Race- and Gender-Based Discrimination Were Linked to Worse Cannabis Use Outcomes in Young Adults

In a diverse sample of 2,303 young adults, experiencing race- and gender-based discrimination was associated with more cannabis consequences, use disorder symptoms, and solitary use.

Perez, Lilian G et al.·The American journal on addictions·2025·Moderate EvidenceCross-Sectional
RTHC-07350Cross SectionalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=2,303

What This Study Found

Race-based and gender-based discrimination, as well as experiencing multiple types of discrimination, were associated with worse cannabis use outcomes including more consequences, higher use disorder scores, and more solitary use. Interestingly, race-based discrimination was associated with fewer alcohol consequences and lower AUDIT scores. Sexual orientation-based discrimination was not significantly associated with substance use outcomes.

Key Numbers

N=2,303 young adults, mean age 24.7. 47% Latinx/o, 22% Asian, 22% sexual/gender diverse, 56% female. 46% reported up to 4 discrimination types. 27% reported race-based, 26% gender-based, 5% sexual orientation-based discrimination. Race- and gender-based discrimination linked to worse cannabis outcomes. Race-based discrimination linked to fewer alcohol problems.

How They Did This

Cross-sectional analysis of 2,303 young adults (mean age 24.7) predominantly in southern California. Associations between perceived everyday discrimination experiences (race-, gender-, and sexual orientation-based) and self-reported alcohol and cannabis use outcomes were examined.

Why This Research Matters

Discrimination is increasingly recognized as a social determinant of health, but its relationship with cannabis use specifically has been understudied. This study suggests that experiencing discrimination may drive people toward cannabis use as a coping mechanism, particularly through solitary use, which is a marker of more problematic consumption.

The Bigger Picture

The finding that discrimination is linked to worse cannabis outcomes but better alcohol outcomes is intriguing. It suggests that individuals experiencing discrimination may shift their coping substance use toward cannabis rather than alcohol, possibly because cannabis can be used more privately. This has implications for how substance use prevention programs are designed for marginalized populations.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish whether discrimination leads to cannabis use or other causal pathways. Self-reported discrimination and substance use. Southern California sample may not generalize nationally. Cannot control for all potential confounders. Solitary use was self-reported.

Questions This Raises

  • ?Why does discrimination predict worse cannabis but not alcohol outcomes?
  • ?Is solitary cannabis use a mediating mechanism between discrimination and cannabis problems?
  • ?Would discrimination-informed substance use interventions be more effective for marginalized youth?

Trust & Context

Key Stat:
Discrimination linked to worse cannabis outcomes in 2,303 young adults
Evidence Grade:
Moderate evidence from a reasonably large, diverse young adult sample, though limited by cross-sectional design.
Study Age:
2025 study examining discrimination and substance use in a diverse young adult cohort.
Original Title:
Discrimination experiences and problematic alcohol and cannabis use in young adulthood.
Published In:
The American journal on addictions, 34(1), 30-39 (2025)
Database ID:
RTHC-07350

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does experiencing discrimination affect cannabis use?

In this study, young adults who experienced race-based or gender-based discrimination had more cannabis-related consequences, higher cannabis use disorder scores, and more solitary cannabis use. Experiencing multiple types of discrimination was associated with even worse outcomes.

Why might discrimination lead to more cannabis use but not more alcohol use?

The study found race-based discrimination was actually associated with fewer alcohol problems, suggesting people experiencing discrimination may preferentially turn to cannabis rather than alcohol. The researchers speculate this could relate to cannabis being more amenable to private, solitary use as a coping mechanism.

Read More on RethinkTHC

Cite This Study

RTHC-07350·https://rethinkthc.com/research/RTHC-07350

APA

Perez, Lilian G; Troxel, Wendy M; Tucker, Joan S; Dunbar, Michael S; Rodriguez, Anthony; Klein, David J; D'Amico, Elizabeth J. (2025). Discrimination experiences and problematic alcohol and cannabis use in young adulthood.. The American journal on addictions, 34(1), 30-39. https://doi.org/10.1111/ajad.13632

MLA

Perez, Lilian G, et al. "Discrimination experiences and problematic alcohol and cannabis use in young adulthood.." The American journal on addictions, 2025. https://doi.org/10.1111/ajad.13632

RethinkTHC

RethinkTHC Research Database. "Discrimination experiences and problematic alcohol and canna..." RTHC-07350. Retrieved from https://rethinkthc.com/research/perez-2025-discrimination-experiences-and-problematic

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.