THC was prescribed only to severely ill children in Vienna, with significant documentation gaps

A retrospective analysis of 32 pediatric patients prescribed THC at a Vienna tertiary center found it was used exclusively for severely ill children (average 9.4 diagnoses each), mostly in palliative contexts, with notable gaps in dosing and indication documentation.

de Gier, Charlotte et al.·Medical cannabis and cannabinoids·2023·Preliminary EvidenceRetrospective Cohort
RTHC-04492Retrospective CohortPreliminary Evidence2023RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Retrospective Cohort
Evidence
Preliminary Evidence
Sample
N=32

What This Study Found

The 32 pediatric patients who received THC had an average of 9.42 diagnoses and were treated with an average of 13.52 other drugs simultaneously. Brain cancer and genetic diseases were the most common diagnoses. Eleven of 32 patients (34%) died by the end of the study period, indicating predominantly palliative use. Significant gaps in documentation of indications, dosage, and treatment duration were identified.

Key Numbers

32 patients; mean 9.42 diagnoses per patient; mean 13.52 concurrent medications; brain cancer and genetic diseases most common; 11/32 (34%) died during study period

How They Did This

Retrospective data analysis of all THC prescriptions at the Department of Pediatrics and Adolescent Medicine, Medical University Vienna, from 2016-2018. Patient records reviewed for diagnoses, concurrent medications, and prescribing documentation.

Why This Research Matters

This study reveals both the extreme caution applied to pediatric THC prescribing (only the sickest patients) and the paradox that even in a controlled medical setting, prescribing documentation remains inadequate.

The Bigger Picture

The gap between the severity of illness in children receiving THC and the quality of documentation about their THC treatment represents a patient safety concern that needs addressing as pediatric cannabis medicine evolves.

What This Study Doesn't Tell Us

Single-center retrospective study. Very small sample of 32. Documentation gaps may reflect charting practices rather than actual prescribing quality. Austrian regulatory context may not generalize.

Questions This Raises

  • ?Would standardized pediatric cannabis prescribing templates improve documentation?
  • ?Is the restriction of THC to the sickest children appropriate, or are moderately ill children being undertreated?

Trust & Context

Key Stat:
32 patients with an average of 9.4 diagnoses and 13.5 other medications each
Evidence Grade:
Single-center retrospective analysis providing descriptive data, but very small sample and documentation limitations constrain findings.
Study Age:
Published 2023 using 2016-2018 data
Original Title:
Tetrahydrocannabinol in Pediatrics: Room for Improvement?
Published In:
Medical cannabis and cannabinoids, 6(1), 125-129 (2023)
Database ID:
RTHC-04492

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Looks back at existing records to find patterns.

What do these levels mean? →

Frequently Asked Questions

Which children receive medical THC?

In this Vienna hospital, only severely ill children received THC. They had an average of 9.4 diagnoses each, mostly brain cancer or genetic diseases, and a third died during the study period, indicating predominantly palliative use.

Is pediatric THC prescribing well documented?

Not in this study. Significant gaps in documentation of indications, dosage, and treatment duration were found, raising patient safety concerns.

Read More on RethinkTHC

Cite This Study

RTHC-04492·https://rethinkthc.com/research/RTHC-04492

APA

de Gier, Charlotte; Scharinger, Christian; Stark, Rosa H; Steurer, Philipp; Klier, Claudia M. (2023). Tetrahydrocannabinol in Pediatrics: Room for Improvement?. Medical cannabis and cannabinoids, 6(1), 125-129. https://doi.org/10.1159/000533607

MLA

de Gier, Charlotte, et al. "Tetrahydrocannabinol in Pediatrics: Room for Improvement?." Medical cannabis and cannabinoids, 2023. https://doi.org/10.1159/000533607

RethinkTHC

RethinkTHC Research Database. "Tetrahydrocannabinol in Pediatrics: Room for Improvement?" RTHC-04492. Retrieved from https://rethinkthc.com/research/de-2023-tetrahydrocannabinol-in-pediatrics-room

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.