Mental Health App Reduced Anxiety, Depression, and Cannabis Use in University Students

A randomized trial of 1,489 university students found the Minder mental health app significantly reduced anxiety and depression symptoms, with provisional support for reducing cannabis use frequency over 30 days.

Vereschagin, Melissa et al.·Journal of medical Internet research·2024·Strong EvidenceRandomized Controlled Trial
RTHC-05782Randomized Controlled TrialStrong Evidence2024RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Randomized Controlled Trial
Evidence
Strong Evidence
Sample
N=743

What This Study Found

The Minder app produced significant reductions in anxiety (GAD-7: d=-0.17, p<0.001) and depression (PHQ-9: d=-0.11, p=0.007). Statistically significant reductions were also found for cannabis use frequency and typical alcohol consumption. 77.1% of intervention participants accessed at least one app component. Retention was high: 79% intervention and 83% control completed follow-up.

Key Numbers

1,489 students. Anxiety: d=-0.17, p<0.001. Depression: d=-0.11, p=0.007. Significant reductions in cannabis use frequency and typical drinks. 77.1% app engagement. 79% retention. Alcohol AUDIT-C reduction not significant (p=0.23).

How They Did This

Two-arm parallel-assignment single-blinded 30-day RCT. 1,489 university students randomized to Minder app (n=743) or waitlist control (n=746). App delivered evidence-based content via chatbot, connected users with services, and provided peer coaching. ITT analysis with generalized linear mixed-effects models.

Why This Research Matters

University students face high rates of mental health and substance use challenges but rarely seek formal treatment. A scalable digital intervention that addresses both simultaneously could be integrated into existing university systems to reach students who would not otherwise get help.

The Bigger Picture

Digital mental health interventions are particularly well-suited to university populations who are already digitally native. The finding that a single app can address both mental health symptoms and substance use simultaneously is more efficient than separate interventions.

What This Study Doesn't Tell Us

Small effect sizes (d=-0.11 to -0.17). Waitlist control does not control for attention/expectation effects. 30-day follow-up is short. Cannabis and alcohol use were secondary outcomes. Self-reported outcomes.

Questions This Raises

  • ?Would effects persist beyond 30 days?
  • ?Would a longer intervention produce larger effects?
  • ?Can Minder be effective without the peer coaching component?
  • ?How does it compare to in-person counseling?

Trust & Context

Key Stat:
Significant reductions in anxiety, depression, and cannabis use frequency
Evidence Grade:
Large well-powered RCT with good retention, though small effect sizes, short follow-up, and waitlist control design are limitations.
Study Age:
2024 study
Original Title:
Effectiveness of the Minder Mobile Mental Health and Substance Use Intervention for University Students: Randomized Controlled Trial.
Published In:
Journal of medical Internet research, 26, e54287 (2024)
Database ID:
RTHC-05782

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled TrialGold standard for testing treatments
This study
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal Study

Participants are randomly assigned to treatment or placebo groups to test cause and effect.

What do these levels mean? →

Frequently Asked Questions

Can a phone app help with mental health and cannabis use?

This trial of 1,489 university students found the Minder app significantly reduced anxiety and depression symptoms, with additional reductions in cannabis use frequency over 30 days.

How well did students engage with the mental health app?

77% of students in the intervention group used at least one app component, and 79% completed the follow-up assessment, suggesting good acceptability among university students.

Read More on RethinkTHC

Cite This Study

RTHC-05782·https://rethinkthc.com/research/RTHC-05782

APA

Vereschagin, Melissa; Wang, Angel Y; Richardson, Chris G; Xie, Hui; Munthali, Richard J; Hudec, Kristen L; Leung, Calista; Wojcik, Katharine D; Munro, Lonna; Halli, Priyanka; Kessler, Ronald C; Vigo, Daniel V. (2024). Effectiveness of the Minder Mobile Mental Health and Substance Use Intervention for University Students: Randomized Controlled Trial.. Journal of medical Internet research, 26, e54287. https://doi.org/10.2196/54287

MLA

Vereschagin, Melissa, et al. "Effectiveness of the Minder Mobile Mental Health and Substance Use Intervention for University Students: Randomized Controlled Trial.." Journal of medical Internet research, 2024. https://doi.org/10.2196/54287

RethinkTHC

RethinkTHC Research Database. "Effectiveness of the Minder Mobile Mental Health and Substan..." RTHC-05782. Retrieved from https://rethinkthc.com/research/vereschagin-2024-effectiveness-of-the-minder

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.