Cannabis use shifted from recreational to medical purposes after spinal cord injury

Among 80 Canadians with spinal cord injury, 42.5% used cannabis post-injury, shifting from recreational to pain relief and sleep, with edibles replacing smoking as the preferred method.

Allison, David J et al.·Archives of rehabilitation research and clinical translation·2025·Preliminary EvidenceCross-Sectional
RTHC-05913Cross SectionalPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Preliminary Evidence
Sample
N=80

What This Study Found

Of 80 Canadian adults with spinal cord injury, 42.5% reported cannabis use post-injury and 37.5% were current users, exceeding the general Canadian population rate of 25%. Post-injury, the primary reasons for use shifted from recreation (25%) to pain relief (36.3%) and sleep improvement (30%). Users reported moderate perceived effectiveness. Edibles replaced smoking as the most common consumption method post-injury. Adverse events were generally mild and infrequent, with fatigue the most common (11.3%).

Key Numbers

n=80 (61.2% men; mean age 57.7); 42.5% used cannabis post-injury; 37.5% current users (vs 25% general population); reasons shifted to pain (36.3%) and sleep (30%); fatigue most common side effect (11.3%)

How They Did This

Online survey of Canadian adults with any level or severity of spinal cord injury (N=80). Assessed prevalence, frequency, reasons for use, perceived effectiveness, adverse events, and consumption modality.

Why This Research Matters

Spinal cord injury often produces chronic pain and sleep disruption that are difficult to treat with conventional medications. The shift from recreational to therapeutic use and from smoking to edibles reflects how injury changes cannabis use patterns, information that clinicians need to provide informed guidance.

The Bigger Picture

People with spinal cord injuries are adopting cannabis therapeutically at rates well above the general population, yet clinical evidence to guide their use remains limited. This survey captures the lived experience that clinical trials have not yet addressed.

What This Study Doesn't Tell Us

Small sample (n=80) recruited online, introducing selection bias. Self-reported outcomes without clinical validation. No comparison group or standardized outcome measures. Cannot assess actual efficacy, only perceived effectiveness.

Questions This Raises

  • ?Would controlled trials of cannabis for SCI-related pain and sleep disruption confirm the moderate effectiveness users report?
  • ?What drives the shift from smoking to edibles post-injury?

Trust & Context

Key Stat:
42.5% used cannabis post-injury vs 25% general population
Evidence Grade:
Small online survey provides preliminary descriptive data about cannabis use patterns in SCI but cannot establish efficacy or generalizability.
Study Age:
2025 publication
Original Title:
Understanding Cannabis Use After Spinal Cord Injury: A Canadian Survey Study.
Published In:
Archives of rehabilitation research and clinical translation, 7(4), 100498 (2025)
Database ID:
RTHC-05913

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Why did cannabis use change after spinal cord injury?

Before injury, recreation was the primary reason for use (25%). After injury, pain relief (36.3%) and sleep improvement (30%) became the dominant motivations, reflecting the chronic symptoms associated with SCI.

Were there safety concerns?

Adverse events were generally mild and infrequent, with fatigue (11.3%) being the most common. However, without controlled comparisons, the full safety profile in this population remains uncertain.

Read More on RethinkTHC

Cite This Study

RTHC-05913·https://rethinkthc.com/research/RTHC-05913

APA

Allison, David J; Ebrahimzadeh, Sanam; Agudelo, Alexandria Roa; Lawson, Arden; Kassem, Daad; Loh, Eldon. (2025). Understanding Cannabis Use After Spinal Cord Injury: A Canadian Survey Study.. Archives of rehabilitation research and clinical translation, 7(4), 100498. https://doi.org/10.1016/j.arrct.2025.100498

MLA

Allison, David J, et al. "Understanding Cannabis Use After Spinal Cord Injury: A Canadian Survey Study.." Archives of rehabilitation research and clinical translation, 2025. https://doi.org/10.1016/j.arrct.2025.100498

RethinkTHC

RethinkTHC Research Database. "Understanding Cannabis Use After Spinal Cord Injury: A Canad..." RTHC-05913. Retrieved from https://rethinkthc.com/research/allison-2025-understanding-cannabis-use-after

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.