Web-based cannabis reduction program worked for adults with ADHD symptoms, also reducing depression and anxiety

Adults screening positive for ADHD who used the CANreduce 2.0 web program reduced cannabis use by 11.5 days per month and showed significant improvements in depression, anxiety, and ADHD symptom severity.

Ahlers, Joachim et al.·Journal of medical Internet research·2022·Moderate EvidenceRandomized Controlled Trial
RTHC-03654Randomized Controlled TrialModerate Evidence2022RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Randomized Controlled Trial
Evidence
Moderate Evidence
Sample
N=94

What This Study Found

Both ADHD-positive (n=94) and ADHD-negative (n=273) groups significantly reduced cannabis use days, severity scores, anxiety, and depression. ADHD-positive users showed slightly larger reductions but the between-group difference was not significant. ADHD-positive users also showed decreased ADHD symptom scores.

Key Numbers

ADHD+: n=94, reduced 11.5 use days. ADHD-: n=273, reduced 8.5 use days. ADHD+ SDS reduction: 3.57. ADHD+ anxiety reduction: 4.31. ADHD+ depression reduction: 10.25. ADHD+ symptom reduction: 4.65. No between-group difference (p=.08).

How They Did This

Secondary analysis of a randomized controlled trial. Adults with weekly cannabis use completed the CANreduce 2.0 self-guided web intervention (6 weeks, based on MI and CBT). Compared outcomes between ADHD-positive and ADHD-negative screeners at 3-month follow-up.

Why This Research Matters

Adults with ADHD have much higher rates of cannabis use disorder, yet are often excluded from or underserved by treatment programs. This accessible web-based intervention shows promise for this underserved group.

The Bigger Picture

The finding that cannabis reduction also improved ADHD symptoms and mood suggests these conditions may be interconnected, and addressing one may help the others.

What This Study Doesn't Tell Us

Secondary subgroup analysis. ADHD screened not diagnosed. Self-reported outcomes. ADHD-positive users were less likely to complete consumption diaries. No long-term follow-up beyond 3 months.

Questions This Raises

  • ?Would ADHD-specific adaptations to the program improve outcomes further?
  • ?Is the ADHD symptom improvement a direct result of reduced cannabis use?

Trust & Context

Key Stat:
11.5-day reduction in monthly cannabis use for adults with ADHD symptoms
Evidence Grade:
RCT subgroup analysis with validated instruments, though secondary analysis and screening-based ADHD identification limit conclusions.
Study Age:
Published in 2022.
Original Title:
Cannabis Use in Adults Who Screen Positive for Attention Deficit/Hyperactivity Disorder: CANreduce 2.0 Randomized Controlled Trial Subgroup Analysis.
Published In:
Journal of medical Internet research, 24(4), e30138 (2022)
Database ID:
RTHC-03654

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled TrialGold standard for testing treatments
This study
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal Study

Participants are randomly assigned to treatment or placebo groups to test cause and effect.

What do these levels mean? →

Frequently Asked Questions

Can people with ADHD successfully reduce cannabis use?

Yes. In this study, adults with ADHD symptoms reduced cannabis use by about 11.5 days per month using a self-guided web program, with improvements also seen in ADHD symptoms and mood.

Did reducing cannabis help ADHD symptoms?

ADHD symptom scores significantly decreased alongside cannabis reduction, though the study cannot determine if cannabis reduction directly caused the ADHD improvement.

Read More on RethinkTHC

Cite This Study

RTHC-03654·https://rethinkthc.com/research/RTHC-03654

APA

Ahlers, Joachim; Baumgartner, Christian; Augsburger, Mareike; Wenger, Andreas; Malischnig, Doris; Boumparis, Nikolaos; Berger, Thomas; Stark, Lars; Ebert, David D; Haug, Severin; Schaub, Michael P. (2022). Cannabis Use in Adults Who Screen Positive for Attention Deficit/Hyperactivity Disorder: CANreduce 2.0 Randomized Controlled Trial Subgroup Analysis.. Journal of medical Internet research, 24(4), e30138. https://doi.org/10.2196/30138

MLA

Ahlers, Joachim, et al. "Cannabis Use in Adults Who Screen Positive for Attention Deficit/Hyperactivity Disorder: CANreduce 2.0 Randomized Controlled Trial Subgroup Analysis.." Journal of medical Internet research, 2022. https://doi.org/10.2196/30138

RethinkTHC

RethinkTHC Research Database. "Cannabis Use in Adults Who Screen Positive for Attention Def..." RTHC-03654. Retrieved from https://rethinkthc.com/research/ahlers-2022-cannabis-use-in-adults

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.