Non-Medical Prescription Opioid Use Was High Among Ontario Students, With Cannabis Use as a Key Predictor

In Ontario, 15.5% of students and 5.9% of adults reported non-medical prescription opioid use, with cannabis use independently associated with opioid misuse in male adults.

Fischer, Benedikt et al.·Drug and alcohol review·2013·Moderate EvidenceCross-Sectional
RTHC-00678Cross SectionalModerate Evidence2013RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=4,023

What This Study Found

Two representative surveys in Ontario examined non-medical prescription opioid use (NMPOU): 4,023 adults and 3,266 secondary school students. NMPOU prevalence was notably high, especially among students (15.5%) compared to adults (5.9%).

Multivariate analyses revealed different predictors by sex and age group. For male students, other drug use was the strongest independent predictor. For female students, rural residence, subjective social status, other drug use, and suicidal ideation were all independently associated. Among male adults, marital status and cannabis use were independent predictors. Among female adults, binge drinking was the key factor.

Key Numbers

Students: 15.5% past-year NMPOU. Adults: 5.9% past-year NMPOU. Independent predictors varied by sex. Cannabis use independently associated with NMPOU in male adults. Suicidal ideation associated in female students.

How They Did This

Two population surveys: the Centre for Addiction and Mental Health Monitor (CM), a random-digit-dialing telephone survey of 4,023 adults (2010-2011 cycles), and the Ontario Student Drug Use and Health Survey (OSDUHS), a school-based questionnaire of 3,266 students in grades 7-12 (2011). Logistic regression identified independent predictors.

Why This Research Matters

The finding that NMPOU was three times higher in students than adults signals that adolescence is a particularly high-risk period for prescription opioid misuse. The association between cannabis use and opioid misuse in adults raises questions about polysubstance use patterns.

The Bigger Picture

This study contributed to the growing evidence that prescription opioid misuse was reaching epidemic levels, particularly among young people. The sex-specific predictor patterns suggest prevention strategies need to be tailored rather than one-size-fits-all.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish causal direction between cannabis use and opioid misuse. Self-reported data may underestimate true prevalence. The telephone-based adult survey may miss certain populations. Ontario-specific findings may not generalize to other regions.

Questions This Raises

  • ?Does cannabis use precede, follow, or occur alongside opioid misuse?
  • ?Would addressing cannabis use reduce opioid misuse risk?
  • ?Why is NMPOU so much higher in students than adults?

Trust & Context

Key Stat:
15.5% of Ontario students reported non-medical prescription opioid use
Evidence Grade:
Two large representative surveys with multivariate analysis; moderate evidence for prevalence and predictors.
Study Age:
Published in 2013, during the early recognition of the opioid epidemic. The opioid crisis has since intensified dramatically.
Original Title:
Prevalence and key covariates of non-medical prescription opioid use among the general secondary student and adult populations in Ontario, Canada.
Published In:
Drug and alcohol review, 32(3), 276-87 (2013)
Database ID:
RTHC-00678

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does cannabis use lead to opioid misuse?

This study found cannabis use was independently associated with prescription opioid misuse in male adults, but the cross-sectional design cannot determine which came first. People who use one substance are generally more likely to use others, and this association could reflect shared risk factors rather than a direct causal pathway.

Why is prescription opioid misuse higher in students than adults?

At 15.5% versus 5.9%, student NMPOU was nearly three times the adult rate. Adolescents may have easier access through household medicine cabinets, less awareness of addiction risk, more peer influence, and developing impulse control. This age disparity highlights the need for school-based prevention.

Read More on RethinkTHC

Cite This Study

RTHC-00678·https://rethinkthc.com/research/RTHC-00678

APA

Fischer, Benedikt; Ialomiteanu, Anca; Boak, Angela; Adlaf, Edward; Rehm, Jürgen; Mann, Robert E. (2013). Prevalence and key covariates of non-medical prescription opioid use among the general secondary student and adult populations in Ontario, Canada.. Drug and alcohol review, 32(3), 276-87. https://doi.org/10.1111/dar.12025

MLA

Fischer, Benedikt, et al. "Prevalence and key covariates of non-medical prescription opioid use among the general secondary student and adult populations in Ontario, Canada.." Drug and alcohol review, 2013. https://doi.org/10.1111/dar.12025

RethinkTHC

RethinkTHC Research Database. "Prevalence and key covariates of non-medical prescription op..." RTHC-00678. Retrieved from https://rethinkthc.com/research/fischer-2013-prevalence-and-key-covariates

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.