Veterans' Daily Cannabis Use Linked to Same-Day Stress Relief and Better Sleep, But Alcohol Use Worsened Next Day

In a 3-month daily diary study of 74 veterans, cannabis use was associated with lower stress and better sleep that same day, while poor sleep predicted more stress and alcohol use the following day.

Davis, Jordan P et al.·Drug and alcohol dependence·2025·Moderate EvidenceLongitudinal Cohort
RTHC-06304Longitudinal CohortModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Longitudinal Cohort
Evidence
Moderate Evidence
Sample
N=74

What This Study Found

Within-day: higher cannabis use was associated with lower stress and better sleep quality that same night. Day-to-day: worse sleep predicted higher next-day stress, which predicted greater alcohol use. Stress mediated the relationship between poor sleep and increased alcohol consumption. No day-to-day lagged effects were found for cannabis.

Key Numbers

74 veterans, 3-month diary. Cannabis: same-day association with lower stress and better sleep, no next-day lagged effects. Alcohol: poor sleep predicted next-day stress predicted more alcohol use. Stress mediated sleep-to-alcohol relationship.

How They Did This

74 veterans with elevated PTSD symptoms and problematic cannabis use completed 3 months of daily diaries via mobile app. Dynamic structural equation modeling examined within-day and lagged associations between sleep, stress, cannabis, and alcohol.

Why This Research Matters

This companion study to RTHC-06303 reveals that cannabis and alcohol play different roles in the stress-sleep cycle. Cannabis appears to provide same-day relief without next-day consequences, while alcohol use follows a harmful next-day stress pattern.

The Bigger Picture

These contrasting patterns for cannabis and alcohol have clinical implications. If cannabis provides same-day relief without exacerbating next-day symptoms, while alcohol worsens the cycle, substitution of cannabis for alcohol could theoretically reduce harm.

What This Study Doesn't Tell Us

Secondary analysis of an existing dataset. Sample selected for problematic cannabis use, creating selection bias. Cannot establish causation from observational data. Self-reported measures.

Questions This Raises

  • ?Would reducing alcohol use in veterans who use both substances improve their PTSD and sleep outcomes?
  • ?Is the absence of next-day cannabis effects truly benign, or does chronic use have cumulative effects not captured in daily data?

Trust & Context

Key Stat:
Cannabis: same-day stress relief with no next-day hangover effect. Alcohol: poor sleep drives next-day stress and more drinking.
Evidence Grade:
Intensive longitudinal design with DSEM modeling; moderate despite secondary analysis, because within-person design controls for individual differences.
Study Age:
2025 publication using 3-month daily diary data
Original Title:
Daily associations between sleep quality, stress, and cannabis or alcohol use among veterans.
Published In:
Drug and alcohol dependence, 271, 112661 (2025)
Database ID:
RTHC-06304

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Follows a group of people over time to track how outcomes develop.

What do these levels mean? →

Frequently Asked Questions

Is cannabis better than alcohol for veterans with PTSD?

This study found that cannabis was associated with same-day stress relief without worsening next-day symptoms, while alcohol use was part of a harmful cycle of poor sleep, stress, and more drinking. However, this observational data cannot make definitive treatment recommendations.

Why was there no next-day effect for cannabis?

The researchers found that cannabis effects appeared to be contained within the same day. Unlike alcohol, which was linked to a next-day worsening cycle, cannabis use one day did not predict stress, PTSD symptoms, or sleep quality the following day.

Read More on RethinkTHC

Cite This Study

RTHC-06304·https://rethinkthc.com/research/RTHC-06304

APA

Davis, Jordan P; Saba, Shaddy K; Leightley, Daniel; Pedersen, Eric R; Prindle, John; Senator, Ben; Dilkina, Bistra; Dworkin, Emily; Howe, Esther; Cantor, Jonathan; Sedano, Angeles. (2025). Daily associations between sleep quality, stress, and cannabis or alcohol use among veterans.. Drug and alcohol dependence, 271, 112661. https://doi.org/10.1016/j.drugalcdep.2025.112661

MLA

Davis, Jordan P, et al. "Daily associations between sleep quality, stress, and cannabis or alcohol use among veterans.." Drug and alcohol dependence, 2025. https://doi.org/10.1016/j.drugalcdep.2025.112661

RethinkTHC

RethinkTHC Research Database. "Daily associations between sleep quality, stress, and cannab..." RTHC-06304. Retrieved from https://rethinkthc.com/research/davis-2025-daily-associations-between-sleep

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.