Anxiety disorders drive most of Australia's 300,000 medical cannabis prescriptions for psychiatric conditions
One-third of Australia's roughly 300,000 medical cannabis approvals were for psychiatric conditions, with anxiety disorders accounting for two-thirds of psychiatry-related prescribing, often for conditions lacking strong clinical evidence.
Quick Facts
What This Study Found
Of approximately 300,000 Special Access Scheme B approvals for medical cannabis in Australia (2016-2022), 33.9% were for psychiatric conditions. Anxiety disorders dominated (66.7% of psychiatry-related prescribing), followed by sleep-wake disorders (18.2%), trauma/stressor-related disorders (5.8%), and neurodevelopmental disorders (4.4%). CBD-dominant products comprised 20% of prescribing, particularly for autism spectrum disorder. Dramatic increases in ADHD prescribing were identified.
Key Numbers
~300,000 SAS-B approvals total; 33.9% for psychiatric conditions; 66.7% of psychiatry prescribing for anxiety; 18.2% sleep-wake; 5.8% trauma/stressor; 4.4% neurodevelopmental; 53% oil products; 31.2% flower; 46.2% of patients aged 25-39
How They Did This
Analysis of Therapeutic Goods Administration Special Access Scheme B application data from November 2016 through September 2022. Conditions categorized according to DSM-5-TR criteria. Prescribing trends analyzed via polynomial regression.
Why This Research Matters
Australia has one of the largest legal medical cannabis programs globally. The dominance of psychiatric prescribing for conditions with limited evidence (anxiety, ADHD, depression) highlights a gap between clinical practice and evidence base.
The Bigger Picture
The rapid growth of psychiatric prescribing, particularly for conditions like ADHD where evidence is minimal, raises questions about whether regulatory frameworks are keeping pace with clinical practice.
What This Study Doesn't Tell Us
SAS-B approval data does not capture actual patient outcomes or whether treatment was effective. Cannot determine if patients also used illicit cannabis. Prescribing trends may reflect practitioner marketing rather than evidence-based practice.
Questions This Raises
- ?Are patients receiving cannabis for anxiety disorders experiencing clinical improvement?
- ?Should prescribing for conditions with minimal evidence require additional justification?
Trust & Context
- Key Stat:
- 66.7% of psychiatric cannabis prescribing was for anxiety disorders
- Evidence Grade:
- Comprehensive national prescribing dataset spanning six years, but approval data cannot assess treatment outcomes or appropriateness.
- Study Age:
- Published 2023 using 2016-2022 data
- Original Title:
- Medicinal cannabis for psychiatry-related conditions: an overview of current Australian prescribing.
- Published In:
- Frontiers in pharmacology, 14, 1142680 (2023)
- Authors:
- Cairns, Elizabeth A(2), Benson, Melissa J(5), Bedoya-Pérez, Miguel A(3), Macphail, Sara L, Mohan, Adith, Cohen, Rhys, Sachdev, Perminder S, McGregor, Iain S
- Database ID:
- RTHC-04442
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What psychiatric conditions is medical cannabis prescribed for in Australia?
Anxiety disorders dominate (66.7% of psychiatric prescribing), followed by sleep disorders (18.2%), trauma/stressor disorders (5.8%), and neurodevelopmental disorders (4.4%). ADHD prescribing has increased dramatically.
Is there evidence supporting these prescriptions?
The study notes that much of this prescribing is for conditions where definitive clinical evidence of cannabis efficacy is lacking, and the high prevalence of THC-containing products raises concerns given psychiatric side effects.
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Cite This Study
https://rethinkthc.com/research/RTHC-04442APA
Cairns, Elizabeth A; Benson, Melissa J; Bedoya-Pérez, Miguel A; Macphail, Sara L; Mohan, Adith; Cohen, Rhys; Sachdev, Perminder S; McGregor, Iain S. (2023). Medicinal cannabis for psychiatry-related conditions: an overview of current Australian prescribing.. Frontiers in pharmacology, 14, 1142680. https://doi.org/10.3389/fphar.2023.1142680
MLA
Cairns, Elizabeth A, et al. "Medicinal cannabis for psychiatry-related conditions: an overview of current Australian prescribing.." Frontiers in pharmacology, 2023. https://doi.org/10.3389/fphar.2023.1142680
RethinkTHC
RethinkTHC Research Database. "Medicinal cannabis for psychiatry-related conditions: an ove..." RTHC-04442. Retrieved from https://rethinkthc.com/research/cairns-2023-medicinal-cannabis-for-psychiatryrelated
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.