THC was prescribed only to severely ill children in Vienna, with significant documentation gaps
A retrospective analysis of 32 pediatric patients prescribed THC at a Vienna tertiary center found it was used exclusively for severely ill children (average 9.4 diagnoses each), mostly in palliative contexts, with notable gaps in dosing and indication documentation.
Quick Facts
What This Study Found
The 32 pediatric patients who received THC had an average of 9.42 diagnoses and were treated with an average of 13.52 other drugs simultaneously. Brain cancer and genetic diseases were the most common diagnoses. Eleven of 32 patients (34%) died by the end of the study period, indicating predominantly palliative use. Significant gaps in documentation of indications, dosage, and treatment duration were identified.
Key Numbers
32 patients; mean 9.42 diagnoses per patient; mean 13.52 concurrent medications; brain cancer and genetic diseases most common; 11/32 (34%) died during study period
How They Did This
Retrospective data analysis of all THC prescriptions at the Department of Pediatrics and Adolescent Medicine, Medical University Vienna, from 2016-2018. Patient records reviewed for diagnoses, concurrent medications, and prescribing documentation.
Why This Research Matters
This study reveals both the extreme caution applied to pediatric THC prescribing (only the sickest patients) and the paradox that even in a controlled medical setting, prescribing documentation remains inadequate.
The Bigger Picture
The gap between the severity of illness in children receiving THC and the quality of documentation about their THC treatment represents a patient safety concern that needs addressing as pediatric cannabis medicine evolves.
What This Study Doesn't Tell Us
Single-center retrospective study. Very small sample of 32. Documentation gaps may reflect charting practices rather than actual prescribing quality. Austrian regulatory context may not generalize.
Questions This Raises
- ?Would standardized pediatric cannabis prescribing templates improve documentation?
- ?Is the restriction of THC to the sickest children appropriate, or are moderately ill children being undertreated?
Trust & Context
- Key Stat:
- 32 patients with an average of 9.4 diagnoses and 13.5 other medications each
- Evidence Grade:
- Single-center retrospective analysis providing descriptive data, but very small sample and documentation limitations constrain findings.
- Study Age:
- Published 2023 using 2016-2018 data
- Original Title:
- Tetrahydrocannabinol in Pediatrics: Room for Improvement?
- Published In:
- Medical cannabis and cannabinoids, 6(1), 125-129 (2023)
- Authors:
- de Gier, Charlotte, Scharinger, Christian, Stark, Rosa H, Steurer, Philipp, Klier, Claudia M
- Database ID:
- RTHC-04492
Evidence Hierarchy
Looks back at existing records to find patterns.
What do these levels mean? →Frequently Asked Questions
Which children receive medical THC?
In this Vienna hospital, only severely ill children received THC. They had an average of 9.4 diagnoses each, mostly brain cancer or genetic diseases, and a third died during the study period, indicating predominantly palliative use.
Is pediatric THC prescribing well documented?
Not in this study. Significant gaps in documentation of indications, dosage, and treatment duration were found, raising patient safety concerns.
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Cite This Study
https://rethinkthc.com/research/RTHC-04492APA
de Gier, Charlotte; Scharinger, Christian; Stark, Rosa H; Steurer, Philipp; Klier, Claudia M. (2023). Tetrahydrocannabinol in Pediatrics: Room for Improvement?. Medical cannabis and cannabinoids, 6(1), 125-129. https://doi.org/10.1159/000533607
MLA
de Gier, Charlotte, et al. "Tetrahydrocannabinol in Pediatrics: Room for Improvement?." Medical cannabis and cannabinoids, 2023. https://doi.org/10.1159/000533607
RethinkTHC
RethinkTHC Research Database. "Tetrahydrocannabinol in Pediatrics: Room for Improvement?" RTHC-04492. Retrieved from https://rethinkthc.com/research/de-2023-tetrahydrocannabinol-in-pediatrics-room
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.