Web-App Prevention Program Reduced Cannabis Use in Diverse College Students

A culturally sensitive web-app prevention program reduced cannabis use incidence and improved substance knowledge among diverse college students at a Hispanic Serving Institution.

Rainisch, Bethany K W et al.·Evaluation & the health professions·2025·Moderate EvidenceRandomized Controlled Trial
RTHC-07430Randomized Controlled TrialModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Randomized Controlled Trial
Evidence
Moderate Evidence
Sample
N=1,066

What This Study Found

Among 1,066 students randomly assigned to a web-app intervention, comparison, or control condition, those in the 5-module web-app group had significantly greater substance knowledge gains, more accurate peer use perceptions, and better understanding of health risks than comparison or control students. Web-app students also had lower incidence rates of cannabis use at program exit, with effects persisting at 90-day follow-up.

Key Numbers

1,066 participants. Three conditions: web-app, comparison, control. Cannabis use reduction at exit and 90-day follow-up. Significant improvements in substance knowledge, peer norm accuracy, and health risk perception. Hispanic Serving Institution in Southern California.

How They Did This

Randomized controlled trial with 1,066 participants at a Hispanic Serving Institution in southern California. Students were randomly assigned to control, comparison, or 5-module web-app condition. Surveys assessed knowledge, perceived health risks, normative peer use, and past 30-day substance use at baseline, exit, and 90-day follow-up.

Why This Research Matters

First-generation, working, and ethnic minority college students are underrepresented in substance use prevention research. This study demonstrates that a culturally sensitive digital intervention can effectively reach these populations and produce lasting reductions in cannabis use, filling a critical gap in prevention science.

The Bigger Picture

Digital prevention tools can scale to reach populations that traditional programs miss. The success of this web-app among first-generation and minority students suggests that culturally adapted digital interventions could be a cost-effective strategy for reducing substance use disparities.

What This Study Doesn't Tell Us

Single institution in Southern California. Self-reported substance use. 90-day follow-up is relatively short for assessing lasting behavior change. Cannot determine which specific modules drove the effects. Nicotine use reduction did not persist at follow-up.

Questions This Raises

  • ?Would the effects persist beyond 90 days?
  • ?Which specific program modules were most effective?
  • ?Could the web-app be adapted for other demographic groups or settings?

Trust & Context

Key Stat:
1,066 students randomized across 3 conditions
Evidence Grade:
Moderate: randomized design with large sample and follow-up, though single-institution and relatively short follow-up period.
Study Age:
2025 study
Original Title:
Evaluation of iSTART: A Novel Substance Use Prevention Web-App Designed for Diverse College Students.
Published In:
Evaluation & the health professions, 48(2), 163-173 (2025)
Database ID:
RTHC-07430

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled TrialGold standard for testing treatments
This study
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal Study

Participants are randomly assigned to treatment or placebo groups to test cause and effect.

What do these levels mean? →

Frequently Asked Questions

Can a phone app reduce cannabis use in college students?

This 5-module web-app significantly reduced cannabis use and improved substance knowledge among diverse college students, with effects lasting at 90-day follow-up.

Did the program work for minority students?

Yes. The program was specifically designed for and tested at a Hispanic Serving Institution with first-generation and ethnic minority students, showing effectiveness in a population typically underserved by prevention programs.

Read More on RethinkTHC

Cite This Study

RTHC-07430·https://rethinkthc.com/research/RTHC-07430

APA

Rainisch, Bethany K W; Dahlman, Linn; Shahverdi, Abnous; Alhassan, Sarah; Forster, Myriam. (2025). Evaluation of iSTART: A Novel Substance Use Prevention Web-App Designed for Diverse College Students.. Evaluation & the health professions, 48(2), 163-173. https://doi.org/10.1177/01632787251322996

MLA

Rainisch, Bethany K W, et al. "Evaluation of iSTART: A Novel Substance Use Prevention Web-App Designed for Diverse College Students.." Evaluation & the health professions, 2025. https://doi.org/10.1177/01632787251322996

RethinkTHC

RethinkTHC Research Database. "Evaluation of iSTART: A Novel Substance Use Prevention Web-A..." RTHC-07430. Retrieved from https://rethinkthc.com/research/rainisch-2025-evaluation-of-istart-a

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.