How Racial Trauma Affects Substance Use Differently in Multi-Ethnic vs. Mono-Ethnic Young Adults

Racial trauma undermined the protective effects of psychological well-being on mental health and substance use, with distinct patterns for multi-ethnic versus mono-ethnic minority young adults.

Huh, Jimi et al.·Substance use & misuse·2025·Moderate Evidencecross-sectional survey
RTHC-06691Cross Sectional surveyModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
cross-sectional survey
Evidence
Moderate Evidence
Sample
N=59,529

What This Study Found

Among 59,529 racial/ethnic minority young adults, psychological well-being (PWB) was associated with fewer anxiety and depressive symptoms and lower substance use counts. However, racial trauma dampened these protective effects. For multi-ethnic young adults (25.3% of sample), depressive symptoms mediated the path from racial trauma to substance use differently than for mono-ethnic peers.

Key Numbers

N=59,529 racial/ethnic minority young adults. 25.3% identified as multi-racial/ethnic. PWB was associated with lower anxiety and depressive symptoms and fewer substances used across groups. Racial trauma significantly dampened the protective effects of PWB on mental health.

How They Did This

Combined three waves of the Healthy Minds Study (2021-2023) for self-identified racial/ethnic minority young adults. Moderated mediation path analyses stratified by mono- vs. multi-ethnicity, with multiple group analysis testing non-invariance.

Why This Research Matters

Americans identifying as two or more races are one of the fastest-growing demographic groups. Understanding how racial trauma uniquely affects substance use in this population can inform culturally tailored prevention.

The Bigger Picture

The finding that racial trauma undermines otherwise protective psychological resources has implications beyond substance use. It suggests that mental health interventions for minority young adults need to address racial trauma directly rather than relying solely on building general resilience.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish causation. Self-reported racial trauma and substance use may be subject to bias. The Healthy Minds Study samples college students, limiting generalizability to non-college populations.

Questions This Raises

  • ?What specific aspects of multi-ethnic identity create different vulnerability pathways?
  • ?Would interventions targeting depressive symptoms reduce substance use risk specifically in multi-ethnic young adults?

Trust & Context

Key Stat:
Racial trauma dampened the protective effects of psychological well-being on mental health across 59,529 minority young adults
Evidence Grade:
Large nationally representative sample with validated measures, but cross-sectional design limits causal conclusions.
Study Age:
2025 publication using 2021-2023 Healthy Minds Study data.
Original Title:
Racial Trauma among Multi-Ethnic Minority Young Adults Affects Nicotine, Alcohol, and Cannabis Use Differently than among Mono-Ethnic Minority Young Adults.
Published In:
Substance use & misuse, 60(14), 2154-2162 (2025)
Database ID:
RTHC-06691

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Read More on RethinkTHC

Cite This Study

RTHC-06691·https://rethinkthc.com/research/RTHC-06691

APA

Huh, Jimi; Lee, Ryan; Pickering, Trevor A; Oh, Hans; Arpawong, Thalida Em. (2025). Racial Trauma among Multi-Ethnic Minority Young Adults Affects Nicotine, Alcohol, and Cannabis Use Differently than among Mono-Ethnic Minority Young Adults.. Substance use & misuse, 60(14), 2154-2162. https://doi.org/10.1080/10826084.2025.2537101

MLA

Huh, Jimi, et al. "Racial Trauma among Multi-Ethnic Minority Young Adults Affects Nicotine, Alcohol, and Cannabis Use Differently than among Mono-Ethnic Minority Young Adults.." Substance use & misuse, 2025. https://doi.org/10.1080/10826084.2025.2537101

RethinkTHC

RethinkTHC Research Database. "Racial Trauma among Multi-Ethnic Minority Young Adults Affec..." RTHC-06691. Retrieved from https://rethinkthc.com/research/huh-2025-racial-trauma-among-multiethnic

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.