Using blunts during a cigarette quit attempt did not significantly reduce chances of quitting

Among 500 Black adults in a smoking cessation trial, those who used blunts (cannabis-tobacco wraps) had similar quit rates to non-blunt users at both 12 and 26 weeks, regardless of whether they received varenicline or placebo.

Lambart, Leah et al.·Addictive behaviors·2024·Moderate Evidencerandomized controlled trial
RTHC-05451Randomized controlled trialModerate Evidence2024RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
randomized controlled trial
Evidence
Moderate Evidence
Sample
N=300

What This Study Found

Of 500 participants, 75 (15%) reported blunt use during the study. Blunt users had similar odds of quitting at Week 12 (OR 0.68, 95% CI 0.31-1.5) and Week 26 (OR 0.84, 95% CI 0.38-1.87) as non-blunt users. There was no interaction between blunt use and varenicline treatment on cessation outcomes.

Key Numbers

500 participants (300 varenicline, 200 placebo); 75 (15%) used blunts; mean age 45.6; 42% female; quit odds at Week 12: OR 0.68 (95% CI 0.31-1.5); Week 26: OR 0.84 (95% CI 0.38-1.87); no treatment interaction

How They Did This

Secondary analysis of a double-blind, placebo-controlled RCT comparing varenicline (n = 300) to placebo (n = 200) for smoking cessation among Black adults. Blunt use was assessed at baseline and weeks 4, 8, 12, 16, and 26. Abstinence was verified by salivary cotinine.

Why This Research Matters

Blunt use has been a concern in cessation research because the nicotine in tobacco wraps could undermine quit attempts. This finding suggests blunt use may not be the barrier to quitting that clinicians feared.

The Bigger Picture

For Black adults who use blunts, this finding suggests they should not be excluded from or discouraged from cigarette cessation efforts. However, blunts still expose users to combusted tobacco products.

What This Study Doesn't Tell Us

Secondary analysis with relatively small blunt user subgroup (75); may be underpowered to detect meaningful differences; blunt use was not the primary study focus; cannot assess impact of blunt frequency or quantity; results specific to Black adults

Questions This Raises

  • ?Would targeting all combustible products (including blunts) simultaneously improve overall cessation?
  • ?Does blunt use change after cigarette cessation?

Trust & Context

Key Stat:
15% used blunts; quit odds were similar to non-blunt users
Evidence Grade:
Secondary analysis of a well-designed RCT with biochemical verification, but limited by small blunt user subgroup and potential lack of statistical power.
Study Age:
2024 study
Original Title:
The impact of blunt use on smoking abstinence among Black adults: Secondary analysis from randomized controlled smoking cessation clinical trial.
Published In:
Addictive behaviors, 148, 107877 (2024)
Database ID:
RTHC-05451

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

Did using blunts make it harder to quit cigarettes?

Not significantly. Participants who used blunts had similar quit rates at both 12 and 26 weeks compared to those who did not use blunts. The odds ratios (0.68 and 0.84) suggested a slight numeric disadvantage but did not reach statistical significance.

Did varenicline work differently for blunt users?

No. There was no interaction between blunt use and varenicline treatment, meaning the medication appeared to work similarly regardless of whether participants also used blunts during their quit attempt.

Read More on RethinkTHC

Cite This Study

RTHC-05451·https://rethinkthc.com/research/RTHC-05451

APA

Lambart, Leah; Nollen, Nicole L; Mayo, Matthew S; Funk, Olivia; Leavens, Eleanor; Cruvinel, Erica; Brown, Alexandra; Ahluwalia, Jasjit S; Sanderson Cox, Lisa. (2024). The impact of blunt use on smoking abstinence among Black adults: Secondary analysis from randomized controlled smoking cessation clinical trial.. Addictive behaviors, 148, 107877. https://doi.org/10.1016/j.addbeh.2023.107877

MLA

Lambart, Leah, et al. "The impact of blunt use on smoking abstinence among Black adults: Secondary analysis from randomized controlled smoking cessation clinical trial.." Addictive behaviors, 2024. https://doi.org/10.1016/j.addbeh.2023.107877

RethinkTHC

RethinkTHC Research Database. "The impact of blunt use on smoking abstinence among Black ad..." RTHC-05451. Retrieved from https://rethinkthc.com/research/lambart-2024-the-impact-of-blunt

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.