Frequent Cannabis Users Are Less Likely to Get Breast and Prostate Cancer Screenings

Heavy cannabis use (20-30 days/month) was associated with 30% lower odds of breast cancer screening and 40% lower odds of prostate cancer screening, but had no effect on cervical or colorectal screening.

Dagnino, Filippo et al.·JCO oncology practice·2025·Moderate EvidenceCross-Sectional
RTHC-06289Cross SectionalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=229,711

What This Study Found

High-frequency cannabis use was associated with lower breast cancer screening adherence (aOR 0.70) and prostate cancer screening at any frequency (1-19 days: aOR 0.76; 20-30 days: aOR 0.60). No significant effect was found for cervical or colorectal cancer screening.

Key Numbers

229,711 patients analyzed. Breast cancer screening: aOR 0.70 (20-30 days use). Prostate screening: aOR 0.60 (20-30 days), 0.76 (1-19 days). No significant effect on cervical or colorectal screening.

How They Did This

Analysis of Behavioral Risk Factor Surveillance System data covering 229,711 patients eligible for cancer screening. Multivariable adjusted models assessed cannabis use frequency and screening adherence.

Why This Research Matters

If frequent cannabis use is associated with skipping cancer screenings, clinicians seeing cannabis-using patients may need to be more proactive about screening recommendations.

The Bigger Picture

This may reflect broader healthcare engagement patterns rather than a direct effect of cannabis. Heavy cannabis users may be less likely to seek preventive care in general.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish causation. Self-reported cannabis use and screening adherence. Cannot distinguish recreational from medical users. Confounders like healthcare access may explain the association.

Questions This Raises

  • ?Is the association driven by cannabis itself or by the demographics of heavy users?
  • ?Would targeted screening reminders for cannabis users close this gap?
  • ?Does medical cannabis use show the same pattern?

Trust & Context

Key Stat:
40% lower prostate cancer screening adherence among daily cannabis users
Evidence Grade:
Large population-based survey with multivariable adjustment; moderate because of sample size despite cross-sectional limitations.
Study Age:
2025 publication using BRFSS survey data
Original Title:
Association of Cannabis Use With Guideline-Recommended Cancer Screenings: Results From a National Health Behaviors Survey.
Published In:
JCO oncology practice, OP2401093 (2025)
Database ID:
RTHC-06289

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does cannabis cause people to skip cancer screenings?

This study found an association, not causation. Heavy cannabis users were less likely to be up-to-date on certain screenings, but this could reflect broader health behaviors rather than a direct effect of cannabis.

Why were only breast and prostate screenings affected?

The researchers speculate this may relate to screening accessibility or the demographics of heavy cannabis users. Cervical and colorectal screenings showed no significant association with cannabis use at any frequency.

Read More on RethinkTHC

Cite This Study

RTHC-06289·https://rethinkthc.com/research/RTHC-06289

APA

Dagnino, Filippo; Pohl, Klara K; Qian, Zhiyu; Zurl, Hanna; Stelzl, Daniel; Korn, Stephan M; Lughezzani, Giovanni; Buffi, Nicolò M; Kibel, Adam S; Trinh, Quoc-Dien; Cole, Alexander P. (2025). Association of Cannabis Use With Guideline-Recommended Cancer Screenings: Results From a National Health Behaviors Survey.. JCO oncology practice, OP2401093. https://doi.org/10.1200/OP-24-01093

MLA

Dagnino, Filippo, et al. "Association of Cannabis Use With Guideline-Recommended Cancer Screenings: Results From a National Health Behaviors Survey.." JCO oncology practice, 2025. https://doi.org/10.1200/OP-24-01093

RethinkTHC

RethinkTHC Research Database. "Association of Cannabis Use With Guideline-Recommended Cance..." RTHC-06289. Retrieved from https://rethinkthc.com/research/dagnino-2025-association-of-cannabis-use

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.