Cannabis use and cannabis use disorder strongly linked to mental health conditions in pregnant and postpartum women

In a nationally representative US sample, pregnant and postpartum women with mood, anxiety, PTSD, or personality disorders had 2 to 12 times higher odds of cannabis use disorder compared to those without these conditions.

Brown, Qiana L et al.·Drug and alcohol dependence·2023·Strong EvidenceCross-Sectional
RTHC-04436Cross SectionalStrong Evidence2023RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Strong Evidence
Sample
N=1,316

What This Study Found

Among 1,316 pregnant and postpartum women, past-year cannabis use prevalence was 9.8% and cannabis use disorder (CUD) was 3.2%. Women with any past-year mood, anxiety, or PTSD disorder had 2.1 to 3.9 times higher odds of cannabis use, and 2.6 to 10.4 times higher odds of CUD. Specific disorder associations with CUD ranged from 2.4 to 11.6 times higher odds.

Key Numbers

1,316 women (414 pregnant, 902 postpartum); 9.8% past-year cannabis use; 3.2% CUD; cannabis use aORs: 2.10-3.87 for any mood/anxiety/PTSD; CUD aORs: 2.55-10.44; specific disorder CUD aORs: 2.36-11.60

How They Did This

Analysis of the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III). Weighted logistic regression models estimated associations between past-year cannabis use, DSM-5 CUD, and DSM-5 mental health disorders among 414 pregnant and 902 postpartum women aged 18-44.

Why This Research Matters

The pregnancy and postpartum period is already a time of heightened mental health vulnerability. The strong association between mental health disorders and cannabis use/CUD in this population highlights the need for integrated screening and treatment.

The Bigger Picture

As prenatal and postpartum cannabis use increases, the strong comorbidity with mental health disorders suggests that addressing one without the other is likely insufficient.

What This Study Doesn't Tell Us

Cross-sectional data cannot determine whether mental health disorders drive cannabis use or vice versa. Data from 2012-2013 may not reflect current patterns given rapid cannabis legalization. Self-reported cannabis use and psychiatric diagnoses.

Questions This Raises

  • ?Does treating the underlying mental health condition reduce cannabis use during pregnancy?
  • ?How have these associations changed since further cannabis legalization post-2013?

Trust & Context

Key Stat:
Up to 11.6x higher odds of cannabis use disorder with specific mental health diagnoses
Evidence Grade:
Nationally representative survey with DSM-5 diagnostic criteria and weighted analyses, though cross-sectional design limits causal inference.
Study Age:
Published 2023 using 2012-2013 data
Original Title:
Cannabis use, cannabis use disorder and mental health disorders among pregnant and postpartum women in the US: A nationally representative study.
Published In:
Drug and alcohol dependence, 248, 109940 (2023)
Database ID:
RTHC-04436

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Is cannabis use disorder more common in pregnant women with mental health conditions?

Yes. In this national survey, pregnant and postpartum women with mood, anxiety, PTSD, or personality disorders had 2.6 to 10.4 times higher odds of meeting criteria for cannabis use disorder.

How common is cannabis use during pregnancy and postpartum?

In this nationally representative sample, 9.8% of pregnant and postpartum women reported past-year cannabis use, and 3.2% met criteria for cannabis use disorder.

Read More on RethinkTHC

Cite This Study

RTHC-04436·https://rethinkthc.com/research/RTHC-04436

APA

Brown, Qiana L; Shmulewitz, Dvora; Sarvet, Aaron L; Young-Wolff, Kelly C; Howard, Tyriesa; Hasin, Deborah S. (2023). Cannabis use, cannabis use disorder and mental health disorders among pregnant and postpartum women in the US: A nationally representative study.. Drug and alcohol dependence, 248, 109940. https://doi.org/10.1016/j.drugalcdep.2023.109940

MLA

Brown, Qiana L, et al. "Cannabis use, cannabis use disorder and mental health disorders among pregnant and postpartum women in the US: A nationally representative study.." Drug and alcohol dependence, 2023. https://doi.org/10.1016/j.drugalcdep.2023.109940

RethinkTHC

RethinkTHC Research Database. "Cannabis use, cannabis use disorder and mental health disord..." RTHC-04436. Retrieved from https://rethinkthc.com/research/brown-2023-cannabis-use-cannabis-use

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.