Young adults, men, and sexual minorities had highest risk of co-occurring suicidality and cannabis use disorder

A nationally representative study identified men, emerging adults, Black/African American, Native, and sexual minority groups as having the highest risk of co-occurring suicidal ideation and cannabis use disorder.

Kelly, Lourah M et al.·Addictive behaviors·2021·Strong EvidenceCross-Sectional
RTHC-03237Cross SectionalStrong Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Strong Evidence
Sample
Not reported

What This Study Found

Men had twice the odds of co-occurring suicidal ideation and CUD (AOR=2.06). All older age groups had far lower odds than emerging adults (AORs 0.06-0.39). Black/African American adults had 4 times higher odds of co-occurring CUD and suicide attempts (AOR=4.05). Bisexual adults had over 3 times higher odds of co-occurring ideation and CUD (AOR=3.16). Native adults had over twice the odds (AOR=2.16).

Key Numbers

Men: AOR=2.06 for co-occurring ideation/CUD. Black/African American: AOR=4.05 for co-occurring attempts/CUD. Native: AOR=2.16 for ideation/CUD. Bisexual: AOR=3.16 for ideation/CUD. Gay/lesbian: AOR=2.04. Hispanic/Latinx: AOR=2.49 for attempts/CUD. Older groups: AOR=0.06-0.39 vs. emerging adults.

How They Did This

Combined five years (2015-2019) of NSDUH data. Multinomial logistic regressions tested demographic differences in odds of suicidality only, CUD only, and co-occurring CUD and suicidality. Controlled for survey year, major depressive episode, and other substance use disorders.

Why This Research Matters

Knowing which demographic groups carry the highest risk of co-occurring CUD and suicidality allows for targeted screening and prevention. The intersection of substance use and suicide risk is particularly dangerous, and certain groups are bearing a disproportionate burden.

The Bigger Picture

The racial and sexual orientation disparities identified here likely reflect structural factors including discrimination, reduced access to mental healthcare, and minority stress. Addressing co-occurring CUD and suicidality requires culturally responsive approaches that account for these intersecting vulnerabilities.

What This Study Doesn't Tell Us

Cross-sectional design. Self-reported CUD screening, not clinical diagnosis. Cannot determine temporal ordering. Some subgroup analyses may be underpowered. NSDUH excludes institutionalized and homeless populations.

Questions This Raises

  • ?What drives the especially high risk among Black/African American adults for co-occurring CUD and suicide attempts?
  • ?Would culturally tailored CUD treatment reduce suicidality in high-risk groups?
  • ?Are these disparities widening or narrowing over time?

Trust & Context

Key Stat:
Black/African American adults: 4x odds of co-occurring CUD and suicide attempts
Evidence Grade:
Five years of nationally representative data with appropriate covariate adjustment. Strong for identifying demographic risk patterns.
Study Age:
2021 study analyzing 2015-2019 NSDUH data.
Original Title:
Demographic risk factors for co-occurring suicidality and cannabis use disorders: Findings from a nationally representative United States sample.
Published In:
Addictive behaviors, 122, 107047 (2021)
Database ID:
RTHC-03237

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Which age group had the highest risk?

Emerging adults (ages 18-25) had by far the highest risk. All older age groups had 61-94% lower odds of co-occurring CUD and suicidality.

Were the racial disparities about cannabis use or suicidality specifically?

The study specifically examined co-occurrence. Black/African American adults had 4 times higher odds of having both CUD and suicide attempts simultaneously, not just one or the other, suggesting compounded vulnerability.

Read More on RethinkTHC

Cite This Study

RTHC-03237·https://rethinkthc.com/research/RTHC-03237

APA

Kelly, Lourah M; Drazdowski, Tess K; Livingston, Nicholas R; Zajac, Kristyn. (2021). Demographic risk factors for co-occurring suicidality and cannabis use disorders: Findings from a nationally representative United States sample.. Addictive behaviors, 122, 107047. https://doi.org/10.1016/j.addbeh.2021.107047

MLA

Kelly, Lourah M, et al. "Demographic risk factors for co-occurring suicidality and cannabis use disorders: Findings from a nationally representative United States sample.." Addictive behaviors, 2021. https://doi.org/10.1016/j.addbeh.2021.107047

RethinkTHC

RethinkTHC Research Database. "Demographic risk factors for co-occurring suicidality and ca..." RTHC-03237. Retrieved from https://rethinkthc.com/research/kelly-2021-demographic-risk-factors-for

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.