Frequent cannabis use predicted worse depression and delinquency in young women of color over one year

Using cannabis 20+ times monthly was associated with 2.71 times higher odds of school suspension, increased depressive symptoms, and increased delinquent behaviors. Cross-lagged models showed frequent cannabis use predicted depressive symptoms 6 months later and higher delinquency at both 6 and 12 months, suggesting cannabis preceded the negative outcomes rather than the reverse.

Prospective cohort of 545 sexually active female adolescents and young adults in an inner-city setting. 94% identified as people of color. Questionnaires at three visits over one year. Multivariable regression and cross-lagged panel models.

Young women of color are underrepresented in cannabis research despite potentially facing compounded risks from substance use and structural inequities. The prospective design strengthens the case that frequent cannabis use contributes to these negative outcomes rather than simply co-occurring.

The finding that frequent cannabis use predicts future depression and delinquency in this population suggests a window for intervention before consequences accumulate, particularly in communities where both cannabis access and structural disadvantages converge.

Self-reported cannabis use and outcomes. Specific population (sexually active, inner-city, predominantly women of color) limits generalizability. Threshold of 20+ times monthly represents heavy use; lighter use patterns were not examined separately. Potential unmeasured confounders.