Most Synthetic Cannabinoid Users Aren't Trying to Avoid Drug Tests

Among 124 patients evaluated for new psychoactive substance use, 69% involved synthetic cannabinoids, and nearly half used them primarily to get high rather than to avoid drug screening.

Tebo, Collin et al.·Journal of psychoactive drugs·2021·Moderate EvidenceCross-Sectional
RTHC-03570Cross SectionalModerate Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=124

What This Study Found

Of 124 NPS cases, 86 (69%) involved SCRAs. Most patients (68.8%) had used SCRAs before, 47.7% found them very easy to obtain, and 48.8% used primarily to get high. Only 6.9% used SCRAs to avoid drug testing, and 4.6% as a marijuana alternative, suggesting an independent culture around SCRA use.

Key Numbers

124 NPS cases; 86 (69%) involved SCRAs; 68.8% had used before; 47.7% found very easy to obtain; 44.2% paid for substances, 32.6% got free; 48.8% used to get high; 6.9% to avoid drug testing; 4.6% as marijuana alternative.

How They Did This

Cross-sectional analysis of 124 patients with suspected new psychoactive substance exposure who received medical toxicology consultation, with qualitative interviews capturing knowledge, attitudes, beliefs, and practices.

Why This Research Matters

The finding that SCRA use has developed its own culture separate from marijuana substitution challenges the assumption that users primarily choose synthetics to avoid detection, and has implications for prevention messaging.

The Bigger Picture

If synthetic cannabinoid use is driven more by a desire for the specific high rather than as a marijuana substitute, harm-reduction efforts need to address the unique appeal of these substances rather than simply improving access to cannabis.

What This Study Doesn't Tell Us

Medical toxicology consultations represent severe cases, not typical users; convenience sample; self-reported motivations may not capture all reasons; limited to patients seeking medical care.

Questions This Raises

  • ?What characteristics of the SCRA high are appealing to users beyond marijuana effects?
  • ?Would cannabis legalization reduce SCRA use if most users aren't seeking a marijuana substitute?

Trust & Context

Key Stat:
Only 6.9% of synthetic cannabinoid users were trying to avoid drug testing
Evidence Grade:
Cross-sectional clinical sample with qualitative data, limited to patients receiving medical toxicology consultation.
Study Age:
Published in 2021.
Original Title:
Characterizing Trends in Synthetic Cannabinoid Receptor Agonist Use from Patient Clinical Evaluations during Medical Toxicology Consultation.
Published In:
Journal of psychoactive drugs, 53(3), 207-214 (2021)
Database ID:
RTHC-03570

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Why do people use synthetic cannabinoids?

Nearly half (48.8%) reported using primarily to get high, suggesting an independent appeal. Only 6.9% used to avoid drug testing and 4.6% as a marijuana alternative, challenging the common assumption about why people choose synthetics.

How accessible are synthetic cannabinoids?

Nearly half (47.7%) of users described them as very easy to obtain, and about a third (32.6%) acquired them for free, suggesting wide availability.

Read More on RethinkTHC

Cite This Study

RTHC-03570·https://rethinkthc.com/research/RTHC-03570

APA

Tebo, Collin; Mazer-Amirshahi, Maryann; Wax, Paul; Campleman, Sharan; Boyer, Edward; Brent, Jeffrey; Sheth, Amit; Daniuaityte, Raminta; Carlson, Robert. (2021). Characterizing Trends in Synthetic Cannabinoid Receptor Agonist Use from Patient Clinical Evaluations during Medical Toxicology Consultation.. Journal of psychoactive drugs, 53(3), 207-214. https://doi.org/10.1080/02791072.2020.1851826

MLA

Tebo, Collin, et al. "Characterizing Trends in Synthetic Cannabinoid Receptor Agonist Use from Patient Clinical Evaluations during Medical Toxicology Consultation.." Journal of psychoactive drugs, 2021. https://doi.org/10.1080/02791072.2020.1851826

RethinkTHC

RethinkTHC Research Database. "Characterizing Trends in Synthetic Cannabinoid Receptor Agon..." RTHC-03570. Retrieved from https://rethinkthc.com/research/tebo-2021-characterizing-trends-in-synthetic

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.