Medical cannabis patients describe it as having fewer side effects than prescriptions but face stigma and dosing confusion

Medical cannabis cardholders viewed cannabis as having fewer side effects and better quality of life than prescription medications, but cited stigma, cost, and lack of dosing guidance as major barriers.

Mercurio, Alana et al.·Substance use & misuse·2019·Preliminary EvidenceQualitative Study
RTHC-02175QualitativePreliminary Evidence2019RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Qualitative Study
Evidence
Preliminary Evidence
Sample
N=25

What This Study Found

Three key themes emerged: (1) patients perceived cannabis as having fewer/better side effects and improving quality of life versus prescriptions, (2) patients used cannabis to supplement or replace other medications including opioids, and (3) stigma, travel restrictions, cost, and inability of providers to give dosing/strain guidance significantly limited use.

Key Numbers

25 participants (Rhode Island medical cannabis cardholders); 3 major themes identified; patients specifically mentioned opioid substitution as a primary use case.

How They Did This

Qualitative semi-structured interviews with 25 Rhode Island medical cannabis cardholders, with audio recording, verbatim transcription, and thematic coding.

Why This Research Matters

Patient perspectives reveal practical barriers that surveys miss. The inability of healthcare providers to give dosing guidance leaves patients to experiment on their own, potentially leading to suboptimal or unsafe use.

The Bigger Picture

The paradox of medical cannabis: patients view it positively and use it as medicine, but the medical system cannot treat it like medicine (no dosing guidance, no strain recommendations, stigma from providers). This gap may limit both safety and efficacy.

What This Study Doesn't Tell Us

Small qualitative sample (25) from one state. Self-selected medical cannabis users may have more positive views. No clinical outcome verification. Rhode Island policies may not generalize.

Questions This Raises

  • ?How can healthcare providers offer meaningful cannabis guidance within current regulatory constraints?
  • ?Would standardized dosing frameworks improve patient outcomes?

Trust & Context

Key Stat:
No dosing guidance available
Evidence Grade:
Preliminary: small qualitative study from one state.
Study Age:
Published in 2019.
Original Title:
Marijuana as a Substitute for Prescription Medications: A Qualitative Study.
Published In:
Substance use & misuse, 54(11), 1894-1902 (2019)
Database ID:
RTHC-02175

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Uses interviews or focus groups to understand experiences in depth.

What do these levels mean? →

Frequently Asked Questions

Do patients prefer medical cannabis over prescription drugs?

In this study, patients reported cannabis had fewer side effects and better quality of life than prescriptions, and several used it to reduce or replace opioids.

What barriers do medical cannabis patients face?

Key barriers included stigma, cost, inability to travel with cannabis across state lines, and healthcare providers being unable to advise on dosing, strains, or methods of use.

Read More on RethinkTHC

Cite This Study

RTHC-02175·https://rethinkthc.com/research/RTHC-02175

APA

Mercurio, Alana; Aston, Elizabeth R; Claborn, Kasey R; Waye, Katherine; Rosen, Rochelle K. (2019). Marijuana as a Substitute for Prescription Medications: A Qualitative Study.. Substance use & misuse, 54(11), 1894-1902. https://doi.org/10.1080/10826084.2019.1618336

MLA

Mercurio, Alana, et al. "Marijuana as a Substitute for Prescription Medications: A Qualitative Study.." Substance use & misuse, 2019. https://doi.org/10.1080/10826084.2019.1618336

RethinkTHC

RethinkTHC Research Database. "Marijuana as a Substitute for Prescription Medications: A Qu..." RTHC-02175. Retrieved from https://rethinkthc.com/research/mercurio-2019-marijuana-as-a-substitute

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.