Pediatricians' Guide to Cannabis in Adolescents: Screening, Syndromes, and Treatment
A clinical review found less than 20% of U.S. youth currently use cannabis, with lifetime use actually decreasing over recent decades, while providing pediatricians with updated guidance on screening and treatment.
Quick Facts
What This Study Found
Despite increasing adult cannabis use and higher-THC products, longitudinal studies show less than 20% of youth report current cannabis use and lifetime use has actually decreased over recent decades. The review covers acute and chronic clinical syndromes, evidence-based screening tools, and treatment modalities specific to adolescents.
Key Numbers
Less than 20% of youth report current use. Lifetime use has decreased over recent decades. Almost half of U.S. states have legalized recreational adult use.
How They Did This
Clinical review published in Pediatrics in Review covering cannabis formulations, THC concentration variations, epidemiological trends in youth use, clinical syndromes (acute and chronic), evidence-based screening tools, and treatment approaches for adolescent cannabis use.
Why This Research Matters
The perception that teen cannabis use is exploding does not match the data. While more potent products are available and adult use has risen, adolescent use has not followed the same trajectory. This nuanced picture helps pediatricians calibrate their responses and focus on evidence-based screening and intervention.
The Bigger Picture
The disconnect between rising adult legalization and stable or declining youth use suggests that regulatory frameworks may be effectively limiting youth access, or that other social factors are at play. However, the increasing potency of available products means that youth who do use may face greater risks per use episode.
What This Study Doesn't Tell Us
Narrative clinical review without systematic methodology. Relies on existing epidemiological surveys that may have limitations. U.S.-focused. Does not quantify the impact of higher-potency products on the subset of youth who do use.
Questions This Raises
- ?Are youth who use cannabis today exposed to more risk per episode due to higher potency?
- ?Do current screening tools adequately capture emerging routes of use like vaping and dabbing?
- ?How should pediatrician messaging adapt as more states legalize?
Trust & Context
- Key Stat:
- Youth lifetime use has decreased over decades
- Evidence Grade:
- Moderate: published in a peer-reviewed clinical review journal drawing on epidemiological data, though not a systematic review.
- Study Age:
- 2025 study
- Original Title:
- Cannabis Use in Adolescents.
- Published In:
- Pediatrics in review, 46(9), 482-493 (2025)
- Authors:
- Rabinow, Lily, Dries, Emily, Hoffman, Neal D
- Database ID:
- RTHC-07422
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
Is teen cannabis use increasing with legalization?
Despite increasing adult legalization and availability, longitudinal studies show less than 20% of youth currently use cannabis and lifetime use has actually decreased over recent decades.
What should pediatricians know about cannabis?
The review covers different product formulations, varying THC concentrations, how to screen for use, common clinical syndromes to watch for, and evidence-based treatment approaches for adolescents.
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Cite This Study
https://rethinkthc.com/research/RTHC-07422APA
Rabinow, Lily; Dries, Emily; Hoffman, Neal D. (2025). Cannabis Use in Adolescents.. Pediatrics in review, 46(9), 482-493. https://doi.org/10.1542/pir.2024-006514
MLA
Rabinow, Lily, et al. "Cannabis Use in Adolescents.." Pediatrics in review, 2025. https://doi.org/10.1542/pir.2024-006514
RethinkTHC
RethinkTHC Research Database. "Cannabis Use in Adolescents." RTHC-07422. Retrieved from https://rethinkthc.com/research/rabinow-2025-cannabis-use-in-adolescents
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.