One in Three U.S. Adults Has Tried CBD; Delta-8 THC Use Reaches 7.7%

A nationally representative survey found 35% of U.S. adults have used CBD, 7.7% have used delta-8 THC, and most cannabinoid users (except delta-8) report medical rather than recreational motivations.

Satybaldiyeva, Nora et al.·Journal of cannabis research·2025·Moderate EvidenceObservational
RTHC-07578ObservationalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
N=1,523

What This Study Found

Lifetime CBD use was 35.2%, delta-8 THC 7.7%, CBN 4.5%, CBG 1.3%, HHC 1.5%. CBD was used primarily for medical reasons (71.9% medical vs. 47.1% recreational), while delta-8 THC was used primarily for recreation (76.1% recreational vs. 50.9% medical). Top medical reasons across cannabinoids were anxiety, pain, and insomnia.

Key Numbers

CBD: 35.2% lifetime use (71.9% medical, 47.1% recreational). Delta-8 THC: 7.7% (50.9% medical, 76.1% recreational). CBN: 4.5%. CBG: 1.3%. HHC: 1.5%. Top CBD medical reasons: anxiety (14.7%), pain (13.1%), joint pain (11.2%). Top delta-8 medical reasons: anxiety (18.6%), pain (15.2%), insomnia (10.7%).

How They Did This

Cross-sectional survey of 1,523 adults using the probability-based Ipsos KnowledgePanel, representative of 97% of U.S. households. Medical reasons were coded using the Medical Dictionary for Regulatory Activities. Multivariable logistic regression assessed demographic and health behavior correlates.

Why This Research Matters

The Farm Bill-enabled cannabinoid market has expanded rapidly but population-level data on who uses which products and why has been scarce. This study provides the first comprehensive nationally representative snapshot of use across five distinct cannabinoids.

The Bigger Picture

The high prevalence of CBD use and the emergence of delta-8 THC as the second most popular cannabinoid product reflect a rapidly evolving consumer landscape operating largely outside traditional drug regulation. The medical motivation data suggests many users are self-treating conditions that might benefit from clinical guidance.

What This Study Doesn't Tell Us

Lifetime use does not indicate current or regular use. Self-reported motivations may not reflect actual pharmacological effects. Users may not accurately know which cannabinoids their products contain. Survey was conducted at a single time point (October-November 2023).

Questions This Raises

  • ?How many of these lifetime users are currently active users
  • ?Whether self-treating for anxiety and pain with cannabinoids substitutes for or complements conventional medical care

Trust & Context

Key Stat:
Evidence Grade:
Probability-based nationally representative sample with validated coding of medical reasons, though cross-sectional design and self-report introduce typical survey limitations.
Study Age:
Published 2025, survey conducted October-November 2023.
Original Title:
Prevalence and reasons for using cannabidiol, delta-8 tetrahydrocannabinol, cannabinol, cannabigerol, and hexahydrocannabinol among US adults.
Published In:
Journal of cannabis research, 7(1), 100 (2025)
Database ID:
RTHC-07578

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

What is delta-8 THC and why is it so popular?

Delta-8 THC is a cannabinoid typically derived from hemp CBD through chemical conversion. It produces psychoactive effects similar to but milder than regular (delta-9) THC. Its popularity surged after the 2018 Farm Bill because it occupies a legal gray area in many states.

Why do people use CBD and delta-8 for different reasons?

CBD does not produce a high, so people tend to seek it for symptom relief (pain, anxiety, sleep). Delta-8 THC does produce psychoactive effects, which explains why more users report recreational motivation, though half also cite medical reasons.

Read More on RethinkTHC

Cite This Study

RTHC-07578·https://rethinkthc.com/research/RTHC-07578

APA

Satybaldiyeva, Nora; Yang, Kevin H; Kepner, Wayne; Ferran, Karen; Leas, Eric C. (2025). Prevalence and reasons for using cannabidiol, delta-8 tetrahydrocannabinol, cannabinol, cannabigerol, and hexahydrocannabinol among US adults.. Journal of cannabis research, 7(1), 100. https://doi.org/10.1186/s42238-025-00359-8

MLA

Satybaldiyeva, Nora, et al. "Prevalence and reasons for using cannabidiol, delta-8 tetrahydrocannabinol, cannabinol, cannabigerol, and hexahydrocannabinol among US adults.." Journal of cannabis research, 2025. https://doi.org/10.1186/s42238-025-00359-8

RethinkTHC

RethinkTHC Research Database. "Prevalence and reasons for using cannabidiol, delta-8 tetrah..." RTHC-07578. Retrieved from https://rethinkthc.com/research/satybaldiyeva-2025-prevalence-and-reasons-for

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.