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Study breakdown

Unintentional cannabis ingestion in children can cause coma and respiratory depression

ReviewModerate evidence
The takeaway

As cannabis legalization expands, unintentional pediatric cannabis ingestions are rising, with children potentially experiencing encephalopathy, coma, and respiratory depression from cannabis-containing products.

Parents, pediatricians, emergency physicians, and policymakers.

Cannabis can cause coma and respiratory depression in children

What the researchers found

Unintentional cannabis ingestions in children can cause significant toxicity including encephalopathy, coma, and respiratory depression. ED visits and poison control calls for pediatric cannabis exposure are rising in states with liberalized cannabis laws. Cannabis-containing products (edibles) are a particular risk for young children.

Why it matters

Pediatric clinicians in legalized states need to recognize cannabis toxicity quickly, as the presentation (altered mental status, respiratory depression) can mimic more serious conditions.

The numbers in context

No specific pooled statistics. Review synthesized trends in pediatric cannabis exposure data from multiple sources.

How the study worked

Narrative review of pediatric acute cannabis toxicity, covering recognition, evaluation, management, and counseling approaches.

What this study cannot tell us

Narrative review. Does not provide specific prevalence or incidence data. Focused on acute toxicity, not long-term effects.

How to read the evidence

Narrative review providing clinical guidance based on accumulated case data and expert opinion.

When this study was published

2019 review.

The bigger picture

The shift toward edible cannabis products creates particular risk for young children, who may mistake cannabis gummies, chocolates, or baked goods for regular food.

Questions still open

  • Are current child-resistant packaging requirements adequate? Should cannabis edibles be required to look distinct from regular food products?

Common questions

What happens if a child accidentally eats cannabis edibles?
Children can experience significant toxicity including altered mental status (encephalopathy), coma, and respiratory depression from unintentional cannabis ingestion.
Are pediatric cannabis exposures increasing?
Yes, ED visits and poison control calls for unintentional pediatric cannabis exposure are rising in states that have liberalized cannabis laws.

Read the original research

Acute Cannabis Toxicity.

Pediatric emergency care, 35(11), 799-804

Citation

Wong, Kei U; Baum, Carl R. (2019). Acute Cannabis Toxicity.. Pediatric emergency care, 35(11), 799-804. https://doi.org/10.1097/PEC.0000000000001970

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