27% of Women with HIV Used Cannabis, with Half Varying Their Use Frequency Over Time

Among 1,246 women with HIV, cannabis use was twice the national average, with smoking dominant (96%), half of users changing their frequency over 18 months, and 15% using daily.

Haley, Danielle F et al.·AIDS and behavior·2025·Moderate Evidencelongitudinal-study
RTHC-06614Longitudinal StudyModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
longitudinal-study
Evidence
Moderate Evidence
Sample
N=1,246

What This Study Found

In the Women's Interagency HIV Study (2018-2019), 27% of 1,246 women with HIV used cannabis and 15% used daily. Smoking was the dominant mode (96%), followed by edibles (30%) and vaping (18%). Notably, 50% of users reported varying use frequencies across time points, suggesting unstable use patterns. Cannabis users had significantly higher rates of alcohol (69% vs 37%), cigarette (61% vs 29%), and other drug use (16% vs 4%).

Key Numbers

1,246 women with HIV; median age 52; 65% Black/African American; 27% any cannabis use; 15% daily use; 96% smoked; 30% edibles; 18% vaped; 50% varied frequency; higher concurrent alcohol (69% vs 37%) and cigarette use (61% vs 29%)

How They Did This

Longitudinal analysis of 1,246 women with HIV in the WIHS over 18 months (2018-2019). Characterized prevalence, frequency, and modes of cannabis use. Compared demographics and health behaviors between users and non-users. Sankey diagrams illustrated transitions between use frequency categories.

Why This Research Matters

Women with HIV are an aging population where cannabis use is twice the national average. The finding that half of users change their frequency over time challenges assumptions about stable use patterns and has implications for how providers assess and discuss cannabis use.

The Bigger Picture

As women with HIV live longer due to effective antiretroviral therapy, understanding their substance use patterns becomes increasingly important for managing aging-related comorbidities and potential drug interactions.

What This Study Doesn't Tell Us

Single cohort of predominantly Black, low-income women with HIV; may not generalize. Self-report measures. 18-month window may not capture longer-term patterns. Cannot assess health outcomes associated with different use patterns.

Questions This Raises

  • ?How does cannabis use interact with antiretroviral medications in this population?
  • ?What drives the unstable use patterns, and do transitions to higher frequency predict health outcomes?

Trust & Context

Key Stat:
Evidence Grade:
Moderate: established longitudinal cohort with detailed use characterization, but single-study with specific demographics.
Study Age:
2025 publication using 2018-2019 data
Original Title:
Patterns of Cannabis Use among Women With HIV in the United States.
Published In:
AIDS and behavior, 29(6), 2022-2032 (2025)
Database ID:
RTHC-06614

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Read More on RethinkTHC

Cite This Study

RTHC-06614·https://rethinkthc.com/research/RTHC-06614

APA

Haley, Danielle F; Bullington, Brooke W; Tien, Phyllis; Knittel, Andrea K; Bobitt, Julie; Kempf, Mirjam-Colette; Philbin, Morgan; Hanna, David B; Lindsey, StarrLa'diamond; Kassaye, Seble; DeHovitz, Jack; Cohen, Mardge; Wingood, Gina; Jones, Deborah L; Williams, Michael P; Wang, Richard J; Edmonds, Andrew. (2025). Patterns of Cannabis Use among Women With HIV in the United States.. AIDS and behavior, 29(6), 2022-2032. https://doi.org/10.1007/s10461-025-04669-z

MLA

Haley, Danielle F, et al. "Patterns of Cannabis Use among Women With HIV in the United States.." AIDS and behavior, 2025. https://doi.org/10.1007/s10461-025-04669-z

RethinkTHC

RethinkTHC Research Database. "Patterns of Cannabis Use among Women With HIV in the United ..." RTHC-06614. Retrieved from https://rethinkthc.com/research/haley-2025-patterns-of-cannabis-use

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.