduction without accelerating relapse suggests a window for targeted intervention during the first weeks of a quit attempt.

The Bigger Picture

Veterans with PTSD represent a large population with high rates of cannabis dependence. This study provides nuanced evidence that PTSD affects the pattern of quitting rather than making quitting impossible, which supports developing PTSD-specific cessation strategies rather than treating PTSD as a barrier.

What This Study Doesn't Tell Us

Self-guided quit attempt without structured treatment may not reflect outcomes with professional support. Predominantly male veteran sample limits generalizability. Cannabis use was self-reported. The relatively older sample (mean age 51) may not reflect younger veteran populations.

Questions This Raises

  • ?Would intensive early support during the first weeks after quitting improve outcomes for veterans with PTSD?
  • ?Does treating PTSD symptoms directly accelerate cannabis reduction?
  • ?Would these patterns differ in a younger veteran cohort?

Trust & Context

Key Stat:
PTSD slowed early cannabis reduction but did not predict relapse
Evidence Grade:
Prospective cohort study with 6 months of follow-up and statistical controls for confounders, but no randomized treatment condition.
Study Age:
Published in 2015 using data from US veterans.
Original Title:
The impact of posttraumatic stress disorder on cannabis quit success.
Published In:
The American journal of drug and alcohol abuse, 41(4), 339-44 (2015)
Database ID:
RTHC-00925

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Enrolls participants and follows them forward in time.

What do these levels mean? →

Frequently Asked Questions

Does PTSD make it harder to quit cannabis?

In this study, veterans with PTSD did not relapse faster, but they used more cannabis at the start and were slower to reduce their use in the early weeks after quitting. This suggests PTSD affects the pace of reduction rather than the ability to quit.

What kind of help do veterans with PTSD need to quit cannabis?

The findings suggest that veterans with PTSD may benefit from more intensive support during the early phase of a quit attempt, when their reduction in use is slower compared to veterans without PTSD.

Read More on RethinkTHC

Cite This Study

RTHC-00925·https://rethinkthc.com/research/RTHC-00925

APA

Bonn-Miller, Marcel O; Moos, Rudolf H; Boden, Matthew Tyler; Long, W Robert; Kimerling, Rachel; Trafton, Jodie A. (2015). The impact of posttraumatic stress disorder on cannabis quit success.. The American journal of drug and alcohol abuse, 41(4), 339-44. https://doi.org/10.3109/00952990.2015.1043209

MLA

Bonn-Miller, Marcel O, et al. "The impact of posttraumatic stress disorder on cannabis quit success.." The American journal of drug and alcohol abuse, 2015. https://doi.org/10.3109/00952990.2015.1043209

RethinkTHC

RethinkTHC Research Database. "The impact of posttraumatic stress disorder on cannabis quit..." RTHC-00925. Retrieved from https://rethinkthc.com/research/bonn-miller-2015-the-impact-of-posttraumatic

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.