A cannabis user with severe vomiting also needed jaw surgery, highlighting CHS complications

A woman with chronic vomiting from cannabinoid hyperemesis syndrome developed dangerously low potassium levels that had to be corrected before she could undergo jaw fracture surgery.

RTHC-00915Case ReportPreliminary Evidence2015RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Case Report
Evidence
Preliminary Evidence
Sample
Not reported

What This Study Found

A 42-year-old woman was admitted to the hospital with a jaw fracture. Her lab work revealed dangerously low potassium and metabolic alkalosis caused by weeks of chronic vomiting, multiple times daily. The vomiting was attributed to cannabinoid hyperemesis syndrome (CHS).

The CHS had to be addressed before her jaw surgery could proceed. Treatment involved fluid resuscitation, antiemetic medications, and marijuana cessation. Once her electrolytes normalized and vomiting stopped, she was able to undergo surgical repair of her mandibular fracture.

The authors emphasized that the dental and surgical communities should be aware of CHS, especially as cannabis legalization expands. They noted the paradox that while cannabis is known for its antiemetic properties, it can produce the opposite effect in some chronic users.

Key Numbers

One patient, age 42. Severe hypokalemia and metabolic alkalosis from weeks of daily vomiting. Treatment required fluid resuscitation before surgical repair could proceed.

How They Did This

Single case report documenting CHS presentation in a surgical patient, with discussion of clinical implications for the dental community.

Why This Research Matters

CHS can create medical complications that interfere with other treatments. This case illustrates how chronic vomiting from CHS caused electrolyte imbalances severe enough to delay necessary surgery, highlighting the condition's broader medical impact.

The Bigger Picture

As cannabis legalization expands, medical and dental professionals are encountering CHS more frequently. Cases like this one demonstrate that CHS is not just a gastrointestinal issue but can affect surgical planning and overall patient safety.

What This Study Doesn't Tell Us

Single case report with no ability to generalize. The patient had comorbid conditions (hypertension, myasthenia gravis) that may have complicated the picture.

Questions This Raises

  • ?How often does CHS go unrecognized in surgical patients?
  • ?Should pre-surgical screening include questions about cannabis use patterns?
  • ?Could CHS-related electrolyte imbalances pose risks during anesthesia?

Trust & Context

Key Stat:
Severe hypokalemia from weeks of daily CHS vomiting
Evidence Grade:
Single case report documenting CHS complications in a surgical context.
Study Age:
Published in 2015 as CHS was gaining wider recognition.
Original Title:
Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review.
Published In:
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 73(10), 1907-10 (2015)
Database ID:
RTHC-00915

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal StudyOne case or non-human subjects
This study

Describes what happened to one person or a small group.

What do these levels mean? →

Frequently Asked Questions

Can CHS affect your ability to have surgery?

Yes. In this case, chronic vomiting from CHS caused severe electrolyte imbalances that needed to be corrected before the patient could safely undergo jaw surgery.

Is the dental community aware of CHS?

The authors of this case report argued that many dental professionals may not be, especially given the widespread understanding of cannabis as an antiemetic rather than a potential cause of vomiting.

Read More on RethinkTHC

Cite This Study

RTHC-00915·https://rethinkthc.com/research/RTHC-00915

APA

Beech, Robert A; Sterrett, David R; Babiuk, James; Fung, Henry. (2015). Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review.. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 73(10), 1907-10. https://doi.org/10.1016/j.joms.2015.03.059

MLA

Beech, Robert A, et al. "Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review.." Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2015. https://doi.org/10.1016/j.joms.2015.03.059

RethinkTHC

RethinkTHC Research Database. "Cannabinoid Hyperemesis Syndrome: A Case Report and Literatu..." RTHC-00915. Retrieved from https://rethinkthc.com/research/beech-2015-cannabinoid-hyperemesis-syndrome-a

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.