Suicidal Thoughts in Young French Adults: Depression Was the Biggest Factor, Cannabis Was Not Independent

Among 4,075 young French adults, depression was the strongest predictor of suicidal ideation (OR ~8), while cannabis use in the previous month was not an independent predictor after adjusting for other factors.

Legleye, S et al.·Journal of affective disorders·2010·Moderate EvidenceCross-Sectional
RTHC-00426Cross SectionalModerate Evidence2010RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=4,075

What This Study Found

Researchers surveyed 4,075 French adults aged 18-30 about suicidal ideation, substance use, and psychosocial factors.

Suicidal ideation in the previous year affected 5.7% of men and 4.9% of women.

Depression was the strongest predictor for both sexes (adjusted OR approximately 8). Among men, other significant predictors included homosexual intercourse (OR 3.37), absence of sexual activity (OR 2.83), living alone, daily tobacco smoking, unemployment, and parental relationship quality.

Among women, forced sexual intercourse (OR 5.37) and illicit drug use other than cannabis (OR 4.01) were significant predictors.

Notably, cannabis use in the previous month was not independently associated with suicidal ideation in the adjusted models for either sex. Other illicit drugs (not cannabis) were significant for women only.

Key Numbers

4,075 adults, ages 18-30. Suicidal ideation: 5.7% men, 4.9% women. Depression OR: ~8 (both sexes). Cannabis: not significant in adjusted models. Non-cannabis illicit drugs: OR 4.01 for women.

How They Did This

Cross-sectional analysis of 4,075 French adults aged 18-30 from a random national telephone survey in 2005. Depression assessed with CIDI-SF. Alcohol abuse assessed with AUDIT-C. Logistic regression with comprehensive adjustment for sociodemographic, health, and behavioral factors.

Why This Research Matters

This large population-based study found that cannabis was not independently associated with suicidal ideation after accounting for depression and other psychosocial factors, consistent with the Swedish longitudinal study (RTHC-00381) finding that confounding explains the cannabis-suicide association.

The Bigger Picture

Multiple studies now suggest that the association between cannabis and suicidality is largely explained by confounding factors, particularly depression and psychosocial adversity. Cannabis use may be a marker for these underlying risk factors rather than an independent cause.

What This Study Doesn't Tell Us

Cross-sectional design. Self-reported data via telephone survey. Cannabis use measured only in the previous month. French cultural context may limit generalizability. Telephone survey may miss marginalized populations.

Questions This Raises

  • ?Should suicide prevention efforts focus on depression treatment rather than substance-specific interventions?
  • ?Are non-cannabis illicit drugs more relevant to suicidality risk in women?
  • ?How do cultural factors affect the substance-suicidality relationship?

Trust & Context

Key Stat:
Depression (OR ~8) was the strongest suicide risk factor; cannabis was not independently significant
Evidence Grade:
Large population-based survey with comprehensive adjustment for confounders. Cross-sectional design limits causal inference.
Study Age:
Published in 2010. Subsequent research has continued to support the finding that confounding, particularly depression, explains much of the cannabis-suicidality association.
Original Title:
Suicidal ideation among young French adults: association with occupation, family, sexual activity, personal background and drug use.
Published In:
Journal of affective disorders, 123(1-3), 108-15 (2010)
Database ID:
RTHC-00426

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does cannabis increase suicide risk?

In this study, cannabis was not an independent predictor of suicidal ideation after accounting for depression and other factors. This is consistent with other large studies finding that the cannabis-suicide association is explained by underlying vulnerabilities rather than cannabis itself.

Why were other illicit drugs significant for women but not men?

The study found that non-cannabis illicit drug use was a significant predictor of suicidal ideation in women (OR 4.01) but not men. This may reflect gender-specific pathways between drug use and suicidality, possibly related to the different contexts in which men and women initiate illicit drug use.

Read More on RethinkTHC

Cite This Study

RTHC-00426·https://rethinkthc.com/research/RTHC-00426

APA

Legleye, S; Beck, F; Peretti-Watel, P; Chau, N; Firdion, J M. (2010). Suicidal ideation among young French adults: association with occupation, family, sexual activity, personal background and drug use.. Journal of affective disorders, 123(1-3), 108-15. https://doi.org/10.1016/j.jad.2009.10.016

MLA

Legleye, S, et al. "Suicidal ideation among young French adults: association with occupation, family, sexual activity, personal background and drug use.." Journal of affective disorders, 2010. https://doi.org/10.1016/j.jad.2009.10.016

RethinkTHC

RethinkTHC Research Database. "Suicidal ideation among young French adults: association wit..." RTHC-00426. Retrieved from https://rethinkthc.com/research/legleye-2010-suicidal-ideation-among-young

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.