Cannabis Co-Use Makes It Harder to Quit Smoking, But Many Quitline Callers Want Help With Both

Over a quarter of California tobacco quitline callers also used cannabis, and they quit smoking at lower rates (23.2% vs 28.9%), though 43% expressed intent to quit cannabis too.

Zhu, Shu-Hong et al.·American journal of preventive medicine·2024·Moderate EvidenceRetrospective Cohort
RTHC-05852Retrospective CohortModerate Evidence2024RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Retrospective Cohort
Evidence
Moderate Evidence
Sample
N=45,151

What This Study Found

Cannabis co-use was reported by 27.2% of quitline callers. Co-users were more likely to be male, younger, and have mental health conditions. After controlling for demographics and cessation services, co-users were significantly less likely to quit smoking at 7 months (23.2% vs 28.9%, p < .001). Among co-users, 42.9% intended to quit cannabis within 30 days.

Key Numbers

45,151 total callers. 27.2% co-used cannabis. 7-month quit rates: co-users 23.2% vs non-co-users 28.9% (p < .001). Similar rates of receiving counseling and FDA-approved cessation aids between groups. 42.9% of co-users intended to quit cannabis within 30 days. 3,545 evaluated at 7 months.

How They Did This

Analysis of Kick It California (state tobacco quitline) caller data from January 2020 through December 2023 (N=45,151). A subgroup (n=3,545) was randomly sampled for 7-month evaluation. Cessation rates compared between co-users and non-co-users, controlling for demographics and cessation service utilization.

Why This Research Matters

Tobacco quitlines are one of the most widely used cessation resources. Learning that over a quarter of their callers also use cannabis -- and that co-use lowers quit rates -- identifies both a problem and an opportunity. The 43% expressing cannabis quit intentions suggests these callers are open to dual intervention.

The Bigger Picture

As cannabis use increases nationally while cigarette smoking declines, the co-use population represents a growing challenge for tobacco cessation. Quitlines that ignore cannabis co-use may be undermining their own effectiveness for over a quarter of their callers.

What This Study Doesn't Tell Us

Observational data from a single state quitline. Self-reported outcomes may overestimate quit rates. The association between co-use and lower quit rates could reflect shared underlying risk factors rather than a direct effect of cannabis on smoking cessation.

Questions This Raises

  • ?Would adding cannabis cessation support to tobacco quitlines improve smoking quit rates?
  • ?Does co-use interfere with smoking cessation through pharmacological mechanisms or behavioral patterns?

Trust & Context

Key Stat:
27.2% of tobacco quitline callers also used cannabis
Evidence Grade:
Moderate: very large quitline dataset with 7-month follow-up and controlled analyses, but single state and self-reported outcomes.
Study Age:
2024 study using 2020-2023 data.
Original Title:
Tobacco Quitline Callers Who Use Cannabis and Their Likelihood of Quitting Cigarette Smoking.
Published In:
American journal of preventive medicine, 67(2), 241-248 (2024)
Database ID:
RTHC-05852

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Looks back at existing records to find patterns.

What do these levels mean? →

Frequently Asked Questions

Does cannabis make it harder to quit smoking?

In this study, cannabis co-users had significantly lower smoking quit rates even after controlling for demographics and use of cessation services. Whether this reflects pharmacological interactions, behavioral patterns, or shared risk factors is not yet clear.

Could quitlines help with cannabis too?

The finding that 43% of co-users intended to quit cannabis within 30 days suggests strong receptivity. Quitlines are already trusted by these callers, making them a logical platform for expanding to dual substance cessation support.

Read More on RethinkTHC

Cite This Study

RTHC-05852·https://rethinkthc.com/research/RTHC-05852

APA

Zhu, Shu-Hong; Tedeschi, Gary J; Li, Shuwen; Wang, Jijiang; Aughinbaugh, Emily; Pratt, Andrea S; Zhuang, Yue-Lin. (2024). Tobacco Quitline Callers Who Use Cannabis and Their Likelihood of Quitting Cigarette Smoking.. American journal of preventive medicine, 67(2), 241-248. https://doi.org/10.1016/j.amepre.2024.03.007

MLA

Zhu, Shu-Hong, et al. "Tobacco Quitline Callers Who Use Cannabis and Their Likelihood of Quitting Cigarette Smoking.." American journal of preventive medicine, 2024. https://doi.org/10.1016/j.amepre.2024.03.007

RethinkTHC

RethinkTHC Research Database. "Tobacco Quitline Callers Who Use Cannabis and Their Likeliho..." RTHC-05852. Retrieved from https://rethinkthc.com/research/zhu-2024-tobacco-quitline-callers-who

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.