Pediatric Palliative Care Cannabis Clinic Saw Reduced Hospital Days and Medication Use

Children in a pediatric palliative care cannabis clinic showed fewer inpatient days, with 35% reducing or discontinuing other medications.

Free, Taylor et al.·Journal of palliative medicine·2025·Preliminary EvidenceRetrospective Cohort
RTHC-06483Retrospective CohortPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Retrospective Cohort
Evidence
Preliminary Evidence
Sample
N=46

What This Study Found

Among 46 pediatric palliative care patients (mean age 11.7), there was a significant decrease in inpatient days and cost. 35% reduced or discontinued other medications. Most common recommendation: 1:1 CBD:THC tincture. No significant adverse events.

Key Numbers

46 patients (mean age 11.7). 50% neurological, 37% oncological, 13% chronic pain. 35% reduced other medications. Significant decrease in inpatient days.

How They Did This

Retrospective chart review of 46 consecutive patients at a midwestern US pediatric hospital (2019-2022).

Why This Research Matters

Evidence for medical cannabis in pediatric palliative care is extremely limited. This real-world data suggests benefits with minimal adverse effects.

The Bigger Picture

If medical cannabis can reduce polypharmacy and hospital days in pediatric palliative care, it could shift the standard of care.

What This Study Doesn't Tell Us

Small sample. No control group. Single center. Cannot attribute improvements solely to cannabis.

Questions This Raises

  • ?Which pediatric conditions benefit most?
  • ?Would a controlled trial confirm reduced hospital days?

Trust & Context

Key Stat:
35% of pediatric patients reduced or discontinued other medications
Evidence Grade:
Small retrospective chart review without control group.
Study Age:
2025 study
Original Title:
Characterizing the Population of a Medical Cannabis Clinic in a Pediatric Hospital.
Published In:
Journal of palliative medicine, 28(8), 1020-1028 (2025)
Database ID:
RTHC-06483

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Looks back at existing records to find patterns.

What do these levels mean? →

Frequently Asked Questions

What conditions were treated?

Half had neurological diagnoses, 37% cancer/blood disorders, 13% chronic pain.

What type of cannabis was used?

Most commonly a 1:1 CBD:THC tincture.

Read More on RethinkTHC

Cite This Study

RTHC-06483·https://rethinkthc.com/research/RTHC-06483

APA

Free, Taylor; Grossoehme, Daniel H; Richner, Gwendolyn; Brown, Miraides F; Friebert, Sarah. (2025). Characterizing the Population of a Medical Cannabis Clinic in a Pediatric Hospital.. Journal of palliative medicine, 28(8), 1020-1028. https://doi.org/10.1089/jpm.2024.0533

MLA

Free, Taylor, et al. "Characterizing the Population of a Medical Cannabis Clinic in a Pediatric Hospital.." Journal of palliative medicine, 2025. https://doi.org/10.1089/jpm.2024.0533

RethinkTHC

RethinkTHC Research Database. "Characterizing the Population of a Medical Cannabis Clinic i..." RTHC-06483. Retrieved from https://rethinkthc.com/research/free-2025-characterizing-the-population-of

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.