Childhood Trauma Predicts Cannabis Use in New Mothers, But Resilience May Help (Up to a Point)

Among mothers with high resilience scores, each additional adverse childhood experience increased odds of cannabis use by 38%, while mothers with low resilience showed consistently high cannabis use regardless of trauma history.

Roland, Alysa et al.·Frontiers in psychiatry·2025·Moderate EvidenceLongitudinal Cohort
RTHC-07517Longitudinal CohortModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Longitudinal Cohort
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

In 126 predominantly low-income mothers followed through three years postpartum, the relationship between adverse childhood experiences (ACEs) and cannabis use depended on resilience level. Among high-resilience mothers, each additional ACE increased cannabis use odds by 38% (adjusted OR=1.38). Predicted probability of cannabis use in this group rose from 8.5% at 0 ACEs to 62.9% at 10 ACEs. Among low-resilience mothers, cannabis use probability remained around 36% regardless of ACE exposure.

Key Numbers

126 mothers. High resilience group: cannabis use probability 8.5% at 0 ACEs, 62.9% at 10 ACEs (OR=1.38 per ACE). Low resilience group: ~36% cannabis use probability regardless of ACE score (OR=1.02, not significant).

How They Did This

Longitudinal study of 126 predominantly low-income, diverse mothers in the South Central US. Multiple logistic regression evaluated ACEs and cannabis use through 3 years postpartum, stratified by resilience (median split). Adjusted for sociodemographics, postnatal depression, and prenatal substance use.

Why This Research Matters

Cannabis use in early motherhood is increasing, and understanding what drives it can inform more targeted support. The finding that resilience appears protective at low-to-moderate trauma exposure but loses its protective effect at high ACE levels suggests that different intervention strategies may be needed depending on a mother's trauma history.

The Bigger Picture

This study adds nuance to the ACEs-substance use connection. Rather than a simple 'more trauma equals more use' model, the relationship depends on protective factors. The finding that resilience's protective effect has limits at high trauma levels has implications for how support programs are designed for mothers with extensive childhood adversity.

What This Study Doesn't Tell Us

Small sample size (n=126). Predominantly low-income population in one US region. Cannabis use was self-reported. Resilience measured at a single point. Cannot determine whether cannabis use represents problematic use or intentional self-management. Observational design limits causal claims.

Questions This Raises

  • ?Why does resilience appear to lose its protective effect at high ACE levels?
  • ?Are mothers using cannabis to cope with trauma symptoms, and if so, does it help or hinder recovery?
  • ?Would trauma-focused interventions reduce cannabis use in high-ACE mothers?

Trust & Context

Key Stat:
Cannabis use probability: 8.5% at 0 ACEs to 62.9% at 10 ACEs (high resilience group)
Evidence Grade:
Moderate: longitudinal design with adjusted models, but small sample size and single-region population.
Study Age:
Published in 2025.
Original Title:
Adverse childhood experiences, resilience, and cannabis use in early motherhood.
Published In:
Frontiers in psychiatry, 16, 1621161 (2025)
Database ID:
RTHC-07517

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Follows a group of people over time to track how outcomes develop.

What do these levels mean? →

Frequently Asked Questions

Does childhood trauma increase cannabis use in mothers?

Among high-resilience mothers, yes: each additional adverse childhood experience increased odds of cannabis use by 38% through three years postpartum. Among low-resilience mothers, cannabis use was elevated (~36%) regardless of trauma level.

Can resilience protect against trauma-related cannabis use?

This study found resilience was protective at low-to-moderate levels of childhood adversity. However, at high levels of trauma (approaching 10 ACEs), even high resilience did not prevent elevated cannabis use.

Read More on RethinkTHC

Cite This Study

RTHC-07517·https://rethinkthc.com/research/RTHC-07517

APA

Roland, Alysa; Charron, Elizabeth; Shreffler, Karina M. (2025). Adverse childhood experiences, resilience, and cannabis use in early motherhood.. Frontiers in psychiatry, 16, 1621161. https://doi.org/10.3389/fpsyt.2025.1621161

MLA

Roland, Alysa, et al. "Adverse childhood experiences, resilience, and cannabis use in early motherhood.." Frontiers in psychiatry, 2025. https://doi.org/10.3389/fpsyt.2025.1621161

RethinkTHC

RethinkTHC Research Database. "Adverse childhood experiences, resilience, and cannabis use ..." RTHC-07517. Retrieved from https://rethinkthc.com/research/roland-2025-adverse-childhood-experiences-resilience

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.