Childhood Trauma Predicts Cannabis Use in New Mothers, But Resilience May Help (Up to a Point)
Among mothers with high resilience scores, each additional adverse childhood experience increased odds of cannabis use by 38%, while mothers with low resilience showed consistently high cannabis use regardless of trauma history.
Quick Facts
What This Study Found
In 126 predominantly low-income mothers followed through three years postpartum, the relationship between adverse childhood experiences (ACEs) and cannabis use depended on resilience level. Among high-resilience mothers, each additional ACE increased cannabis use odds by 38% (adjusted OR=1.38). Predicted probability of cannabis use in this group rose from 8.5% at 0 ACEs to 62.9% at 10 ACEs. Among low-resilience mothers, cannabis use probability remained around 36% regardless of ACE exposure.
Key Numbers
126 mothers. High resilience group: cannabis use probability 8.5% at 0 ACEs, 62.9% at 10 ACEs (OR=1.38 per ACE). Low resilience group: ~36% cannabis use probability regardless of ACE score (OR=1.02, not significant).
How They Did This
Longitudinal study of 126 predominantly low-income, diverse mothers in the South Central US. Multiple logistic regression evaluated ACEs and cannabis use through 3 years postpartum, stratified by resilience (median split). Adjusted for sociodemographics, postnatal depression, and prenatal substance use.
Why This Research Matters
Cannabis use in early motherhood is increasing, and understanding what drives it can inform more targeted support. The finding that resilience appears protective at low-to-moderate trauma exposure but loses its protective effect at high ACE levels suggests that different intervention strategies may be needed depending on a mother's trauma history.
The Bigger Picture
This study adds nuance to the ACEs-substance use connection. Rather than a simple 'more trauma equals more use' model, the relationship depends on protective factors. The finding that resilience's protective effect has limits at high trauma levels has implications for how support programs are designed for mothers with extensive childhood adversity.
What This Study Doesn't Tell Us
Small sample size (n=126). Predominantly low-income population in one US region. Cannabis use was self-reported. Resilience measured at a single point. Cannot determine whether cannabis use represents problematic use or intentional self-management. Observational design limits causal claims.
Questions This Raises
- ?Why does resilience appear to lose its protective effect at high ACE levels?
- ?Are mothers using cannabis to cope with trauma symptoms, and if so, does it help or hinder recovery?
- ?Would trauma-focused interventions reduce cannabis use in high-ACE mothers?
Trust & Context
- Key Stat:
- Cannabis use probability: 8.5% at 0 ACEs to 62.9% at 10 ACEs (high resilience group)
- Evidence Grade:
- Moderate: longitudinal design with adjusted models, but small sample size and single-region population.
- Study Age:
- Published in 2025.
- Original Title:
- Adverse childhood experiences, resilience, and cannabis use in early motherhood.
- Published In:
- Frontiers in psychiatry, 16, 1621161 (2025)
- Authors:
- Roland, Alysa, Charron, Elizabeth, Shreffler, Karina M
- Database ID:
- RTHC-07517
Evidence Hierarchy
Follows a group of people over time to track how outcomes develop.
What do these levels mean? →Frequently Asked Questions
Does childhood trauma increase cannabis use in mothers?
Among high-resilience mothers, yes: each additional adverse childhood experience increased odds of cannabis use by 38% through three years postpartum. Among low-resilience mothers, cannabis use was elevated (~36%) regardless of trauma level.
Can resilience protect against trauma-related cannabis use?
This study found resilience was protective at low-to-moderate levels of childhood adversity. However, at high levels of trauma (approaching 10 ACEs), even high resilience did not prevent elevated cannabis use.
Read More on RethinkTHC
Cite This Study
https://rethinkthc.com/research/RTHC-07517APA
Roland, Alysa; Charron, Elizabeth; Shreffler, Karina M. (2025). Adverse childhood experiences, resilience, and cannabis use in early motherhood.. Frontiers in psychiatry, 16, 1621161. https://doi.org/10.3389/fpsyt.2025.1621161
MLA
Roland, Alysa, et al. "Adverse childhood experiences, resilience, and cannabis use in early motherhood.." Frontiers in psychiatry, 2025. https://doi.org/10.3389/fpsyt.2025.1621161
RethinkTHC
RethinkTHC Research Database. "Adverse childhood experiences, resilience, and cannabis use ..." RTHC-07517. Retrieved from https://rethinkthc.com/research/roland-2025-adverse-childhood-experiences-resilience
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.