A 24-year-old daily cannabis user who fasted appropriately before surgery still had 500 mL of gastric contents, raising concerns that THC-induced gastroparesis may create hidden aspiration risks.
Anesthesiologists, surgeons, daily cannabis users planning surgery, perioperative medicine professionals
500 mL of gastric contents found despite proper pre-surgical fasting
What the researchers found
Despite standard fasting (last meal at 10 PM the prior night), a daily cannabis user had 150 cc of gastric contents fill the airway device upon anesthesia induction, with 500 cc total suctioned from the stomach. The patient was asymptomatic for gastroparesis beforehand.
Why it matters
Standard pre-surgical fasting guidelines assume normal gastric emptying. If chronic cannabis use causes asymptomatic gastroparesis, current fasting protocols may be insufficient for daily users.
The numbers in context
Age 24; BMI 22; daily marijuana use; last meal at 10 PM; 150 cc filled the airway device; 500 cc clear gastric contents suctioned from stomach; no aspiration into lungs; uneventful recovery
How the study worked
Case report of a 24-year-old male daily cannabis user who presented for elective orthopedic surgery and experienced near-aspiration during anesthesia induction.
What this study cannot tell us
Single case report cannot establish incidence. No gastric emptying study was performed. The relationship between cannabis dose, chronicity, and gastroparesis risk is unknown. Other causes of delayed emptying were not fully ruled out.
How to read the evidence
Single case report raising a safety concern without established incidence data
When this study was published
Published in 2021. The incidence of THC-induced gastroparesis in surgical patients has not been studied.
The bigger picture
This case raises a systemic question: should anesthesiologists modify their approach for the millions of daily cannabis users undergoing surgery, given the potential for unrecognized gastroparesis?
Questions still open
- Should pre-operative screening ask about cannabis use? What percentage of daily cannabis users have subclinical gastroparesis? Should fasting guidelines be extended for chronic cannabis users?
Common questions
Can cannabis affect surgery safety?
Should cannabis users tell their anesthesiologist?
Read the original research
A Reason to Rethink Fasting Guidelines? Marijuana-Induced Gastroparesis and the Implications for Aspiration Risk in the Nil Per Os (NPO) Patient: A Case Report.
The American journal of case reports, 22, e934187
Citation
Cammarano, Caitlin A; Villaluz, Joseph Evan. (2021). A Reason to Rethink Fasting Guidelines? Marijuana-Induced Gastroparesis and the Implications for Aspiration Risk in the Nil Per Os (NPO) Patient: A Case Report.. The American journal of case reports, 22, e934187. https://doi.org/10.12659/AJCR.934187
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