The DSM-5 Craving Criterion Was Validated for Cannabis and Five Other Substances, With Moderate Craving More Predictive Than Severe

In a study of 588 adults, the DSM-5 craving criterion was valid across cannabis, alcohol, tobacco, cocaine, heroin, and opioids, with moderate craving ("felt a very strong desire or urge") more strongly associated with clinical validators than severe craving ("could not think of anything else").

Shmulewitz, D et al.·Psychological medicine·2023·Strong Evidencevalidation-study
RTHC-04934Validation StudyStrong Evidence2023RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
validation-study
Evidence
Strong Evidence
Sample
N=588

What This Study Found

Across all six substances, craving was associated with most baseline validators. Moderate craving was more strongly associated with validators than severe craving and improved predictive validity for daily substance use. Including craving improved the validity and clinical relevance of DSM-5 SUD diagnoses across all substances.

Key Numbers

N=588 adults. 6 substances assessed. 90-day daily electronic monitoring. Moderate craving more predictive than severe. Craving improved SUD diagnostic validity across all substances.

How They Did This

Validation study of 588 adults who engaged in binge drinking or illicit drug use and endorsed at least one DSM-5 SUD criterion. Assessed craving across 6 substances. Logistic regression estimated associations with validators. Electronic daily assessment tracked use for 90 days.

Why This Research Matters

The DSM-5 added craving as a new diagnostic criterion for substance use disorders but it had not been systematically validated across substances. This study confirms it belongs in the diagnosis and works consistently across different drugs including cannabis.

The Bigger Picture

For cannabis specifically, validating the craving criterion matters because some have questioned whether cannabis produces "real" cravings comparable to harder drugs. This study shows the craving criterion works just as well for cannabis as for heroin or cocaine.

What This Study Doesn't Tell Us

Sample required at least one SUD criterion, so results may not generalize to casual users. Self-reported craving may be interpreted differently across individuals. 90-day follow-up captures a limited window. Cannot determine whether craving causes continued use or vice versa.

Questions This Raises

  • ?Why is moderate craving more predictive than severe craving?
  • ?Could craving assessments be used as a treatment monitoring tool for cannabis use disorder?

Trust & Context

Key Stat:
The DSM-5 craving criterion is valid for cannabis just as for heroin and cocaine
Evidence Grade:
Well-designed validation study with 90-day daily monitoring across 6 substances in a clinical sample.
Study Age:
Published in 2023.
Original Title:
Validity of the DSM-5 craving criterion for alcohol, tobacco, cannabis, cocaine, heroin, and non-prescription use of prescription painkillers (opioids).
Published In:
Psychological medicine, 53(5), 1955-1969 (2023)
Database ID:
RTHC-04934

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

Is cannabis craving a real clinical phenomenon?

Yes. This study validated the DSM-5 craving criterion for cannabis just as it did for alcohol, tobacco, cocaine, heroin, and opioids. Cannabis craving was consistently associated with clinical indicators of substance use disorder.

What level of craving is most concerning?

Moderate craving ("a very strong desire or urge to use") was actually more predictive of clinical problems than severe craving ("could not think of anything else"), possibly because severe craving is less commonly endorsed.

Read More on RethinkTHC

Cite This Study

RTHC-04934·https://rethinkthc.com/research/RTHC-04934

APA

Shmulewitz, D; Stohl, M; Greenstein, E; Roncone, S; Walsh, C; Aharonovich, E; Wall, M M; Hasin, D S. (2023). Validity of the DSM-5 craving criterion for alcohol, tobacco, cannabis, cocaine, heroin, and non-prescription use of prescription painkillers (opioids).. Psychological medicine, 53(5), 1955-1969. https://doi.org/10.1017/S0033291721003652

MLA

Shmulewitz, D, et al. "Validity of the DSM-5 craving criterion for alcohol, tobacco, cannabis, cocaine, heroin, and non-prescription use of prescription painkillers (opioids).." Psychological medicine, 2023. https://doi.org/10.1017/S0033291721003652

RethinkTHC

RethinkTHC Research Database. "Validity of the DSM-5 craving criterion for alcohol, tobacco..." RTHC-04934. Retrieved from https://rethinkthc.com/research/shmulewitz-2023-validity-of-the-dsm5

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.