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Study breakdown

Cannabis and turmeric for IBD: promising but not ready to replace standard treatment

ReviewModerate evidence
The takeaway

Clinical trials suggest cannabinoids may help with IBD, IBS, nausea, and motility disorders, while turmeric shows promise as an IBD add-on treatment, but neither should replace standard therapy.

IBD patients interested in complementary therapies and gastroenterologists advising them.

Neither cannabis nor turmeric compared to standard IBD therapy

What the researchers found

Cannabinoids modulate gut motility and visceral pain and have anti-inflammatory properties. Clinical trials suggest a therapeutic role in IBD, IBS, nausea/vomiting, and GI motility disorders. Turmeric shows promise as adjuvant IBD treatment. Neither has been compared to standard IBD therapy. Reports of serious adverse effects from synthetic cannabinoids highlight safety concerns.

Why it matters

Many IBD patients already use these complementary therapies. This review helps clinicians understand what the evidence actually supports versus what remains unproven.

The numbers in context

Neither cannabis nor turmeric has been compared to standard IBD therapy. Synthetic cannabinoids have caused serious adverse effects.

How the study worked

Narrative review of the most recent studies on cannabis and turmeric for IBD and other intestinal diseases.

What this study cannot tell us

Narrative review. Limited clinical trial data for both cannabis and turmeric in IBD. No head-to-head comparisons with standard treatments.

How to read the evidence

Moderate: narrative review of emerging clinical trial data, limited by small number of trials.

When this study was published

Published in 2019.

The bigger picture

Complementary therapies for IBD are increasingly popular, but the gap between patient interest and clinical evidence remains wide. Cannabis may help with symptoms, but safety concerns with synthetic products add complexity.

Questions still open

  • What are the appropriate dosing and timing for cannabinoids in IBD? Could combining cannabis and turmeric provide synergistic benefits? Are there bleeding risks with synthetic cannabinoids in IBD patients?

Common questions

Can cannabis replace IBD medication?
No. This review notes that cannabis has not been compared to standard IBD treatments and should not be recommended as an alternative. It may help with symptoms alongside standard therapy.
Are synthetic cannabinoids safe for IBD?
The review highlights reports of serious adverse effects from synthetic cannabinoids, including potential bleeding complications. Natural cannabis products and synthetic ones may carry different risk profiles.

Read the original research

Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases.

Current gastroenterology reports, 21(2), 2

Citation

Quezada, Sandra M; Cross, Raymond K. (2019). Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases.. Current gastroenterology reports, 21(2), 2. https://doi.org/10.1007/s11894-019-0670-0

Explore the wider topic