Regular Marijuana Smoking Was Linked to Worse Self-Rated Health, Especially When Combined with Tobacco

Among US adults who had used marijuana, regular marijuana smoking with tobacco doubled the odds of reporting poor health, and regular marijuana alone still increased odds by 34%, compared to non-regular users without tobacco.

Tsai, James et al.·Preventive medicine reports·2017·Moderate EvidenceCross-Sectional
RTHC-01539Cross SectionalModerate Evidence2017RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=3,210

What This Study Found

Using nationally representative NHANES data (2009-2012) from 3,210 adults who had used marijuana at least once, researchers examined how patterns of marijuana and tobacco co-use related to self-rated health.

Among ever marijuana users, 24.7% were regular marijuana smokers who also currently used tobacco, 21.1% were regular marijuana smokers without tobacco, and 15.2% were non-regular marijuana smokers with tobacco.

Compared to non-regular marijuana users without tobacco (the reference group), the adjusted prevalence ratios for reporting "fair" or "poor" health were: regular marijuana + tobacco: 1.98 (nearly double the odds), non-regular marijuana + tobacco: 1.82, and regular marijuana without tobacco: 1.34.

Tobacco use was the dominant driver of worse self-rated health, but regular marijuana use alone was also significantly associated with suboptimal health status.

Key Numbers

3,210 NHANES respondents. Regular marijuana + tobacco: aPR 1.98 (CI 1.50-2.61). Non-regular marijuana + tobacco: aPR 1.82 (CI 1.40-2.37). Regular marijuana without tobacco: aPR 1.34 (CI 1.05-1.69). Tobacco verified by cotinine ≥3.08 ng/mL.

How They Did This

Cross-sectional analysis of NHANES 2009-2012 data. Tobacco use verified by serum cotinine levels (not self-report). Regular marijuana use defined as at least once monthly for more than one year. Multivariable log-linear regression controlled for demographics and other covariates.

Why This Research Matters

This study separates the effects of marijuana and tobacco, which are commonly used together. The finding that regular marijuana use alone (without tobacco) was still associated with worse self-rated health challenges the narrative that marijuana is entirely benign. However, the effect was much smaller than tobacco's contribution.

The Bigger Picture

The marijuana-tobacco co-use pattern is the norm, not the exception: among regular marijuana users, nearly half also use tobacco. Disentangling the health effects of each substance is critical for public health messaging. This study suggests that while tobacco is the larger health concern, regular marijuana use has its own independent association with worse perceived health.

What This Study Doesn't Tell Us

Cross-sectional design cannot determine causation. Self-rated health is subjective and influenced by many factors. The association between regular marijuana use and poor self-rated health could reflect confounding by other health behaviors, socioeconomic factors, or the conditions that lead people to use marijuana. Regular use was defined as monthly for a year, which encompasses a wide range of consumption patterns.

Questions This Raises

  • ?Is the marijuana-health association due to smoking or cannabis itself?
  • ?Would non-smoking consumption methods show the same pattern?
  • ?Does self-rated health capture actual clinical outcomes or broader psychosocial factors?

Trust & Context

Key Stat:
Regular marijuana + tobacco: 98% higher odds of poor self-rated health vs. non-regular/no-tobacco
Evidence Grade:
Moderate evidence from nationally representative survey data with objective tobacco verification.
Study Age:
Published in 2017, using 2009-2012 NHANES data.
Original Title:
Patterns of marijuana and tobacco use associated with suboptimal self-rated health among US adult ever users of marijuana.
Published In:
Preventive medicine reports, 6, 251-257 (2017)
Database ID:
RTHC-01539

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Is marijuana bad for your health even without tobacco?

This study found that regular marijuana smoking without tobacco was associated with 34% higher odds of poor self-rated health compared to non-regular users without tobacco. While the effect was much smaller than tobacco's, it suggests marijuana use alone is not health-neutral. However, self-rated health is subjective and the study cannot prove marijuana caused the worse ratings.

Which is worse for health, marijuana or tobacco?

In this study, tobacco had a much larger association with poor self-rated health than marijuana. The combination of both was worst (98% higher odds), tobacco alone was next (82% higher), and marijuana alone was smallest (34% higher). This aligns with broader evidence that tobacco remains the greater public health concern.

Read More on RethinkTHC

Cite This Study

RTHC-01539·https://rethinkthc.com/research/RTHC-01539

APA

Tsai, James; Rolle, Italia V; Singh, Tushar; Boulet, Sheree L; McAfee, Timothy A; Grant, Althea M. (2017). Patterns of marijuana and tobacco use associated with suboptimal self-rated health among US adult ever users of marijuana.. Preventive medicine reports, 6, 251-257. https://doi.org/10.1016/j.pmedr.2017.03.014

MLA

Tsai, James, et al. "Patterns of marijuana and tobacco use associated with suboptimal self-rated health among US adult ever users of marijuana.." Preventive medicine reports, 2017. https://doi.org/10.1016/j.pmedr.2017.03.014

RethinkTHC

RethinkTHC Research Database. "Patterns of marijuana and tobacco use associated with subopt..." RTHC-01539. Retrieved from https://rethinkthc.com/research/tsai-2017-patterns-of-marijuana-and

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.