Youth Cannabis Use Is Shaped by Individual, Family, Peer, Community, and Policy Factors at Every Level

A systematic review of 15 U.S. studies found that cannabis use in youth aged 12-26 is driven by multi-level factors, from individual perceived risk and peer influence to neighborhood stress and cannabis legalization.

Phares, Belinda A et al.·Comprehensive child and adolescent nursing·2025·Strong EvidenceSystematic Review
RTHC-07366Systematic ReviewStrong Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Systematic Review
Evidence
Strong Evidence
Sample
Not reported

What This Study Found

Risk factors operated at every level: individual (older age, early initiation, low perceived harm, polysubstance use), interpersonal (peer influence, parental acceptance, family structure), community (neighborhood stress, social media, proximity to dispensaries), and societal (legalization, lower SES). Protective factors included peer disapproval, parental monitoring, school connectedness, and extracurricular involvement. Gender disparities in use are narrowing.

Key Numbers

15 studies meeting inclusion criteria. Risk factors at 4 levels: individual, interpersonal, community, societal. Key protective factors: peer disapproval, parental monitoring, school connectedness, extracurricular involvement. Gender use gap narrowing. Youth ages 12-26.

How They Did This

Systematic review searching CINAHL, Medline (OVID), and PubMed (January 2019-September 2024) using PRISMA guidelines. 15 peer-reviewed, quantitative, U.S.-based studies of youth ages 12-26 met inclusion criteria. Analysis was guided by the Social Ecological Model.

Why This Research Matters

Effective cannabis prevention requires understanding that youth use is not driven by any single factor. This review maps the full landscape of influences using the Social Ecological Model, providing a framework for designing multi-level interventions rather than relying on individual-focused approaches alone.

The Bigger Picture

As cannabis legalization expands, prevention efforts need to evolve beyond individual-focused messaging. This review demonstrates that effective prevention must address peer norms, family dynamics, community environments, and policy contexts simultaneously. The narrowing gender gap suggests prevention programs should equally target males and females.

What This Study Doesn't Tell Us

Only 15 studies met criteria, limiting the comprehensiveness of each ecological level. U.S.-only studies may not generalize internationally. Search limited to three databases. Studies from 2019-2024 reflect a specific policy era. Cannot determine the relative importance of different risk/protective factors.

Questions This Raises

  • ?Which ecological level offers the greatest leverage for reducing youth cannabis use?
  • ?How effective are multi-level interventions compared to single-level approaches?
  • ?Do the same risk and protective factors apply in states that have not legalized cannabis?

Trust & Context

Key Stat:
Risk and protective factors identified at individual, family, community, and policy levels
Evidence Grade:
Strong evidence from a well-conducted systematic review using PRISMA guidelines and a validated theoretical framework, though limited by the number of included studies.
Study Age:
2025 systematic review covering U.S. studies from 2019-2024.
Original Title:
Multilevel Risk and Protective Factors Influencing Cannabis Use Among Adolescents and Young Adults in the United States: A Systematic Review.
Published In:
Comprehensive child and adolescent nursing, 48(4), 278-306 (2025)
Database ID:
RTHC-07366

Evidence Hierarchy

Meta-Analysis / Systematic ReviewCombines many studies into one answer
This study
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal Study

Analyzes all available research on a topic using a structured method.

What do these levels mean? →

Frequently Asked Questions

What protects youth from cannabis use?

The strongest protective factors were peer disapproval of cannabis, parental monitoring, school connectedness, and involvement in extracurricular activities. These factors operate at different levels, suggesting prevention needs to address multiple influences simultaneously.

Does living near a dispensary increase youth use?

Yes, proximity to cannabis dispensaries was identified as a community-level risk factor. Other community factors included neighborhood stress and social media exposure to cannabis content.

Read More on RethinkTHC

Cite This Study

RTHC-07366·https://rethinkthc.com/research/RTHC-07366

APA

Phares, Belinda A; Driskill, Christie N; Basani, HimaBindu; Rodil, Aimee Rousella M; Barr, Emily Anne. (2025). Multilevel Risk and Protective Factors Influencing Cannabis Use Among Adolescents and Young Adults in the United States: A Systematic Review.. Comprehensive child and adolescent nursing, 48(4), 278-306. https://doi.org/10.1080/24694193.2025.2524680

MLA

Phares, Belinda A, et al. "Multilevel Risk and Protective Factors Influencing Cannabis Use Among Adolescents and Young Adults in the United States: A Systematic Review.." Comprehensive child and adolescent nursing, 2025. https://doi.org/10.1080/24694193.2025.2524680

RethinkTHC

RethinkTHC Research Database. "Multilevel Risk and Protective Factors Influencing Cannabis ..." RTHC-07366. Retrieved from https://rethinkthc.com/research/phares-2025-multilevel-risk-and-protective

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.