Nearly 1 in 4 Canadian fibromyalgia patients had tried medical cannabis after legalization

Among 117 fibromyalgia patients in a Canadian rheumatology clinic surveyed after cannabis legalization, 24% had ever used medical cannabis, with 61% of those continuing use and reporting substantial symptom relief (7 out of 10).

Fitzcharles, Mary-Ann et al.·Clinical and experimental rheumatology·2021·Moderate EvidenceCross-Sectional
RTHC-03132Cross SectionalModerate Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

23.9% of FM patients reported ever using medical cannabis, compared to 11.1% of non-FM rheumatology patients. Among FM ever-users, 61% continued use. FM cannabis users tended to be younger (53 vs. 58 years), were more likely unemployed/disabled (39% vs. 17%, p=0.019), used more medications, and reported substantial symptom relief (VAS 7.0/10). Cigarette smoking and recreational cannabis use were more common among ever-users.

Key Numbers

1,000 rheumatology patients; 117 (11.7%) with FM; 23.9% FM ever-users vs. 11.1% non-FM; 61% of FM users continued; FM users younger (53 vs. 58, p=0.072); more unemployed/disabled (39% vs. 17%, p=0.019); self-reported relief 7.0/10

How They Did This

Cross-sectional survey of 1,000 consecutive rheumatology patients during June-August 2019 in Canada. Rheumatologists completed demographic/disease questionnaires; patients completed anonymous questionnaires on cannabis use and health status. Compared FM patients to non-FM patients and FM cannabis users to FM non-users.

Why This Research Matters

Fibromyalgia has limited effective treatments, and cannabis legalization has made it easier for patients to self-medicate. Understanding who uses medical cannabis and their perceived benefits helps guide clinical conversations.

The Bigger Picture

The high self-reported relief score (7/10) and continuation rate (61%) suggest FM patients find meaningful benefit from medical cannabis, though the role of prior smoking and recreational use as facilitators warrants consideration in clinical counseling.

What This Study Doesn't Tell Us

Cross-sectional survey at one rheumatology center. Self-reported cannabis use and symptom relief without objective measures. No control for placebo effect. FM cannabis users used more medications overall, confounding symptom assessment.

Questions This Raises

  • ?Does prior recreational cannabis use bias perceived medical benefit?
  • ?Would FM patients naive to cannabis show the same high satisfaction rates?
  • ?What specific cannabinoid ratios do FM patients find most helpful?

Trust & Context

Key Stat:
7.0 out of 10 self-reported symptom relief among FM cannabis users
Evidence Grade:
Cross-sectional survey in a clinical setting with a reasonable sample size, but self-reported outcomes and no placebo control limit conclusions.
Study Age:
Published in 2021 using June-August 2019 survey data.
Original Title:
Use of medical cannabis by patients with fibromyalgia in Canada after cannabis legalisation: a cross-sectional study.
Published In:
Clinical and experimental rheumatology, 39 Suppl 130(3), 115-119 (2021)
Database ID:
RTHC-03132

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

How common is medical cannabis use among fibromyalgia patients?

In this Canadian clinic surveyed after legalization, nearly 1 in 4 fibromyalgia patients (23.9%) had tried medical cannabis, compared to about 1 in 9 (11.1%) non-FM rheumatology patients. Over 60% of FM users continued treatment.

Did it help?

Users reported substantial relief, averaging 7 out of 10 on a symptom relief scale. However, this was self-reported without a comparison group, so the role of expectations and placebo effect cannot be ruled out.

Read More on RethinkTHC

Cite This Study

RTHC-03132·https://rethinkthc.com/research/RTHC-03132

APA

Fitzcharles, Mary-Ann; Rampakakis, Emmanouil; Sampalis, John S; Shir, Yoram; Cohen, Martin; Starr, Michael; Häuser, Winfried. (2021). Use of medical cannabis by patients with fibromyalgia in Canada after cannabis legalisation: a cross-sectional study.. Clinical and experimental rheumatology, 39 Suppl 130(3), 115-119. https://doi.org/10.55563/clinexprheumatol/qcyet7

MLA

Fitzcharles, Mary-Ann, et al. "Use of medical cannabis by patients with fibromyalgia in Canada after cannabis legalisation: a cross-sectional study.." Clinical and experimental rheumatology, 2021. https://doi.org/10.55563/clinexprheumatol/qcyet7

RethinkTHC

RethinkTHC Research Database. "Use of medical cannabis by patients with fibromyalgia in Can..." RTHC-03132. Retrieved from https://rethinkthc.com/research/fitzcharles-2021-use-of-medical-cannabis

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.