Nearly Half of Young Cannabis Users Also Use Delta-8 Products — With More Consequences

45.6% of young adult cannabis users also use derived products like delta-8 THC, driven by higher enhancement and coping motives, with co-use linked to more consequences.

LoParco, Cassidy R et al.·Substance use & addiction journal·2026·Moderate EvidenceCross-Sectional
RTHC-08444Cross SectionalModerate Evidence2026RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=4,031

What This Study Found

Among past-month cannabis users, 54.4% used cannabis only while 45.6% co-used cannabis and DICPs. Greater enhancement and coping motives predicted co-use. Cannabis-DICP co-use was associated with greater psychophysiological and sociobehavioral consequences. Consequences were bidirectionally associated with motives — higher consequences predicted stronger motives, which predicted more co-use.

Key Numbers

1,968 past-month cannabis users analyzed. 54.4% cannabis-only, 45.6% cannabis+DICP co-use. Enhancement and coping motives predicted co-use. Co-use associated with greater psychophysiological and sociobehavioral consequences. Bidirectional mediation confirmed.

How They Did This

Cross-sectional mediation analysis of 1,968 past-month cannabis users (from 4,031 surveyed US young adults aged 18-34). Two mediation models examined: motives → use category → consequences, and consequences → motives → use category.

Why This Research Matters

Delta-8 and other derived products have exploded in popularity but are essentially unregulated. Nearly half of cannabis users adding these products — with more consequences — represents a rapidly growing public health concern.

The Bigger Picture

The finding that consequences drive stronger motives which drive more co-use suggests a vicious cycle: people experiencing problems from cannabis use may escalate to include DICPs, creating more problems, stronger motives, and deeper engagement.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish temporal ordering despite mediation models. Self-reported use and consequences. ~50% cannabis user design may limit generalizability. DICP category is broad (delta-8, delta-10, etc.).

Questions This Raises

  • ?Do DICP users recognize they're using potentially riskier products?
  • ?Would DICP regulation reduce co-use consequences?
  • ?Are coping-motivated users at particular risk of escalation?

Trust & Context

Key Stat:
Evidence Grade:
Large sample with sophisticated mediation analysis, limited by cross-sectional design and self-reported data.
Study Age:
Published 2026 with 2023 survey data, capturing the peak of the DICP market.
Original Title:
Cannabis and Derived Cannabis Use, Motives, and Consequences Among US Young Adults: Findings From a Cross-Sectional Mediation Study.
Published In:
Substance use & addiction journal, 47(1), 57-67 (2026)
Database ID:
RTHC-08444

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Are young people combining regular cannabis with delta-8 products?

Yes — nearly half (45.6%) of young adult cannabis users also use derived products like delta-8 THC, driven by desires for enhanced effects and emotional coping.

Is co-using cannabis and delta-8 products riskier?

The study found co-users experienced more negative consequences — both physical/psychological and social/behavioral — compared to cannabis-only users, and these consequences fed back into stronger motives for continued co-use.

Read More on RethinkTHC

Cite This Study

RTHC-08444·https://rethinkthc.com/research/RTHC-08444

APA

LoParco, Cassidy R; Cui, Yuxian; Rossheim, Matthew E; Chakraborty, Rishika; Speer, Morgan; Chen-Sankey, Julia; Cavazos-Rehg, Patricia A; Berg, Carla J. (2026). Cannabis and Derived Cannabis Use, Motives, and Consequences Among US Young Adults: Findings From a Cross-Sectional Mediation Study.. Substance use & addiction journal, 47(1), 57-67. https://doi.org/10.1177/29767342251355094

MLA

LoParco, Cassidy R, et al. "Cannabis and Derived Cannabis Use, Motives, and Consequences Among US Young Adults: Findings From a Cross-Sectional Mediation Study.." Substance use & addiction journal, 2026. https://doi.org/10.1177/29767342251355094

RethinkTHC

RethinkTHC Research Database. "Cannabis and Derived Cannabis Use, Motives, and Consequences..." RTHC-08444. Retrieved from https://rethinkthc.com/research/loparco-2026-cannabis-and-derived-cannabis

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.