All top YouTube videos on THC oil and skin cancer were misleading and low quality

An analysis of the 10 most-viewed YouTube videos on THC oil and skin cancer found all were poor quality, 90% had poor reliability, and all were classified as misleading, yet most top comments were favorable toward the content.

Mamo, Andrina et al.·JMIR dermatology·2021·Moderate EvidenceCross-Sectional
RTHC-03316Cross SectionalModerate Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

All 10 videos received the lowest possible Global Quality Scale score (1 = poor quality). Nine of 10 received a DISCERN score of 0 (poor reliability). All were classified as misleading. Despite this, 48% of top comments were favorable and 48% neutral, with only 4% unfavorable.

Key Numbers

10 most-viewed videos analyzed; 10/10 GQS score of 1 (poor); 9/10 DISCERN score of 0 (poor); 10/10 misleading; 48% favorable comments, 48% neutral, 4% unfavorable

How They Did This

Researchers analyzed the 10 most-viewed YouTube videos on THC oil and skin cancer using the Global Quality Scale, DISCERN score, and established useful/misleading criteria. Top comments were categorized as favorable, unfavorable, or neutral.

Why This Research Matters

Patients with skin cancer may encounter these popular videos and delay or forgo evidence-based treatment. The disconnect between poor information quality and overwhelmingly positive audience reception makes this a significant public health concern.

The Bigger Picture

This mirrors broader patterns of health misinformation on social media platforms. When the most popular content on a cancer treatment topic is uniformly misleading and audiences overwhelmingly approve, the potential for patient harm is significant.

What This Study Doesn't Tell Us

Only 10 videos analyzed. YouTube content changes rapidly. Comment analysis is limited in scope. Does not measure whether viewers actually changed treatment decisions.

Questions This Raises

  • ?Have platforms like YouTube taken any steps to flag misleading cancer treatment content?
  • ?Do patients who view these videos delay conventional treatment?
  • ?Would counter-messaging from dermatologists reach the same audiences?

Trust & Context

Key Stat:
100% of top THC/skin cancer YouTube videos were misleading
Evidence Grade:
Small but systematic content analysis using validated quality instruments, limited to a single platform and point in time.
Study Age:
Published in 2021.
Original Title:
Tetrahydrocannabinol and Skin Cancer: Analysis of YouTube Videos.
Published In:
JMIR dermatology, 4(1), e26564 (2021)
Database ID:
RTHC-03316

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Can THC oil cure skin cancer?

While some preclinical research has explored cannabinoids and cancer cells, there is no clinical evidence that topical THC oil treats skin cancer. All 10 popular YouTube videos making such claims were rated misleading by researchers.

Why were the comments so positive if the videos were wrong?

The study did not investigate why, but the disconnect between poor content quality and positive audience reception suggests viewers may lack the expertise to evaluate medical claims or may be drawn to alternative treatment narratives.

Read More on RethinkTHC

Cite This Study

RTHC-03316·https://rethinkthc.com/research/RTHC-03316

APA

Mamo, Andrina; Szeto, Mindy D; Mirhossaini, Roya; Fortugno, Andrew; Dellavalle, Robert P. (2021). Tetrahydrocannabinol and Skin Cancer: Analysis of YouTube Videos.. JMIR dermatology, 4(1), e26564. https://doi.org/10.2196/26564

MLA

Mamo, Andrina, et al. "Tetrahydrocannabinol and Skin Cancer: Analysis of YouTube Videos.." JMIR dermatology, 2021. https://doi.org/10.2196/26564

RethinkTHC

RethinkTHC Research Database. "Tetrahydrocannabinol and Skin Cancer: Analysis of YouTube Vi..." RTHC-03316. Retrieved from https://rethinkthc.com/research/mamo-2021-tetrahydrocannabinol-and-skin-cancer

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.