Older adults with cannabis use disorder endorsed fewer diagnostic symptoms, potentially masking problem severity

Adults 65+ with cannabis use disorder were significantly less likely to endorse hazardous use and withdrawal criteria compared to younger adults, suggesting current diagnostic tools may underdetect CUD in older populations.

Choi, Namkee G et al.·International journal of environmental research and public health·2025·Moderate EvidenceCross-Sectional
RTHC-06217Cross SectionalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=12,264

What This Study Found

For CUD, adults 65+ had dramatically lower odds of endorsing hazardous use (OR 0.04) and withdrawal (OR 0.39 and 0.16); for AUD, 7 of 11 criteria were endorsed less often by older adults.

Key Numbers

CUD: hazardous use OR 0.04 (95% CI 0.01-0.17); withdrawal A OR 0.39 (0.20-0.73); withdrawal B OR 0.16 (0.05-0.48); AUD: 7 of 11 criteria endorsed less often by 65+.

How They Did This

Cross-sectional analysis of 2021-2023 NSDUH (N=12,264 for CUD, N=17,494 for AUD); multivariable logistic regression for each DSM-5 criterion with age group as independent variable.

Why This Research Matters

If older adults systematically underreport key CUD criteria, they may be underdiagnosed, undermining treatment access.

The Bigger Picture

As cannabis use grows among older adults, diagnostic tools developed on younger populations may need age-specific adaptations.

What This Study Doesn't Tell Us

Self-reported endorsement may reflect true differences or bias; NSDUH may underrepresent severe disorders in elderly; cross-sectional design.

Questions This Raises

  • ?Are older adults truly experiencing fewer symptoms or interpreting them differently?
  • ?Should age-adapted CUD criteria be developed?
  • ?Does retirement mask occupational impairment?

Trust & Context

Key Stat:
Older adults had 96% lower odds of endorsing hazardous cannabis use (OR 0.04)
Evidence Grade:
Large nationally representative sample with criterion-by-criterion analysis, but cannot distinguish true symptom differences from reporting differences.
Study Age:
Published 2025, data 2021-2023
Original Title:
DSM-5 Criteria for Alcohol and Cannabis Use Disorders: Are Older Adults Less Likely to Endorse Certain Criteria?
Published In:
International journal of environmental research and public health, 22(6) (2025)
Database ID:
RTHC-06217

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Do older adults show cannabis use disorder differently?

Yes. Adults 65+ were far less likely to report hazardous use and withdrawal symptoms, the two criteria with the largest age gaps.

Why might this matter?

If older adults experience or report fewer DSM-5 criteria, their CUD may be underdiagnosed or classified as less severe than it actually is.

Read More on RethinkTHC

Cite This Study

RTHC-06217·https://rethinkthc.com/research/RTHC-06217

APA

Choi, Namkee G; Morris, Jeffrey A; Marti, C Nathan. (2025). DSM-5 Criteria for Alcohol and Cannabis Use Disorders: Are Older Adults Less Likely to Endorse Certain Criteria?. International journal of environmental research and public health, 22(6). https://doi.org/10.3390/ijerph22060843

MLA

Choi, Namkee G, et al. "DSM-5 Criteria for Alcohol and Cannabis Use Disorders: Are Older Adults Less Likely to Endorse Certain Criteria?." International journal of environmental research and public health, 2025. https://doi.org/10.3390/ijerph22060843

RethinkTHC

RethinkTHC Research Database. "DSM-5 Criteria for Alcohol and Cannabis Use Disorders: Are O..." RTHC-06217. Retrieved from https://rethinkthc.com/research/choi-2025-dsm5-criteria-for-alcohol

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.