Cannabis Use Disorder Nearly Quadrupled Suicidal Ideation Risk in Women Veterans

Among women veterans, past-year cannabis use disorder was associated with nearly 4 times higher odds of suicidal ideation, and lifetime cannabis use doubled the odds of suicide plans.

Kameg, Brayden·Journal of the American Psychiatric Nurses Association·2025·Moderate Evidencecross-sectional survey
RTHC-06785Cross Sectional surveyModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
cross-sectional survey
Evidence
Moderate Evidence
Sample
N=131,344

What This Study Found

Women veterans had increased odds of suicidality compared to peers. Past-year cannabis use disorder increased odds of suicidal ideation nearly fourfold in women veterans (aOR=3.93, 95% CI: 1.21-13.81). Lifetime cannabis use doubled odds of suicide plans (aOR=2.02, 95% CI: 1.03-3.96). Cocaine and stimulant use also increased suicide plan odds.

Key Numbers

N=131,344. Cannabis use disorder and suicidal ideation in women vets: aOR=3.93 (95% CI: 1.21-13.81, p=.033). Lifetime cannabis use and suicide plans: aOR=2.02 (95% CI: 1.03-3.96, p=.040). Lifetime cocaine and plans: aOR=2.24 (95% CI: 1.20-4.05, p=.011).

How They Did This

Analysis of 2015-2019 NSDUH data (n=131,344). Binary logistic regression examining substance use and suicidality, adjusted for demographics, stratified by sex and veteran status.

Why This Research Matters

Women veterans face disproportionately high suicide rates. Identifying cannabis use disorder as a particularly strong risk factor provides a modifiable target for suicide prevention in this vulnerable population.

The Bigger Picture

The specificity of CUD (not combined drug use disorders) predicting suicidal ideation in women veterans suggests cannabis may play a unique role in suicidality for this population, potentially through its effects on mood regulation or social isolation.

What This Study Doesn't Tell Us

Cross-sectional NSDUH data cannot establish temporal or causal relationships. Small number of women veterans with CUD limits statistical power (wide confidence intervals). Self-reported substance use and suicidality may be underreported. Cannot distinguish between cannabis causing suicidality and suicidal individuals self-medicating with cannabis.

Questions This Raises

  • ?Does treating CUD in women veterans reduce suicidal ideation?
  • ?Why is CUD specifically (not combined drug use) associated with suicidality in women veterans?

Trust & Context

Key Stat:
Cannabis use disorder was associated with 3.93x higher odds of suicidal ideation in women veterans
Evidence Grade:
Large nationally representative sample with appropriate stratification, but cross-sectional design, wide confidence intervals, and self-report limit strength.
Study Age:
2025 publication with 2015-2019 NSDUH data.
Original Title:
The Association Between Substance Use and Suicidality Among Women Veterans, 2015 to 2019: A Secondary Analysis of the National Survey on Drug Use and Health.
Published In:
Journal of the American Psychiatric Nurses Association, 10783903251398530 (2025)
Database ID:
RTHC-06785

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Read More on RethinkTHC

Cite This Study

RTHC-06785·https://rethinkthc.com/research/RTHC-06785

APA

Kameg, Brayden. (2025). The Association Between Substance Use and Suicidality Among Women Veterans, 2015 to 2019: A Secondary Analysis of the National Survey on Drug Use and Health.. Journal of the American Psychiatric Nurses Association, 10783903251398530. https://doi.org/10.1177/10783903251398530

MLA

Kameg, Brayden. "The Association Between Substance Use and Suicidality Among Women Veterans, 2015 to 2019: A Secondary Analysis of the National Survey on Drug Use and Health.." Journal of the American Psychiatric Nurses Association, 2025. https://doi.org/10.1177/10783903251398530

RethinkTHC

RethinkTHC Research Database. "The Association Between Substance Use and Suicidality Among ..." RTHC-06785. Retrieved from https://rethinkthc.com/research/kameg-2025-the-association-between-substance

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.