Young adult cannabis use increased more in states with full legalization than medical-only states

Cannabis and blunt use among young adults increased in all 16 studied states between 2002-2018, but increases were larger in states with adult-use laws compared to medical-only states, particularly after retail outlets opened.

Glasser, Allison M et al.·Cannabis (Albuquerque·2025·Moderate EvidenceObservational
RTHC-06548ObservationalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

All states showed declining cigarette smoking, slight cigar declines, and increasing cannabis and blunt use among young adults. Cannabis use increased following opening of medical retail outlets and further after adult-use implementation. In Maine, cannabis use increased 22.4% after medical retail opened and continued rising after adult use was adopted.

Key Numbers

16 states studied (2002-2018). Maine: 22.4% increase in cannabis use (95% CI: 19.0-29.4) after medical retail opened. All states showed declining cigarette use. Cannabis and blunt use increased more in AMU vs MUO states.

How They Did This

Segmented regression analysis of National Survey on Drug Use and Health data (2002-2018) in 16 states that passed adult and medical use or medical-only cannabis laws. Past 30-day cannabis, blunt, cigarette, and cigar use examined.

Why This Research Matters

This provides evidence that cannabis legalization, particularly the opening of retail outlets rather than just passing laws, is associated with increased young adult use. The simultaneous decline in cigarette smoking suggests shifting substance preferences rather than simply adding a new substance.

The Bigger Picture

The finding that retail outlet opening, not law passage, appears to drive use increases has important implications for states considering legalization. Implementation details (when and how products become available) may matter more than the legal change itself.

What This Study Doesn't Tell Us

Ecological study cannot prove individual-level causation. State-level trends are confounded by many other policy, economic, and cultural changes occurring simultaneously. NSDUH data may undercount some populations.

Questions This Raises

  • ?Does the increase in cannabis use among young adults translate to increased harm?
  • ?Could delayed retail outlet opening after legalization reduce the initial surge in use?

Trust & Context

Key Stat:
increase in young adult cannabis use in Maine after medical cannabis retail outlets opened
Evidence Grade:
National survey data with appropriate segmented regression, but ecological design and multiple confounding state-level factors limit causal claims.
Study Age:
2025 publication analyzing 2002-2018 data.
Original Title:
Temporal Trends in Young Adult Cannabis and Tobacco Use in States with Different Cannabis Policies.
Published In:
Cannabis (Albuquerque, N.M.), 8(2), 98-111 (2025)
Database ID:
RTHC-06548

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

Does legalization cause more young adults to use cannabis?

This study shows an association between legalization (especially retail sales) and increased use, but cannot prove causation. Many other factors changed simultaneously in these states. The increases were modest and cigarette use declined.

Why does retail opening matter more than the law itself?

Laws create legal permission, but retail outlets create physical access. When cannabis becomes as easy to purchase as alcohol, use appears to increase. States that passed laws but delayed retail implementation saw use increases primarily after stores opened.

Read More on RethinkTHC

Cite This Study

RTHC-06548·https://rethinkthc.com/research/RTHC-06548

APA

Glasser, Allison M; Uriarte, Caitlin; King Jensen, Jessica; Sterling, Kymberle; Shang, Ce; Hammond, David; Villanti, Andrea C. (2025). Temporal Trends in Young Adult Cannabis and Tobacco Use in States with Different Cannabis Policies.. Cannabis (Albuquerque, N.M.), 8(2), 98-111. https://doi.org/10.26828/cannabis/2025/000288

MLA

Glasser, Allison M, et al. "Temporal Trends in Young Adult Cannabis and Tobacco Use in States with Different Cannabis Policies.." Cannabis (Albuquerque, 2025. https://doi.org/10.26828/cannabis/2025/000288

RethinkTHC

RethinkTHC Research Database. "Temporal Trends in Young Adult Cannabis and Tobacco Use in S..." RTHC-06548. Retrieved from https://rethinkthc.com/research/glasser-2025-temporal-trends-in-young

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.