Cannabis Use Was Associated With Lower Odds of Complete Recovery From Cyclic Vomiting Syndrome
In a 15-year study of 455 CVS adults, only 19% fully recovered, and cannabis use was among the strongest negative predictors (OR 0.36).
Quick Facts
What This Study Found
Episodes dropped from 18 to 6.8/year, ER visits from 6.1 to 2, hospitalizations from 2.3 to 0.7. Only 19% had complete resolution. Cannabis use OR 0.36 (p = 0.0007) for resolution. 19 patients (4%) died.
Key Numbers
455 patients. Episodes: 18 to 6.8/year. Resolution: 19%. Cannabis OR: 0.36. 4% mortality.
How They Did This
Retrospective analysis of 455 CVS patients at a tertiary center, mean 47.4 months follow-up.
Why This Research Matters
Largest long-term adult CVS follow-up. Cannabis was one of the strongest negative predictors, raising questions about CHS overlap.
The Bigger Picture
The 4% mortality underscores CVS severity. Some patients labeled CVS may actually have CHS.
What This Study Doesn't Tell Us
Retrospective. Single center. Referral bias. Cannot distinguish CVS from CHS in all cases.
Questions This Raises
- ?How many CVS patients actually have CHS?
- ?Would cannabis cessation improve CVS outcomes?
Trust & Context
- Key Stat:
- Cannabis use: 64% lower odds of complete CVS resolution
- Evidence Grade:
- Large retrospective cohort with multivariable analysis, subject to referral bias.
- Study Age:
- Published 2023.
- Original Title:
- Clinical characteristics and long-term outcomes in patients with cyclic vomiting syndrome: A 15-year experience at a tertiary referral center.
- Published In:
- Neurogastroenterology and motility, 35(7), e14571 (2023)
- Authors:
- Partovi, Omeed, Patel, Milan, Kovacic, Katja, Petrova, Ana, Garacchi, Zhuping, Venkatesan, Thangam
- Database ID:
- RTHC-04836
Evidence Hierarchy
Looks back at existing records to find patterns.
What do these levels mean? →Frequently Asked Questions
Does cannabis affect CVS outcomes?
Cannabis use was one of the strongest negative predictors of complete resolution, with 64% lower odds.
Can adults recover from CVS?
Most improved with specialized care, but only 19% fully recovered. 4% died.
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Cite This Study
https://rethinkthc.com/research/RTHC-04836APA
Partovi, Omeed; Patel, Milan; Kovacic, Katja; Petrova, Ana; Garacchi, Zhuping; Venkatesan, Thangam. (2023). Clinical characteristics and long-term outcomes in patients with cyclic vomiting syndrome: A 15-year experience at a tertiary referral center.. Neurogastroenterology and motility, 35(7), e14571. https://doi.org/10.1111/nmo.14571
MLA
Partovi, Omeed, et al. "Clinical characteristics and long-term outcomes in patients with cyclic vomiting syndrome: A 15-year experience at a tertiary referral center.." Neurogastroenterology and motility, 2023. https://doi.org/10.1111/nmo.14571
RethinkTHC
RethinkTHC Research Database. "Clinical characteristics and long-term outcomes in patients ..." RTHC-04836. Retrieved from https://rethinkthc.com/research/partovi-2023-clinical-characteristics-and-longterm
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.