First reported case of marijuana-induced mania in an adolescent with no prior psychiatric history
A case report documented marijuana-induced manic symptoms in an adolescent with no prior psychiatric history, the first such report in this age group.
Quick Facts
What This Study Found
An adolescent with no known prior psychiatric history developed manic symptoms following marijuana use. Previous case reports of marijuana-induced mania had been documented only in adult patients.
The case was notable because the adolescent had no identifiable psychiatric vulnerability before the marijuana exposure. The report was contextualized against nationwide usage data showing 11.8% of 8th graders, 26.7% of 10th graders, and 32.8% of 12th graders had used marijuana at least once in the prior year.
Key Numbers
First documented adolescent case. Usage rates in 2009: 11.8% of 8th graders, 26.7% of 10th graders, 32.8% of 12th graders.
How They Did This
Case report with retrospective review of published literature on marijuana-induced mania. No psychiatric history identified in the patient prior to the marijuana-associated manic episode.
Why This Research Matters
The case extended the recognized age range for marijuana-induced mania to adolescents and suggested that even individuals without psychiatric vulnerabilities could develop acute manic symptoms.
The Bigger Picture
As cannabis use among adolescents remained prevalent, recognizing the potential for acute psychiatric emergencies including mania was important for emergency and pediatric clinicians.
What This Study Doesn't Tell Us
Single case report. Cannot establish causation or estimate how commonly marijuana triggers mania. Undetected pre-existing vulnerability is possible despite no identified psychiatric history.
Questions This Raises
- ?How often does marijuana trigger manic episodes in adolescents without known vulnerability?
- ?What biological mechanisms might explain marijuana-induced mania?
Trust & Context
- Key Stat:
- First reported adolescent case of marijuana-induced mania
- Evidence Grade:
- Single case report documenting a novel presentation but unable to establish prevalence or causation.
- Study Age:
- Published in 2011. Additional cases of cannabis-associated mania in adolescents have been reported since.
- Original Title:
- Marijuana-induced mania in a healthy adolescent: a case report.
- Published In:
- General hospital psychiatry, 33(6), 640.e3-4 (2011)
- Authors:
- Iskandar, Joseph W, Griffeth, Benjamin, Sharma, Taral
- Database ID:
- RTHC-00492
Evidence Hierarchy
Describes what happened to one person or a small group.
What do these levels mean? →Frequently Asked Questions
Can marijuana cause mania?
This case report documented an adolescent with no psychiatric history who developed manic symptoms after marijuana use. While rare, the case added to a growing list of reports of marijuana-triggered mania.
What is mania?
Mania is a state of abnormally elevated mood, energy, and activity, often accompanied by decreased need for sleep, racing thoughts, and impulsive behavior. It can occur in bipolar disorder or be triggered by substances.
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Cite This Study
https://rethinkthc.com/research/RTHC-00492APA
Iskandar, Joseph W; Griffeth, Benjamin; Sharma, Taral. (2011). Marijuana-induced mania in a healthy adolescent: a case report.. General hospital psychiatry, 33(6), 640.e3-4. https://doi.org/10.1016/j.genhosppsych.2011.04.007
MLA
Iskandar, Joseph W, et al. "Marijuana-induced mania in a healthy adolescent: a case report.." General hospital psychiatry, 2011. https://doi.org/10.1016/j.genhosppsych.2011.04.007
RethinkTHC
RethinkTHC Research Database. "Marijuana-induced mania in a healthy adolescent: a case repo..." RTHC-00492. Retrieved from https://rethinkthc.com/research/iskandar-2011-marijuanainduced-mania-in-a
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.