A synthetic marijuana user developed severe blood clotting failure and cardiac arrest from hidden rat poison

A case report documents severe disseminated intravascular coagulopathy (DIC) and cardiac arrest in a synthetic cannabinoid user, traced to brodifacoum (rat poison) contamination, adding to the growing epidemic of unintentional poisoning.

Chan, Abigail et al.·Journal of hematology·2019·Preliminary EvidenceCase Report
RTHC-01974Case ReportPreliminary Evidence2019RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Case Report
Evidence
Preliminary Evidence
Sample
Not reported

What This Study Found

The patient developed severe coagulopathy and cardiac arrest after synthetic cannabinoid use contaminated with brodifacoum. The case illustrates the life-threatening potential of contaminated synthetic cannabinoid products and the difficulty of detection through standard drug screening.

Key Numbers

Severe coagulopathy documented. Cardiac arrest occurred. Brodifacoum identified as the contaminant. Standard drug screening unable to detect synthetic cannabinoids.

How They Did This

Single case report documenting the clinical presentation, workup, and management of DIC and cardiac arrest secondary to brodifacoum-contaminated synthetic cannabinoid use.

Why This Research Matters

This case adds to the mounting evidence of a synthetic cannabinoid contamination crisis. Unlike previous reports focusing on bleeding, this case involved both DIC and cardiac arrest, demonstrating the extreme end of the toxicity spectrum.

The Bigger Picture

Each case of synthetic cannabinoid contamination reinforces the public health argument that unregulated drug markets create dangers that would not exist with regulated products. The brodifacoum contamination pattern has been documented across multiple US states.

What This Study Doesn't Tell Us

Single case report. Cannot determine how common this specific presentation is. The mechanism by which brodifacoum contaminates synthetic cannabinoid products remains unclear.

Questions This Raises

  • ?How widespread is brodifacoum contamination of synthetic cannabinoids?
  • ?Would expanded legalization of natural cannabis reduce synthetic cannabinoid use?
  • ?How can emergency departments better screen for this toxicity?

Trust & Context

Key Stat:
DIC + cardiac arrest
Evidence Grade:
Rated preliminary because this is a single case report.
Study Age:
Published in 2019.
Original Title:
Disseminated Intravascular Coagulopathy Secondary to Unintentional Brodifacoum Poisoning via Synthetic Marijuana.
Published In:
Journal of hematology, 8(1), 40-43 (2019)
Database ID:
RTHC-01974

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal StudyOne case or non-human subjects
This study

Describes what happened to one person or a small group.

What do these levels mean? →

Frequently Asked Questions

How did synthetic marijuana cause a cardiac arrest?

The synthetic cannabinoid product was contaminated with brodifacoum (rat poison), causing severe blood clotting dysfunction that led to DIC and ultimately cardiac arrest.

Can you test for synthetic cannabinoid contamination?

Standard drug screens do not detect synthetic cannabinoids, and brodifacoum testing requires specific laboratory analysis. This makes identification challenging in the emergency setting.

Read More on RethinkTHC

Cite This Study

RTHC-01974·https://rethinkthc.com/research/RTHC-01974

APA

Chan, Abigail; Adashek, Michael; Kang, Julian; Medina, Adriana. (2019). Disseminated Intravascular Coagulopathy Secondary to Unintentional Brodifacoum Poisoning via Synthetic Marijuana.. Journal of hematology, 8(1), 40-43. https://doi.org/10.14740/jh486

MLA

Chan, Abigail, et al. "Disseminated Intravascular Coagulopathy Secondary to Unintentional Brodifacoum Poisoning via Synthetic Marijuana.." Journal of hematology, 2019. https://doi.org/10.14740/jh486

RethinkTHC

RethinkTHC Research Database. "Disseminated Intravascular Coagulopathy Secondary to Uninten..." RTHC-01974. Retrieved from https://rethinkthc.com/research/chan-2019-disseminated-intravascular-coagulopathy-secondary

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.