Psychotic-like experiences did not predict whether young adults quit or continued cannabis
Among 552 young cannabis users tracked from age 19 to 22, psychotic-like experiences were not associated with changes in cannabis use, but later age of first use predicted greater increases over time.
Quick Facts
What This Study Found
Mean cannabis use increased from age 19 to 22. Age of first cannabis use was positively associated with change in use between the two time points (later starters increased more). Psychotic-like experiences at either age were not significantly associated with changes in cannabis use.
Key Numbers
552 ever-users analyzed; nearly all (549) reported at least one psychotic-like experience at age 19; mean cannabis use increased from age 19 to 22; perceived stress was positively associated with psychotic experiences at age 22
How They Did This
Longitudinal study from the IMAGEN cohort, initially recruited at age 14 in European high schools. Among 552 ever-users of cannabis, psychotic-like experiences were measured with the Community Assessment of Psychic Experiences (CAPE) at ages 19 and 22, along with quantitative cannabis use data. Perceived stress was assessed at age 22.
Why This Research Matters
If psychotic-like experiences prompted people to quit cannabis, it could act as a natural protective mechanism. This study found no such self-correcting pattern, suggesting that experiencing psychotic symptoms does not reliably lead young users to reduce their consumption.
The Bigger Picture
The finding that psychotic-like experiences do not trigger cannabis reduction challenges the assumption that negative experiences naturally lead to behavior change. The stress-psychosis link independent of cannabis also highlights the complexity of psychosis risk.
What This Study Doesn't Tell Us
Only two time points (ages 19 and 22). Self-reported cannabis use and psychotic experiences. Nearly universal endorsement of at least one psychotic-like experience at age 19 limits variance. Perceived stress measured at only one time point.
Questions This Raises
- ?Why does later cannabis onset predict steeper increases in use?
- ?Could the stress-psychosis association be a stronger driver of psychotic experiences than cannabis itself in this age group?
Trust & Context
- Key Stat:
- 549 of 552 ever-users reported at least one psychotic-like experience by age 19
- Evidence Grade:
- Longitudinal design from a well-established European cohort, though limited to two time points with self-reported measures.
- Study Age:
- Published in 2021 using data from the IMAGEN study cohort.
- Original Title:
- Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?
- Published In:
- Schizophrenia research, 228, 271-279 (2021)
- Authors:
- Daedelow, Laura S, Banaschewski, Tobias(14), Berning, Moritz, Bokde, Arun L W, Brühl, Rüdiger, Burke Quinlan, Erin, Curran, H Valerie, Desrivières, Sylvane, Flor, Herta, Grigis, Antoine, Garavan, Hugh, Hardon, Anita, Kaminski, Jakob, Martinot, Jean-Luc, Paillère Martinot, Marie-Laure, Artiges, Eric, Murray, Hayley, Nees, Frauke, Oei, Nicole Y L, Papadopoulos Orfanos, Dimitri, Paus, Tomáš, Poustka, Luise, Hohmann, Sarah, Millenet, Sabina, Rosenthal, Annika, Fröhner, Juliane H, Smolka, Michael N, Walter, Henrik, Whelan, Robert, Wiers, Reinout W, Schumann, Gunter, Heinz, Andreas
- Database ID:
- RTHC-03081
Evidence Hierarchy
Follows a group of people over time to track how outcomes develop.
What do these levels mean? →Frequently Asked Questions
Did psychotic-like experiences cause young people to stop using cannabis?
No. The frequency of psychotic-like experiences at age 19 or 22 was not significantly associated with changes in cannabis use between those ages.
What predicted changes in cannabis use?
Age of first cannabis use was the significant predictor. Those who started later showed greater increases in use from age 19 to 22. Perceived stress was associated with psychotic experiences but not with cannabis use changes.
Read More on RethinkTHC
- THC-amygdala-anxiety-brain
- anandamide-weed-withdrawal
- cannabinoid-receptors-recovery-time
- cannabis-developing-brain-teenagers
- cant-enjoy-anything-without-weed
- dopamine-recovery-after-quitting-weed
- endocannabinoid-system-explained-simply
- endocannabinoid-system-withdrawal
- nervous-system-weed-withdrawal-fight-flight
- teen-weed-use-under-18-effects-brain
- thc-brain-withdrawal
- thc-prefrontal-cortex-brain-effects
- weed-cortisol-stress-hormones
- weed-memory-loss-recovery
- weed-motivation-amotivational-syndrome
- weed-nervous-system-effects
- weed-reward-system-brain
Cite This Study
https://rethinkthc.com/research/RTHC-03081APA
Daedelow, Laura S; Banaschewski, Tobias; Berning, Moritz; Bokde, Arun L W; Brühl, Rüdiger; Burke Quinlan, Erin; Curran, H Valerie; Desrivières, Sylvane; Flor, Herta; Grigis, Antoine; Garavan, Hugh; Hardon, Anita; Kaminski, Jakob; Martinot, Jean-Luc; Paillère Martinot, Marie-Laure; Artiges, Eric; Murray, Hayley; Nees, Frauke; Oei, Nicole Y L; Papadopoulos Orfanos, Dimitri; Paus, Tomáš; Poustka, Luise; Hohmann, Sarah; Millenet, Sabina; Rosenthal, Annika; Fröhner, Juliane H; Smolka, Michael N; Walter, Henrik; Whelan, Robert; Wiers, Reinout W; Schumann, Gunter; Heinz, Andreas. (2021). Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?. Schizophrenia research, 228, 271-279. https://doi.org/10.1016/j.schres.2021.01.002
MLA
Daedelow, Laura S, et al. "Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?." Schizophrenia research, 2021. https://doi.org/10.1016/j.schres.2021.01.002
RethinkTHC
RethinkTHC Research Database. "Are psychotic-like experiences related to a discontinuation ..." RTHC-03081. Retrieved from https://rethinkthc.com/research/daedelow-2021-are-psychoticlike-experiences-related
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.