Surgeons need to know their patients use cannabis because it affects every phase of surgical care

Cannabis use affects preoperative counseling, anesthesia dosing, postoperative pain and nausea, wound healing, and drug interactions with common surgical medications, yet most patients do not disclose use to their surgeons.

Mims, Mark M et al.·JAMA otolaryngology-- head & neck surgery·2024·Moderate EvidenceReview
RTHC-05555ReviewModerate Evidence2024RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Review
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Cannabis users may require higher anesthesia doses due to tolerance, face increased rates of myocardial ischemia, and experience prolonged sedation. Postoperative effects include potentially increased pain, nausea, and vomiting. Topical cannabinoids may improve wound healing. Significant drug interactions exist with anticoagulants. Cannabis use disorder is associated with increased perioperative morbidity and mortality.

Key Numbers

Higher anesthesia tolerance documented. Increased myocardial ischemia risk. Prolonged sedation effects. Significant drug interactions with anticoagulant medications. CUD associated with increased perioperative morbidity and mortality.

How They Did This

Clinical review published in JAMA Otolaryngology synthesizing evidence on how cannabis use affects surgical care phases, including preoperative, intraoperative, and postoperative considerations.

Why This Research Matters

With cannabis use rising and many patients not disclosing it, surgeons may be managing anesthesia, pain, and medications without knowing about a substance that affects all of these. The consequences range from inadequate anesthesia to dangerous drug interactions.

The Bigger Picture

Cannabis is no longer a niche concern in surgical medicine. As use becomes more common and legal, every surgical specialty needs protocols for screening, disclosure, and adjusted care plans for cannabis users.

What This Study Doesn't Tell Us

Review format with mixed-quality underlying evidence. Many effects described as potential or inconsistent across studies. Focused on otolaryngology context but findings apply broadly. Does not provide quantified risk estimates for most outcomes.

Questions This Raises

  • ?Should cannabis use be a standard preoperative screening question alongside tobacco and alcohol?
  • ?What is the optimal preoperative cannabis cessation period to minimize anesthesia complications?

Trust & Context

Key Stat:
cannabis use affects preoperative, intraoperative, and postoperative surgical care with clinically significant implications
Evidence Grade:
Published in JAMA Otolaryngology with comprehensive scope, though underlying evidence quality varies and many associations lack consistent support.
Study Age:
2024 publication.
Original Title:
Surgery-Related Considerations in Treating People Who Use Cannabis: A Review.
Published In:
JAMA otolaryngology-- head & neck surgery, 150(10), 918-924 (2024)
Database ID:
RTHC-05555

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research on a topic.

What do these levels mean? →

Frequently Asked Questions

Should I stop using cannabis before surgery?

The review suggests preoperative counseling for tapering cannabis use. Cannabis can increase anesthesia requirements, affect heart function, interact with medications, and potentially affect pain management. Disclosure to your surgical team is important for safe care planning.

How does cannabis interact with surgical medications?

Cannabis, particularly CBD, inhibits enzymes that metabolize many drugs. The most clinically significant interactions in surgical settings involve anticoagulants (blood thinners), where cannabis can alter drug levels and increase bleeding or clotting risk.

Read More on RethinkTHC

Cite This Study

RTHC-05555·https://rethinkthc.com/research/RTHC-05555

APA

Mims, Mark M; Parikh, Aniruddha C; Sandhu, Zainab; DeMoss, Noah; Mhawej, Rachad; Queimado, Lurdes. (2024). Surgery-Related Considerations in Treating People Who Use Cannabis: A Review.. JAMA otolaryngology-- head & neck surgery, 150(10), 918-924. https://doi.org/10.1001/jamaoto.2024.2545

MLA

Mims, Mark M, et al. "Surgery-Related Considerations in Treating People Who Use Cannabis: A Review.." JAMA otolaryngology-- head & neck surgery, 2024. https://doi.org/10.1001/jamaoto.2024.2545

RethinkTHC

RethinkTHC Research Database. "Surgery-Related Considerations in Treating People Who Use Ca..." RTHC-05555. Retrieved from https://rethinkthc.com/research/mims-2024-surgeryrelated-considerations-in-treating

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.