Thai Chronic Disease Patients Used Cannabis Tea Daily but Few Knew About Drug Interactions

Among 124 Thai chronic disease patients using cannabis post-legalization, most used cannabis tea daily for diabetes or hypertension, but only 35% were aware of potential drug interactions.

Sripaew, Supakorn et al.·Primary health care research & development·2025·Preliminary EvidenceObservational
RTHC-07712ObservationalPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Preliminary Evidence
Sample
N=11

What This Study Found

Patients primarily used cannabis tea daily to manage diabetes or hypertension, viewing it as a complement rather than alternative to conventional medicines. Many believed cannabis could improve their health, while fewer considered it a threat. However, only 34.7% were aware of potential drug interactions with concurrent medications.

Key Numbers

11 qualitative interviews, 124 survey participants. Most male, married, Buddhist. Daily cannabis tea was the primary form. Complementary use predominant. Only 34.7% aware of drug interactions. Patients viewed cannabis as quality-of-life enhancing.

How They Did This

Exploratory-sequential mixed methods. Phase 1: qualitative semi-structured interviews with 11 patients. Phase 2: cross-sectional survey of 124 patients with diabetes and/or hypertension in southern Thailand, post-legalization.

Why This Research Matters

Thailand's cannabis legalization created a unique situation where traditional herbal medicine practices merged with modern chronic disease management. The low awareness of drug interactions poses a real clinical safety concern.

The Bigger Picture

Thailand's experience is globally relevant as more countries legalize cannabis. The integration of cannabis into traditional medicine practices and chronic disease self-management creates both opportunities and risks that other countries may face.

What This Study Doesn't Tell Us

Small sample from one region of Thailand. Self-reported cannabis use and health beliefs. No clinical outcome data. Cross-sectional design. Cultural context may limit generalizability. No verification of what patients were actually consuming.

Questions This Raises

  • ?Does cannabis tea interact with common diabetes and hypertension medications?
  • ?Would pharmacist-led education improve drug interaction awareness?

Trust & Context

Key Stat:
Evidence Grade:
Small mixed-methods study from a single region with no clinical outcomes provides preliminary evidence on an important practical question.
Study Age:
Conducted during the post-legalization period in Thailand.
Original Title:
Cannabis use experience of patients with chronic disease after revisions to the cannabis legalization regulations: a mixed-methods study in primary care settings in the south of Thailand.
Published In:
Primary health care research & development, 26, e89 (2025)
Database ID:
RTHC-07712

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

How are Thai patients using cannabis for chronic disease?

Most drink cannabis tea daily as a complement to their conventional medications for diabetes or hypertension, drawing on traditional Thai medicine practices.

Is it safe to use cannabis with diabetes or blood pressure medications?

Only 35% of patients in this study were aware of potential drug interactions. The study highlights a safety gap that healthcare providers need to address.

Read More on RethinkTHC

Cite This Study

RTHC-07712·https://rethinkthc.com/research/RTHC-07712

APA

Sripaew, Supakorn; Sornsenee, Phoomjai; Vichitkunakorn, Polathep; Assanangkornchai, Sawitri; Fumaneeshoat, Orapan. (2025). Cannabis use experience of patients with chronic disease after revisions to the cannabis legalization regulations: a mixed-methods study in primary care settings in the south of Thailand.. Primary health care research & development, 26, e89. https://doi.org/10.1017/S146342362510056X

MLA

Sripaew, Supakorn, et al. "Cannabis use experience of patients with chronic disease after revisions to the cannabis legalization regulations: a mixed-methods study in primary care settings in the south of Thailand.." Primary health care research & development, 2025. https://doi.org/10.1017/S146342362510056X

RethinkTHC

RethinkTHC Research Database. "Cannabis use experience of patients with chronic disease aft..." RTHC-07712. Retrieved from https://rethinkthc.com/research/sripaew-2025-cannabis-use-experience-of

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.