An 18-year-old with CHS developed dangerous phosphorus depletion from severe vomiting
An 18-year-old daily cannabis user with cannabinoid hyperemesis syndrome developed severe and rapidly changing hypophosphatemia, a potentially dangerous electrolyte disturbance from prolonged vomiting.
Quick Facts
What This Study Found
An 18-year-old male with daily cannabis use presented with CHS and developed severe hypophosphatemia (low blood phosphorus) that changed rapidly, requiring careful monitoring and correction. This electrolyte disturbance is a less recognized but potentially serious CHS complication.
Key Numbers
18-year-old male with daily, prolonged cannabis use. Severe and rapidly changing hypophosphatemia documented during CHS episode.
How They Did This
Single case report documenting clinical presentation, laboratory findings, and management of severe hypophosphatemia in an 18-year-old with CHS and daily cannabis use.
Why This Research Matters
CHS-related vomiting can cause electrolyte disturbances beyond the commonly checked sodium and potassium. Hypophosphatemia can cause muscle weakness, respiratory failure, and cardiac dysfunction if unrecognized.
The Bigger Picture
As CHS becomes more common, the full spectrum of its complications is still being mapped. Electrolyte monitoring in CHS should be comprehensive, not limited to the most commonly checked values.
What This Study Doesn't Tell Us
Single case report. Cannot determine how common hypophosphatemia is in CHS. Other factors (nutritional status, refeeding) may have contributed. No long-term follow-up reported.
Questions This Raises
- ?How often does clinically significant hypophosphatemia occur in CHS?
- ?Should phosphorus be routinely monitored in CHS presentations?
Trust & Context
- Key Stat:
- Severe, rapidly changing hypophosphatemia in 18-year-old CHS patient
- Evidence Grade:
- Single case report alerting clinicians to a specific complication. Cannot establish frequency.
- Study Age:
- Published 2023.
- Original Title:
- Severe and rapidly changing hypophosphatemia in cannabinoid hyperemesis syndrome: a case report.
- Published In:
- Oxford medical case reports, 2024(6), omae055 (2024)
- Authors:
- Acharya, Prakash, Mishra, Aakash, Kuikel, Sandip, Mishra, Aman, Rauniyar, Robin, Khanal, Kunjan, Nepal, Amit Sharma, Thapaliya, Sahil
- Database ID:
- RTHC-05061
Evidence Hierarchy
Describes what happened to one person or a small group.
What do these levels mean? →Frequently Asked Questions
What electrolyte problems can CHS cause?
The severe vomiting in CHS can deplete multiple electrolytes. This case highlights hypophosphatemia (low phosphorus), which is less commonly checked than sodium or potassium but can cause serious complications including muscle weakness, breathing problems, and heart rhythm disturbances.
How serious is hypophosphatemia?
Severe hypophosphatemia can be life-threatening. Phosphorus is essential for cellular energy production, muscle function, and many metabolic processes. When levels drop severely, it can cause respiratory failure, cardiac dysfunction, and confusion. It requires careful, gradual correction.
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Cite This Study
https://rethinkthc.com/research/RTHC-05061APA
Acharya, Prakash; Mishra, Aakash; Kuikel, Sandip; Mishra, Aman; Rauniyar, Robin; Khanal, Kunjan; Nepal, Amit Sharma; Thapaliya, Sahil. (2024). Severe and rapidly changing hypophosphatemia in cannabinoid hyperemesis syndrome: a case report.. Oxford medical case reports, 2024(6), omae055. https://doi.org/10.1093/omcr/omae055
MLA
Acharya, Prakash, et al. "Severe and rapidly changing hypophosphatemia in cannabinoid hyperemesis syndrome: a case report.." Oxford medical case reports, 2024. https://doi.org/10.1093/omcr/omae055
RethinkTHC
RethinkTHC Research Database. "Severe and rapidly changing hypophosphatemia in cannabinoid ..." RTHC-05061. Retrieved from https://rethinkthc.com/research/acharya-2024-severe-and-rapidly-changing
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.