Cannabis Alone Did Not Raise Suicide Risk in Veterans, but Combined with Heavy Drinking It Did

Among 1,098 US veterans, cannabis use alone was not linked to higher suicidal ideation, but combining cannabis with hazardous drinking was associated with the greatest risk for suicidal behavior.

Grove, Jeremy L et al.·International journal of mental health and addiction·2025·Moderate EvidenceCross-Sectional
RTHC-06592Cross SectionalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=1,098

What This Study Found

Veterans who used both cannabis and alcohol hazardously had greater odds of suicidal ideation and elevated suicide risk than any other group, including those who used either substance alone. Notably, cannabis use alone was not associated with greater odds of suicidal ideation or elevated suicide risk compared to the non-using group. However, cannabis use (alone or with alcohol) was associated with higher rates of non-suicidal self-injury (NSSI).

Key Numbers

1,098 veterans; 78% male; concurrent use (HD+CU) had greatest odds of suicidal ideation and elevated suicide risk; CU alone: no elevated suicide risk; both CU only and HD+CU associated with higher NSSI rates

How They Did This

Cross-sectional survey of 1,098 US veterans (78% male, 67% White). Compared four groups: hazardous drinking only, cannabis use only, concurrent use, and neither. Assessed past-year suicidal ideation, elevated risk for suicidal behavior, and past-year NSSI via validated questionnaires, controlling for covariates.

Why This Research Matters

The nuanced finding that cannabis alone did not increase suicide risk while combined use did suggests that polysubstance use patterns, not individual substances in isolation, may drive the most concerning outcomes in veteran populations.

The Bigger Picture

Veteran suicide prevention efforts typically focus on alcohol and mental health treatment. This data suggests concurrent cannabis and alcohol use deserves specific clinical attention as a risk marker, while cannabis alone may carry different risk profiles for different types of self-harm.

What This Study Doesn't Tell Us

Cross-sectional design cannot establish causation. Self-report survey may undercount sensitive behaviors. Predominantly male, White sample may not generalize to all veterans. Could not assess cannabis use frequency, quantity, or type.

Questions This Raises

  • ?What mechanisms make concurrent cannabis and alcohol use particularly risky for suicidal behavior?
  • ?Why is cannabis use associated with NSSI but not suicidal ideation when used alone?

Trust & Context

Key Stat:
Evidence Grade:
Moderate: adequate sample size with multivariate adjustment, but cross-sectional design and self-report limitations.
Study Age:
2025 publication
Original Title:
Hazardous Drinking and Cannabis Use in Military Veterans: Comparative Associations with Risk for Suicidal and Non-Suicidal Self-Injury.
Published In:
International journal of mental health and addiction (2025)
Database ID:
RTHC-06592

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

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Cite This Study

RTHC-06592·https://rethinkthc.com/research/RTHC-06592

APA

Grove, Jeremy L; Beckham, Jean C; Calhoun, Patrick S; Dedert, Eric A; Pugh, Mary J; Kimbrel, Nathan A. (2025). Hazardous Drinking and Cannabis Use in Military Veterans: Comparative Associations with Risk for Suicidal and Non-Suicidal Self-Injury.. International journal of mental health and addiction. https://doi.org/10.1007/s11469-025-01453-x

MLA

Grove, Jeremy L, et al. "Hazardous Drinking and Cannabis Use in Military Veterans: Comparative Associations with Risk for Suicidal and Non-Suicidal Self-Injury.." International journal of mental health and addiction, 2025. https://doi.org/10.1007/s11469-025-01453-x

RethinkTHC

RethinkTHC Research Database. "Hazardous Drinking and Cannabis Use in Military Veterans: Co..." RTHC-06592. Retrieved from https://rethinkthc.com/research/grove-2025-hazardous-drinking-and-cannabis

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.